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Bougainvillea
Bougainvillea is one of the most important and popular perennial ornamental crops in floriculture for multipurpose use and a very suitable plant for...
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Population stability and asymmetric migration of caddisfly populations, Stenopsyche marmorata (Stenopsychidae), in a forest–agriculture landscape
In river systems, frequent floods generally decrease the abundance of riverine species, and recent studies have reported that the degree of flood...
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Tuberose
Tuberose (Polianthes tuberosa Linn.) is a monotypic monocot genus, perennial, bulbous plant belonging to the family Amaryllidaceae comprising about a...
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Chrysanthemum
Chrysanthemum with its large number of cultivars in respect of growth habit, size, color, and shape of bloom has attracted its admirers and...
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Non-Mendelian Genetics: Finding of Transposable Elements in Corns and Flies
The essence of Mendelian genetics is the rule of chromosome segregation and the independent assortment of different chromosomes. However, genes on...
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Induced Mutagenesis for Crop Improvement
Induced mutagenesis is one of the most powerful strategies for creating genetic diversity and identifying critical regulatory genes for economically...
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A general mathematical model for coevolutionary dynamics of mutualisms with partner discrimination
Mutualisms (reciprocally beneficial heterospecific interactions) are thought as susceptible to exploitation by “cheaters” receiving benefits from...
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Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene
The Nakano cataract mouse (NCT) manifests a wavy coat for their first hair as a genetic trait. In this study, we explored the molecular genetic basis...
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Identification and structural characterization of a pathogenic ARSA missense variant in two consanguineous families from Jammu and Kashmir (India) with late infantile metachromatic leukodystrophy
BackgroundMetachromatic leukodystrophy (MLD) is a rare lysosomal storage disorder caused by a deficiency of Arylsulfatase A (ARSA) enzyme activity....
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Altered conformational dynamics contribute to species-specific effects of cytochrome c mutations on caspase activation
Variants in the gene encoding human cytochrome c ( CYCS ) cause mild autosomal dominant thrombocytopenia. Despite high sequence conservation between...
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Molecular genetics, neuroimaging outcomes, and structural analyses of novel and recurrent variants of WDR62 gene in two consanguineous Pakistani families with autosomal recessive primary microcephaly
BackgroundAutosomal recessive primary microcephaly (MCPH) is a rare neurodevelopmental and genetically heterogeneous disorder, characterized by small...
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Mutagenesis and TILLING in the Era of Precise Genome Editing
The human population is burgeoning and land resource to grow crops is decreasing day by day impacted by climate change. Feeding mankind remains a...
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Fungicide sensitivity of isolates of Sclerotinia sclerotiorum from different hosts and regions in Brazil and phenotypic instability of thiophanate-methyl resistant isolates
Fungicide application is the most widely adopted method to control white mold epidemics in several crops. The objectives of this study were to assess...
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Tn5 Transposon-based Mutagenesis for Engineering Phage-resistant Strains of Escherichia coli BL21 (DE3)
Escherichia coli is a preferred strain for recombinant protein production, however, it is often plagued by phage infection during experimental...
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Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators
The cavity-creating p53 cancer mutation Y220C is an ideal paradigm for develo** small-molecule drugs based on protein stabilization. Here, we have...
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Compound heterozygous mutations in a mouse model of Leber congenital amaurosis reveal the role of CCT2 in photoreceptor maintenance
TRiC/CCT is a chaperonin complex required for the folding of cytoplasmic proteins. Although mutations in each subunit of TRiC/CCT are associated with...
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The near-isogenic line containing the Sletr1-2 locus exhibited longer postharvest fruit shelf-life under the genetic background of commercial tomato
Tomato with prolonged fruit shelf life and improved postharvest quality would be an interesting commodity for breeders and consumers. A weak ethylene...
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Chloroplast genome characteristics and phylogeny of the sinodielsia clade (apiaceae: apioideae)
BackgroundThe Sinodielsia clade of the subfamily Apioideae (Apiacieae) was established in 2008, and it is composed of 37 species from 17 genera. Its...
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Preliminary comparative analysis of the genomes of selected field reisolates of the Mycoplasma synoviae vaccine strain MS-H reveals both stable and unstable mutations after passage in vivo
BackgroundGenomic comparison of Mycoplasma synoviae vaccine strain MS-H and the MS-H parental strain 86,079/7NS established a preliminary profile of...
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Identifying Lymph Node Metastasis-Related Factors in Breast Cancer Using Differential Modular and Mutational Structural Analysis
Complex diseases are generally caused by disorders of biological networks and/or mutations in multiple genes. Comparisons of network topologies...
