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Chromosomal gene of hybrid multisensor histidine kinase is involved in motility regulation in the rhizobacterium Azospirillum baldaniorum Sp245 under mechanical and water stress
Azospirillum alphaproteobacteria, which live in the rhizosphere of many crops, are used widely as biofertilizers. Two-component signal transduction...
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The two-component system CepRS regulates the cephamycin C biosynthesis in Streptomyces clavuligerus F613-1
During industrial fermentation, Streptomyces clavuligerus F613-1 simultaneously produces primary product clavulanic acid (CA) and cephamycin C. The...
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In vitro oogenesis from murine premeiotic germ cells using a new three-dimensional culture system
A faithful reconstitution of the complete process of oogenesis in vitro is helpful for understanding the molecular mechanisms, genetics, and...
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FGF12 is a novel component of the nucleolar NOLC1/TCOF1 ribosome biogenesis complex
Among the FGF proteins, the least characterized superfamily is the group of fibroblast growth factor homologous factors (FHFs). To date, the main...
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Engineering Whole-Cell Biosensors for Enhanced Detection of Environmental Antibiotics Using a Synthetic Biology Approach
Bacterial Two component systems have evolved with many intricate sensory apparatuses for external stimuli like light, temperature, oxygen, pH and...
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Combining silvopastoral systems with forest conservation: The caíva system in the Araucaria Forest, Southern Brazil
In Southern Brazil, caívas , agroforestry systems within patches of Araucaria Forest that include cattle production, have been used historically...
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Multifaceted regulation of siderophore synthesis by multiple regulatory systems in Shewanella oneidensis
Siderophore-dependent iron uptake is a mechanism by which microorganisms scavenge and utilize iron for their survival, growth, and many specialized...
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Global transcriptome analyses and regulatory mechanisms in Halothece sp. PCC 7418 exposed to abiotic stresses
Halotolerant species are of interest since they occur naturally in environments with excess toxic ions. The cyanobacterium Halothece sp. PCC 7418...
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The Wsp chemosensory system modulates c-di-GMP-dependent biofilm formation by integrating DSF quorum sensing through the WspR-RpfG complex in Lysobacter
The ubiquitous Wsp (wrinkly spreader phenotype) chemosensory system and DSF (diffusible signal factor) quorum sensing are two important chemically...
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Role of T cells in liver metastasis
The liver is a major metastatic site (organ) for gastrointestinal cancers (such as colorectal, gastric, and pancreatic cancers) as well as...
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Structural Characteristics of the Thalamocortical System and α-Rhythm in Mentally Healthy Subjects and Schizophrenic Patients
AbstractCurrent knowledge on morphological and functional abnormalities of the thalamocortical system (TCS) in schizophrenia is incomplete and...
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Sensor system for analysis of biofilm sensitivity to ampicillin
AbstractThe resistance of biofilms to antibiotics is a key factor that makes bacterial infections unsusceptible to antimicrobial therapy. The results...
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Inhibition of S6K lowers age-related inflammation and increases lifespan through the endolysosomal system
Suppression of target of rapamycin complex 1 (TORC1) by rapamycin ameliorates aging in diverse species. S6 kinase (S6K) is an essential mediator, but...
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Combined transcriptomic and metabolomic analysis of Salmonella in the presence or absence of PhoP–PhoQ system under low Mg2+ conditions
IntroductionPrevious reports revealed the role played by Salmonella PhoP–PhoQ system in virulence activation, antimicrobial tolerance and...
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Ectopic expression of GmHP08 enhances resistance of transgenic Arabidopsis toward drought stress
Key messageEctopic expression of
Glycine max two-component system memberGmHP08 inArabidopsis enhanced drought tolerance of transgenic plants,... -
Hik28-dependent and Hik28-independent ABC transporters were revealed by proteome-wide analysis of ΔHik28 under combined stress
Synechocystis histidine kinase, Sll0474: Hik28, a signal protein in a two-component signal transduction system, plays a critical role in responding...
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Development of an efficient ClosTron system for gene disruption in Ruminiclostridium papyrosolvens
AbstractRuminiclostridium papyrosolvens is an anaerobic, mesophilic, and cellulolytic clostridia, promising consolidated bioprocessing (CBP)...
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The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner
Soil bacteria often harbour various toxins to against eukaryotic or prokaryotic. Diffusible signal factors (DSFs) represent a unique group of quorum...
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Protein Dynamics in Phosphoryl-Transfer Signaling Mediated by Two-Component Systems
The ability to perceive the environment, an essential attribute in living organisms, is linked to the evolution of signaling proteins that recognize... -
A Zur-mediated transcriptional regulation of the zinc export system in Pseudomonas aeruginosa
The control of cellular zinc (Zn) concentrations by dedicated import and export systems is essential for the survival and virulence of Pseudomonas...