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Cardiovascular Imaging Databases: Building Machine Learning Algorithms for Regenerative Medicine
Purpose of ReviewMyocardial regeneration is a promising alternative to heart transplantation, but the ideal stem cell type remains unknown due to...
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Regenerative Approaches in the Nervous System
The nervous system is the most unique system of the human body in more than one way. The excitable tissue that forms the nervous system generates and...
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The Effects of Different Regenerative Treatments after Tooth Avulsion
Purpose of ReviewTraumatic injury to the teeth can cause dental avulsion. There is little time to return the tooth to its socket. Also, after tooth...
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Stem Cell Therapy After Neurological Injuries
Axonal degeneration, inflammation, neuronal death, and cytoarchitectural distortion can result from neurological injuries in both the central and...
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Development of Matrix Metalloproteinases-Mediated Extracellular Matrix Remodeling in Regenerative Medicine: A Mini Review
Extracellular matrix (ECM) components confer biomechanical properties, maintain cell phenotype and mediate tissue homeostasis. ECM remodeling is...
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The Potential of miR-21 in Stem Cell Differentiation and its Application in Tissue Engineering and Regenerative Medicine
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are two important types of non-coding RNAs that are not translated into protein. These...
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Landscape for Regenerative Medicine Manufacturing in Japan
In Japan, 6 years have passed since two important regenerative medicine laws came into force in November 2014 — the Act on the Safety of Regenerative...
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Recent Advances in Regenerative Medicine of the Liver and Bile Duct System by Chemically Induced Liver Progenitor Cells (CLiPs) in Nagasaki Experience
Liver transplantation is the only treatment for end-stage liver failure. Although the development of hepatocyte therapy is expected, hepatocyte...
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Stem Cell Therapy: Significance and Applications of Stem Cell Products in Tissue Engineering and Regenerative Medicine
This chapter concentrated mainly on the use of stem cells and their products in tissue engineering and regenerative medicine. It showed the promising...
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Regulatory Aspects of Cell and Gene Therapy Products: The Japanese Perspective
Regulations for regenerative medicine for human use, such as cell and gene therapy (CGT), have evolved in accordance with advancements in clinical...
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Improving Autologous Fat Grafting in Regenerative Surgery through Stem Cell-Assisted Lipotransfer
Autologous fat transplantation -i.e., lipofilling- has become a promising and popular technique in aesthetic and reconstructive surgery with several...
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A Systematic Review of Stem Cell Differentiation into Keratinocytes for Regenerative Applications
To improve wound healing or treatment of other skin diseases, and provide model cells for skin biology studies, in vitro differentiation of stem...
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Advances in combined application of dental stem cells and small-molecule drugs in regenerative medicine
Teeth are a kind of masticatory organs of special histological origin, unique to vertebrates, playing an important role in chewing, esthetics, and...
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How to establish infrastructures to achieve more efficient regenerative medicine?
The field of regenerative medicine (RM) as an innovative technology has the ability to affect the healthcare system. It develops a variety of...
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Evolution of Stem Cells in Cardio-Regenerative Therapy
Cardiovascular disease (CVD) remains an increasing global threat. It is one of the major causes for morbidity and mortality. Despite the current...
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Mesenchymal Stem Cell-Derived Extracellular Vesicles: The Novel Therapeutic Option for Regenerative Dentistry
Dental mesenchymal stem cells (MSCs) are characterized by unlimited self-renewal ability and high multidirectional differentiation potential. Since...
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Dental-derived mesenchymal stem cell sheets: a prospective tissue engineering for regenerative medicine
Stem cells transplantation is the main method of tissue engineering regeneration treatment, the viability and therapeutic efficiency are limited....
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Prospects of Mesenchymal Stem Cell Secretome in Veterinary Regenerative Therapy
Regenerative medicine, a branch of translational research, comprises the generation and use of therapeutic stem cells. The mesenchymal stem cells...
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Stem Cell Therapy After Neurological Injuries
Axonal degeneration, inflammation, neuronal death, and cytoarchitectural distortion can result from neurological injuries in both the central and...
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Regenerative Medicine Application of Mesenchymal Stem Cells
Mesenchymal stem cell (MSC) has recently generated interest in regenerative medicine. For the definition of MSC, three criteria have been proposed –...