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In vivo simultaneous nonlinear absorption Raman and fluorescence (SNARF) imaging of mouse brain cortical structures
Label-free multiphoton microscopy is a powerful platform for biomedical imaging. Recent advancements have demonstrated the capabilities of transient...
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What is the ability of inflamed endothelium to uptake exogenous saturated fatty acids? A proof-of-concept study using spontaneous Raman, SRS and CARS microscopy
Endothelial cells (EC) in vivo buffer and regulate the transfer of plasma fatty acid (FA) to the underlying tissues. We hypothesize that inflammation...
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Raman microscopy-based quantification of the physical properties of intracellular lipids
The physical properties of lipids, such as viscosity, are homeostatically maintained in cells and are intimately involved in physiological roles....
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Raman spectral cytopathology for cancer diagnostic applications
Raman spectroscopy can provide a rapid, label-free, nondestructive measurement of the chemical fingerprint of a sample and has shown potential for...
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Raman spectroscopy biochemical characterisation of bladder cancer cisplatin resistance regulated by FDFT1: a review
Bladder cancer is the fourth most common malignancy in males. It can present across the whole continuum of severity, from mild through...
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Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapy
BackgroundCell therapy provides hope for treatment of advanced liver failure. Proliferating human hepatocytes (ProliHHs) were derived from primary...
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Endophytic N2 fixation in sweet potato: responses to N, P, and K inputs and visualization of 15N2 utilizing bacterial cells via Raman spectroscopy
Fertilizer-N strongly limits non-leguminous crop yields; however, sweet potato ( Ipomoea batatas ) is an exception, likely due to its ability to...
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Photochemical synthesis of pink silver and its use for monitoring peptide nitration via surface enhanced Raman spectroscopy (SERS)
Oxidative stress may cause extended tyrosine posttranslational modifications of peptides and proteins. The 3-nitro-L-tyrosine (Nit), which is...
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Raman spectroscopy for real-time and in situ monitoring of mechanochemical milling reactions
Solid-state milling has emerged as an alternative, sustainable approach for preparing virtually all classes of compounds and materials. In situ...
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Raman spectroscopy enables phenoty** and assessment of nutrition values of plants: a review
Our civilization has to enhance food production to feed world’s expected population of 9.7 billion by 2050. These food demands can be met by...
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Raman imaging of Micrasterias: new insights into shape formation
The algae Micrasterias with its star-shaped cell pattern is a perfect unicellular model system to study morphogenesis. How the indentations are...
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Identification of inflammatory markers in eosinophilic cells of the immune system: fluorescence, Raman and CARS imaging can recognize markers but differently
Eosinophils (Eos) play an important role in the immune system’s response releasing several inflammatory factors and contributing to allergic...
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Mössbauer and Raman characterization of iron-loaded woody charcoal: effects of Fe3+-dispersion in wood on reduction of Fe3+ and graphitization in carbonization
An Fe 3+ -impregnation method was improved to disperse Fe 3+ in wood powder more homogeneously, and the wood powder was carbonized at various...
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Biochemical changes in the cytoplasm of bovine oocytes during the in vitro maturation process: a Raman microscopy study
The sequence and chronology of the main biochemical changes occurring in the cytoplasm of bovine oocytes during the in vitro maturation process were...
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Microbial phenomics linking the phenotype to function: The potential of Raman spectroscopy
Raman spectroscopy is a promising tool for identifying microbial phenotypes based on single cell Raman spectra reflecting cellular biochemical...
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Genetic architecture and genomic selection of fatty acid composition predicted by Raman spectroscopy in rainbow trout
BackgroundIn response to major challenges regarding the supply and sustainability of marine ingredients in aquafeeds, the aquaculture industry has...
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The effects of short term hyperglycemia on human red blood cells studied using Raman spectroscopy and optical trap
Management of postprandial hyperglycemia is important for preventing severe complications like cardiovascular disease in diabetes patients. The...
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Multimodal, label-free fluorescence and Raman imaging of amyloid deposits in snap-frozen Alzheimer’s disease human brain tissue
Alzheimer’s disease (AD) neuropathology is characterized by hyperphosphorylated tau containing neurofibrillary tangles and amyloid-beta (Aβ) plaques....