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Physical dynamic double-network hydrogels as dressings to facilitate tissue repair
Double-network hydrogels can be tuned to have high mechanical strength, stability, elasticity and bioresponsive properties, which can be combined to...
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Tissue-Engineered 3D In Vitro Disease Models for High-Throughput Drug Screening
During high-throughput drug screening, in vitro models are fabricated and the effects of therapeutics on the models evaluated in high throughput—for...
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An Insight of Nanomaterials in Tissue Engineering from Fabrication to Applications
Tissue engineering is a research domain that deals with the growth of various kinds of tissues with the help of synthetic composites. With the...
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Development and Implementation of Portable Biosensors in Microfluidic Point-of-Care Devices for Pathogen Detection
Massive pathological outbreaks have frequently impacted global risk, emphasizing the necessity for on-site sample analysis techniques that are rapid,...
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Application of Ultrasound to Enhancing Stem Cells Associated Therapies
Pluripotent stem cell therapy exhibits self-renewal capacity and multi-directional differentiation potential and is considered an important...
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Photosensitive hydrogels: from structure, mechanisms, design to bioapplications
Hydrogel is a smart material with a three-dimensional network structure and has been widely used in various fields due to its good biodegradability,...
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Successful Stories of 3D Printing in Healthcare Applications: A Brief Review
3D printing is extensively being used, nowadays, for mass customization and fabrication of complex products with different shape, size, and...
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Stem Cells and Hydrogels for Liver Tissue Engineering: Synergistic Cure for Liver Regeneration
The liver is one of the body’s tissues that has regenerative abilities. But if the damage is too much, it needs to medical interventions for the...
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See-N-Seq: RNA sequencing of target single cells identified by microscopy via micropatterning of hydrogel porosity
Single cell RNA sequencing has the potential to elucidate transcriptional programs underlying key cellular phenotypes and behaviors. However, many...
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Induction of Corneal Epithelial Differentiation of Induced Pluripotent and Orbital Fat-Derived Stem Cells Seeded on Decellularized Human Corneas
Up to 40% of donor corneas are deemed unsuitable for transplantation, aggravating the shortage of graft tissue. In most cases, the corneal...
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Surface Creasing-Induced Micropatterned GelMA Using Heating-Hydration Fabrication for Effective Vascularization
BackgroundSurface modification is used to modify the biomaterials for the regulation of cell culture using different approaches, such as chemical...
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Automated Functional Screening for Modulators of Optogenetically Activated Neural Responses in Living Organisms
All-optical methods of probing in vivo brain function are advantageous for their compatibility with automated microscopy and fast spatial targeting...
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Natural Products and Nanopharmaceuticals
Drug discovery has faced many challenges, and the diversity of natural products offers a huge number of opportunities for new drug findings. Most of...
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Wearable sensors for monitoring marine environments and their inhabitants
Human societies depend on marine ecosystems, but their degradation continues. Toward mitigating this decline, new and more effective ways to...
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Molecular targets and therapeutic strategies for triple-negative breast cancer
Triple-negative breast cancer (TNBC) is known for its heterogeneous complexity and is often difficult to treat. TNBC lacks the expression of major...
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Myocardial Fibrosis: Cell Signaling and In Vitro Modeling
Heart disease is the leading cause of death in the US and worldwide. In addition to alterations in cardiomyocyte structure and cellular composition,...
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In vivo restoration of dystrophin expression in mdx mice using intra-muscular and intra-arterial injections of hydrogel microsphere carriers of exon skip** antisense oligonucleotides
Duchenne muscular dystrophy (DMD) is a genetic disease caused by a mutation in the X-linked Dytrophin gene preventing the expression of the...
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Biomatrices for Heart Regeneration and Cardiac Tissue Modelling In Vitro
Cardiac muscle is the hardest working muscle in the body, pum** approximately 70 g of blood with every heartbeat, circulating 9500 l of blood daily...
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Three-dimensional human neural culture on a chip recapitulating neuroinflammation and neurodegeneration
Neuroinflammation has either beneficial or detrimental effects, depending on risk factors and neuron–glia interactions in neurological disorders....
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Bioprinting
Since the discovery of cells in 1665 by Robert Hooke, they are considered nature’s building blocks that are primarily responsible for giving us a...