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Activity-Based Screening of Metagenomic Fosmid Libraries for Hydrogen-Uptake Enzymes
Here, we outline how to identify hydrogenase enzymes from metagenomic fosmid libraries through an activity-based screening approach. A metagenomic...
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Basics of the Molecular Biology: From Genes to Its Function
The discipline of molecular biology primarily delineates by unravelling the interactions between deoxyribonucleic acid, ribonucleic acid and proteins...
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The Effects of the Hydrogen Sulfide Donor GYY4137 on the Proteasome Pool of Colorectal Cancer Cells
Abstract —Cancer cells are characterized by an increased level of metabolism and are highly dependent on the correct functioning of the processes that...
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11th International Conference on “Photosynthesis and Hydrogen Energy Research for Sustainability”
All aerobic life on Earth depends on oxygenic photosynthesis, occurring in both prokaryotic and eukaryotic organisms. This process can be divided...
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Design anticancer potential of Zn(II)isoleucinedithiocarbamate complex on MCF-7 cell lines: synthesis, characterization, molecular docking, molecular dynamic, ADMET, and in-vitro studies
Cisplatin is a cancer medication widely used today, but it still poses some problems due to its toxic properties in the body. To overcome this issue,...
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Identification of potential PIM-2 inhibitors via ligand-based generative models, molecular docking and molecular dynamics simulations
Proviral Integrations of Moloney-2 (PIM-2) kinase is a promising target for various cancers and other diseases, and its inhibitors hold potential for...
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Molecular Dynamics Simulations of Chemically Modified Ribonucleotides
Post-transcriptional modifications are crucial for RNA function, with roles ranging from the stabilization of functional RNA structures to modulation...
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Molecular mechanism of muscarinic acetylcholine receptor M3 interaction with Gq
Muscarinic acetylcholine receptor M3 (M3) and its downstream effector Gq/11 are critical drug development targets due to their involvement in...
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Molecular dynamics study of the competitive binding of hydrogen peroxide and water molecules with DNA phosphate groups
The interaction of hydrogen peroxide molecules with the DNA double helix is of great interest for understanding the mechanisms of anticancer therapy...
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Towards new bioactive fluorine-containing 1,3,4-oxadiazole-amide derivatives: synthesis, antibacterial activity, molecular docking and molecular dynamics simulation study
Through the approach of molecular hybridization, this study rationally designed and synthesized new trifluoromethyl-1,3,4-oxadiazole amide...
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Hydrogen-rich water improvement in root growth in maize exposed to saline stress
Hydrogen gas (H 2 ) is a newly discovered signaling molecule involved in stress response of plants. This study investigated physiological and molecular...
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Encapsulating and stabilizing enzymes using hydrogen-bonded organic frameworks
Enzymes are outstanding natural catalysts with exquisite 3D structures, initiating countless life-sustaining biotransformations in living systems....
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Design, Synthesis, and Molecular Docking of a Novel Pyrimidine Terminal Alkyne Antitumor Agent
AbstractFive compounds were successfully synthesized through several simple steps. Alkynyl plays an indispensable role in the structural modification...
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In silico screening of Fyn kinase inhibitors using classification-based QSAR model, molecular docking, molecular dynamics and ADME study
This study aimed to use a computational approach that combined the classification-based QSAR model, molecular docking, ADME studies, and molecular...
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Molecular responses of higher plants to dehydration
A massive amount of data has been accumulating on the molecular responses of plants to water deficit. In plants, dehydration activates a protective...
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A Review on Hydrogen Production from Biomass and Commercialization Assessment Through Technology Readiness Levels (TRLs)
In the current condition, hydrogen energy has the potential to be a sustainable fuel for the future as energy becomes more important every day. As...
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Protein-Protein Interaction Studies Using Molecular Dynamics Simulation
Protein-protein interactionProtein-protein interaction (PPI) is a crucial event for many biological functions. Studying the molecular details of PPI...
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Dietary selection of metabolically distinct microorganisms drives hydrogen metabolism in ruminants
Ruminants are important for global food security but emit the greenhouse gas methane. Rumen microorganisms break down complex carbohydrates to...
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Hydrogen Peroxide and Its Role in Abiotic Stress Tolerance in Plants
Plants are continuously subjected to numerous abiotic stresses such as heavy metal, salinity, drought, high temperature, cold and ozone etc. which...
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Quantum chemical studies on hydrogen bonds in helical secondary structures
We present a brief review of our recent computational studies of hydrogen bonds (H-bonds) in helical secondary structures of proteins, α-helix and 3 10 ...
