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The genomic diversification of grapevine clones
BackgroundVegetatively propagated clones accumulate somatic mutations. The purpose of this study was to better appreciate clone diversity and...
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First insights into the complete mitochondrial genome of a deep-sea eel Congriscus megastoma (Anguilliformes, Congroidei, Congridae): characterization and phylogenetic inference
The complete mitochondrial DNA sequence of a deep-sea eel Congriscus megastoma (Anguilliformes: Congridae) was determined by high throughput...
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Emerging Threats of Exotic Viruses to the Oman Agriculture: Diversity and Management Strategies
The Sultanate of Oman holds territory in the region of the Arabian Peninsula that is located in the South East. Oman has an extensive track record of...
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Development of a 2-hydroxyglutarate production system by Corynebacterium glutamicum
Abstract2-Oxoglutarate (2-OG) is a tricarboxylate cycle intermediate that can be biologically converted into several industrially important...
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Analysis of the leaf metabolome in Arabidopsis thaliana mutation accumulation lines reveals association of metabolic disruption and fitness consequence
Understanding the mechanisms by which mutations affect fitness and the distribution of mutational effects are central goals in evolutionary biology....
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Comparative genomics identifies thousands of candidate structured RNAs in human microbiomes
BackgroundStructured RNAs play varied bioregulatory roles within microbes. To date, hundreds of candidate structured RNAs have been predicted using...
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In silico prospecting of the mtDNA of Macrobrachium amazonicum from transcriptome data
BackgroundMacrobrachium amazonicum is a freshwater prawn widely distributed in South America that is undergoing speciation, so the denomination “ M....
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Complete chloroplast genome sequences of the ornamental plant Prunus cistena and comparative and phylogenetic analyses with its closely related species
BackgroundPrunus cistena is an excellent color leaf configuration tree for urban landsca** in the world, which has purplish red leaves, light pink...
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Molecular Techniques for Root-Knot Nematode Identification
Among plant-parasitic nematodes, root-knot nematodes (RKN), Meloidogyne spp., are the most important parasite infecting economically important crops...
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Evidence for widespread existence of functional novel and non-canonical human transcripts
BackgroundFraction of functional sequence in the human genome remains a key unresolved question in Biology and the subject of vigorous debate. While...
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Whole-genome sequencing and variant discovery of Citrus reticulata “Kinnow” from Pakistan
Citrus is a source of nutritional and medicinal advantages, cultivated worldwide with major groups of sweet oranges, mandarins, grapefruits,...
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Experimental characterization of de novo proteins and their unevolved random-sequence counterparts
De novo gene emergence provides a route for new proteins to be formed from previously non-coding DNA. Proteins born in this way are considered random...
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Systematically identifying genetic signatures including novel SNP-clusters, nonsense variants, frame-shift INDELs, and long STR expansions that potentially link to unknown phenotypes existing in dog breeds
BackgroundIn light of previous studies that profiled breed-specific traits or used genome-wide association studies to refine loci associated with...
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Complete chloroplast genome sequence and variation analysis of Brassica oleracea L.
Cabbage ( Brassica oleracea L. var capitata ), belonging to the Cruciferae family, is among the most widely produced and consumed vegetables in China....
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Detecting genetic epistasis by differential departure from independence
Countering prior beliefs that epistasis is rare, genomics advancements suggest the other way. Current practice often filters out genomic loci with...
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ddRADseq-mediated detection of genetic variants in sugarcane
Key messageThe article presents an optimization of the key parameters for the identification of SNPs in sugarcane using a GBS protocol based on two...
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DNA methylation-calling tools for Oxford Nanopore sequencing: a survey and human epigenome-wide evaluation
BackgroundNanopore long-read sequencing technology greatly expands the capacity of long-range, single-molecule DNA-modification detection. A growing...
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Dissecting chickpea genomic loci associated with the root penetration responsive traits in compacted soil
Main conclusionSoil compaction reduces root exploration in chickpea. We found genes related to root architectural traits in chickpea that can help...
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Chromatin accessibility profiling in Neurospora crassa reveals molecular features associated with accessible and inaccessible chromatin
BackgroundRegulation of chromatin accessibility and transcription are tightly coordinated processes. Studies in yeast and higher eukaryotes have...
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MalariaSED: a deep learning framework to decipher the regulatory contributions of noncoding variants in malaria parasites
Malaria remains one of the deadliest infectious diseases. Transcriptional regulation effects of noncoding variants in this unusual genome of malaria...
