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Silencing of juvenile hormone epoxide hydrolase gene in Spodoptera litura (Lepidoptera: Noctuidae) by oral delivery of double-stranded RNA
Spodoptera litura being polyphagous is the major constraints for the production of many agricultural crops. The extensive use of insecticides for its...
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The Next Generation of Drug Delivery: Harnessing the Power of Bacteriophages
The use of biomaterials, such as bacteriophages, as drug delivery vehicles (DDVs) has gained increasing interest in recent years due to their... -
MicroRNA delivery based on nanoparticles of cardiovascular diseases
Cardiovascular disease, especially myocardial infarction, is a serious threat to human health. Many drugs currently used cannot achieve the desired...
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Convenient synthesis and delivery of a megabase-scale designer accessory chromosome empower biosynthetic capacity
Synthetic biology confers new functions to hosts by introducing exogenous genetic elements, yet rebuilding complex traits that are based on...
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Peptide Nanoparticles for Gene Packaging and Intracellular Delivery
Efficient gene transfer is necessary for advanced biotechnologies ranging from gene therapy to synthetic biology. Peptide nanoparticles provide... -
Novel Delivery Methods for CRISPR-Based Plant Genome Editing
Using modern genome editing tools, scientists are increasingly able to engineer animals and plants for better traits and improved downstream outcomes... -
Gene Therapy
The gene with the expression vector is inserted in the organ, which needs to be repaired. The gene is expressed locally in the area and recombinant... -
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Nanoparticle-mediated dsRNA delivery for precision insect pest control: a comprehensive review
Nanoparticle-based delivery systems have emerged as powerful tools in the field of pest management, offering precise and effective means of...
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Progress of cationic gene delivery reagents for non-viral vector
Gene delivery systems play a vital role in gene therapy and recombinant protein production. The advantages of using gene delivery reagents for...
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Drug delivery strategies for antibiofilm therapy
Although new antibiofilm agents have been developed to prevent and eliminate pathogenic biofilms, their widespread clinical use is hindered by poor...
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Construction of a bacteriophage-derived vector with potential applications in targeted drug delivery and cell imaging
There is a strong relationship between the dysregulation of epidermal growth factor receptor (EGFR) and the development of epithelial-derived...
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Drug Delivery Systems for Tissue Engineering
Drug delivery systemsDrug delivery systems (DDSs) are developed having in view the need to control the dose (within the therapeuticTherapeutic... -
Association between vaginal microbiome alteration and povidone iodine use during delivery
BackgroundThe vaginal microbiome is a dynamic community of microorganisms in the vagina. Its alteration may be influenced by multiple factors,...
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Preparation of UiO-66 loaded Letrozole nano-drug delivery system: enhanced anticancer and apoptosis activity
The use of drug delivery systems in targeting and achieving the targeting of drugs in treating diseases, especially cancer, has attracted the...
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Biomanufacturing Aspects of Gene Therapy
The notion that genetic material could be transferred to a host patient for therapeutic benefit has been around for over half a century. However, it... -
Surfactants as a Means of Delivering a Reporter Genetic Construct Based on Binase Suicide Gene to Tumor Cells
AbstractObjective: Among modern gene therapy methods for combating oncology, suicidal gene therapy based on the delivery of a cytotoxic agent to...
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In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy
The prognosis of lung metastatic osteosarcoma (OS) remains disappointing. siRNA-based gene silencing of VEGFR2 is a promising treatment strategy for...
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Delivered complementation in planta (DCIP) enables measurement of peptide-mediated protein delivery efficiency in plants
Using a fluorescence complementation assay, Delivered Complementation in Planta (DCIP), we demonstrate cell-penetrating peptide-mediated cytosolic...
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CRISPR Gene Editing of Hematopoietic Stem and Progenitor Cells
Genetic editing of hematopoietic stem and progenitor cells can be employed to understand gene-function relationships underlying hematopoietic cell...