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Bacterial Microarrays for Examining Bacterial Glycosignatures and Recognition by Host Lectins
The surface of bacteria displays diverse carbohydrate structures that may significantly differ among bacteria with the same cell wall architecture...
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Recombinant production and characterisation of two chitinases from Rasamsonia emersonii, and assessment of their potential industrial applicability
Rasamsonia emersonii (previously Talaromyces emersonii ) is a thermophilic filamentous fungus displaying optimum growth at 45 °C. It has a history of...
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PACmn for improved optogenetic control of intracellular cAMP
BackgroundCyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger that transduces extracellular signals in virtually all eukaryotic...
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Effect of glycosylation on the affinity of the MTB protein Ag85B for specific antibodies: towards the design of a dual-acting vaccine against tuberculosis
BackgroundTo create a dual-acting vaccine that can fight against tuberculosis, we combined antigenic arabino-mannan analogues with the Ag85B protein....
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Seed-Based Production of Recombinant Proteins
The use of plants to produce recombinant proteins has become a promising alternative to current expression systems based on microorganisms and cell...
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Herbometallic nano-drug inducing metastatic growth inhibition in breast cancer through intracellular energy depletion
AbstractCancer cells need extensive energy supply for their uncontrolled cell division and metastasis which is exclusively dependent on neighboring...
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A Short Review of Advances in Plant-Based Antigen Production Strategies and the Production of Viral Vaccine Antigens Derived from CRISPR/Cas9 Genome Edited N. benthamiana Plants for Enhanced Vaccine Efficacy
Plant-based antigen manufacturing procedures have transformed vaccine research and industry by offering a cost-effective, scalable, and safe...
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Signaling domains of cancer-associated glycolipids
Immunotherapy of malignant cancers is now becoming one of representative approaches to overcome cancers. To construct strategies for immunotherapy,...
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The interplay of mitophagy, autophagy, and apoptosis in cisplatin-induced kidney injury: involvement of ERK signaling pathway
AKI induced by CP chemotherapy remains an obstacle during patient treatments. Extracellular signal-regulated protein kinases 1/2 (ERK), key...
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Elucidation of the K32 Capsular Polysaccharide Structure and Characterization of the KL32 Gene Cluster of Acinetobacter baumannii LUH5549
Capsular polysaccharide (CPS), isolated from Acinetobacter baumannii LUH5549 carrying the KL32 capsule biosynthesis gene cluster, was studied by...
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Glycans in autophagy, endocytosis and lysosomal functions
Glycans have been shown to function as versatile molecular signals in cells. This prompted us to look at their roles in endocytosis, endolysosomal...
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Amnio acid substitution at position 298 of human glucose-6 phosphatase-α significantly impacts its stability in mammalian cells
Glucose-6-phosphatase-α (G6Pase-α) catalyzes the hydrolysis of glucose-6-phosphate to glucose and functions as a key regulator in maintaining blood...
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ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner
SARS-CoV-2 has evolved continuously and accumulated spike mutations with each variant having a different binding for the cellular ACE2 receptor. It...
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Historical Overview of Integrated GAG-omics and Proteomics
The ECM is a complex molecular network that surrounds all cells and consists of proteins, glycoproteins, hyaluronan, glycosaminoglycans (GAGs), and...
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Metabolomics and transcriptomics based multi-omics integration reveals radiation-induced altered pathway networking and underlying mechanism
Recent advancement in integrated multi-omics has significantly contributed to many areas of the biomedical field. Radiation research has also grasped...
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Fish Lectins in Host–Pathogen Interaction
Host–pathogen interactions are complex, governed by numerous factors such as host’s age, environment, behavior, immune system, and characteristics of...
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Protein carbonylation in food and nutrition: a concise update
Protein oxidation is a topic of indisputable scientific interest given the impact of oxidized proteins on food quality and safety. Carbonylation is...
