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Potential of the enzyme laccase for the synthesis and derivatization of antimicrobial compounds
Laccases [E.C. 1.10.3.2, benzenediol:dioxygen oxidoreductase] can oxidize phenolic substances, e.g. di- and polyphenols, hydroxylated biaryls,...
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The monocyte to high-density lipoprotein cholesterol ratio is a risk factor for frequent premature ventricular complexes: a retrospective cohort study
BackgroundLittle is known about the link between the monocyte to high-density lipoprotein cholesterol ratio (MHR) and frequent premature ventricular...
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Pd(NHC)(cinnamyl)Cl-catalyzed Suzuki cross-coupling reaction of aryl sulfonates with arylboronic acids
AbstractA series of N -heterocyclic carbene (NHC)–palladium catalysts have been synthesized and applied to catalyze the Suzuki coupling reaction...
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Controlled electron transfer by molecular wires embedded in ultrathin insulating membranes for driving redox catalysis
Organic bilayers or amorphous silica films of a few nanometer thickness featuring embedded molecular wires offer opportunities for chemically...
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Data-driven multiscale modeling reveals the role of metabolic coupling for the spatio-temporal growth dynamics of yeast colonies
BackgroundMulticellular entities like mammalian tissues or microbial biofilms typically exhibit complex spatial arrangements that are adapted to...
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A competing-risks model explains hierarchical spatial coupling of measles epidemics en route to national elimination
Apart from its global health importance, measles is a paradigm for the low-dimensional mechanistic understanding of local nonlinear population...
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Coupling fossil records and traditional discrimination metrics to test how genetic information improves species distribution models of the European beech Fagus sylvatica
Species distribution models (SDMs) are widely used to hindcast or forecast suitable habitat conditions during climate change. Although distant...
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Preparation and sustained-release study of Litsea cubeba essential oil inclusion complex with γ-cyclodextrin-metal–organic frameworks
BackgroundLitsea cubeba essential oil (LCEO) is a food additive that requires encapsulation to delay its release due to its irritating nature. To...
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Three new amide derivatives from the fungus Alternaria brassicicola
Three new amide derivatives (alteralkaloids A–C, 1 – 3 ) and three known alkaloids ( 4 – 6 ) were afforded after phytochemical investigation of fungus Alterna...
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The S-component fold: a link between bacterial transporters and receptors
The processes of nutrient uptake and signal sensing are crucial for microbial survival and adaptation. Membrane-embedded proteins involved in these...
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The Skeletal Muscle Calcium Channel
CaV1.1 is the voltage-gated calcium channel isoform uniquely expressed in skeletal muscle. Its primary function is that of the voltage sensor for...
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Normal Fluctuations of Biological Membrane Shape as a Coupling Factor for Ordered Monolayer Domains
AbstractIt is believed that separation of lipid matrix of biological membranes into ordered and disordered phases plays an important role in the...
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Integration of metabolic and signaling networks
This contribution addresses the construction of mathematical models that provide a combined description of metabolic and regulatory processes within...
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Integrative Mathematical Model of Electrical, Metabolic and Mechanical Processes in Human Cardiomyocytes
AbstractA complex sequence of electrical and mechanical processes at different levels of the heart organization provides its pum** function. The...
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Climate-Sensitive Urban Design for Thermal Comfort
Urban and microclimate have an intense relationship that affects each other. The specific urban structure can affect microclimate because of the high...
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Hordatines, dimerised hydroxycinnamoylagmatine conjugates of barley (Hordeum vulgare L.): an appraisal of the biosynthesis, chemistry, identification and bioactivities
Hydroxycinnamoylamides are specialised metabolites widely distributed in the plant kingdom. These are phenolic moieties covalently linked to mono- or...
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Extreme conditions affect neuronal oscillations of cerebral cortices in humans in the China Space Station and on Earth
Rhythmical oscillations of neural populations can reflect working memory performance. However, whether neuronal oscillations of the cerebral cortex...
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Probing the allosteric NBD-TMD crosstalk in the ABC transporter MsbA by solid-state NMR
The ABC transporter MsbA plays a critical role in Gram-negative bacteria in the regulation of the outer membrane by translocating core-LPS across the...
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A data-driven network decomposition of the temporal, spatial, and spectral dynamics underpinning visual-verbal working memory processes
The brain dynamics underlying working memory (WM) unroll via transient frequency-specific large-scale brain networks. This multidimensionality (time,...
