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The overexpression of SlBRI1 driven by Atrd29A promoter-transgenic plants improves the chilling stress tolerance of tomato
Main conclusionOverexpression of SlBRI1 driven by the Atrd29A promoter could increase the cold resistance of tomato plants during chilling stress but...
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msBERT-Promoter: a multi-scale ensemble predictor based on BERT pre-trained model for the two-stage prediction of DNA promoters and their strengths
BackgroundA promoter is a specific sequence in DNA that has transcriptional regulatory functions, playing a role in initiating gene expression....
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Rice WRKY13 TF protein binds to motifs in the promoter region to regulate downstream disease resistance-related genes
In plants, pathogen resistance is brought about by the binding of certain transcription factor (TF) proteins to the cis -elements of certain target...
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Temporal Control of Promoter Activity During the Caulobacter Cell Cycle
A cascade of cellular events must occur to allow cells to complete one round of cell division. Such a successful cell division cycle relies on the... -
Evaluation of cucumber UBL5 promoter as a tool for transgene expression and genome editing in plants
Transgene expression and genome editing can help improve cucumber varieties to better respond to climate change. This study aimed to evaluate the...
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Intra-promoter switch of transcription initiation sites in proliferation signaling-dependent RNA metabolism
Global changes in transcriptional regulation and RNA metabolism are crucial features of cancer development. However, little is known about the role...
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Repressible Promoter System to Study Essential Genes in Mycobacteria
Inducible gene expression systems represent powerful tools for studying essential gene function and for validation of drug targets in bacteria. Even... -
A Guide to MethylationToActivity: A Deep Learning Framework That Reveals Promoter Activity Landscapes from DNA Methylomes in Individual Tumors
Genome-wide DNA methylomes have contributed greatly to tumor detection and subclassification. However, interpreting the biological impact of the DNA... -
Improving yield-related traits by editing the promoter of the heading date gene Ehd1 in rice
Key messageWe developed an efficient promoter editing method to create different weak Ehd1 alleles in elite japonica rice variety ZJ8 with slightly...
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Functional characterization of GhNAC2 promoter conferring hormone- and stress-induced expression: a potential tool to improve growth and stress tolerance in cotton
The GhNAC2 transcription factor identified from G. herbaceum improves root growth and drought tolerance through transcriptional reprogramming of...
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Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy
During formation of the transcription-competent open complex (RPo) by bacterial RNA polymerases (RNAPs), transient intermediates pile up before...
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G-quadruplex structural dynamics at MAPK12 promoter dictates transcriptional switch to determine stemness in breast cancer
P38γ (MAPK12) is predominantly expressed in triple negative breast cancer cells (TNBC) and induces stem cell (CSC) expansion resulting in decreased...
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Promoter variations of ClERF1 gene determines flesh firmness in watermelon
BackgroundFlesh firmness is a critical factor that influences fruit storability, shelf-life and consumer’s preference as well. However, less is known...
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A nematode-inducible promoter can effectively drives RNAi construct to confer Meloidogyne incognita resistance in tomato
Key messageHeterologous expression of a nematode-responsive promoter in tomato successfully driven the RNAi constructs to impart root-knot nematode...
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Promoter of Nitrate Reductase Gene Behaves Differently Under Salinity Stress in Contrasting Rice Genotype
Soil salinity is a global agricultural issue that decreases both plant production and survival. Plants synthesize secondary nitrogen metabolites,...
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CDKN2A promoter methylation enhances self-renewal of glioblastoma stem cells and confers resistance to carmustine
BackgroundGlioblastoma, a highly aggressive form of brain cancer, poses significant challenges due to its resistance to therapy and high recurrence...
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Cloning and functional analysis of the promoter of a UDP-glycosyltransferase gene from Panax quinquefolium L.
Pq3-O-UGT2 is a key UDP-glycosyltransferase gene in the ginsenoside biosynthesis pathway of Panax quinquefolium L. Functional analysis of promoter...
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Identification and validation of chickpea (Cicer arietinum L.) Isoflavone synthase 1 (CaIfs1) promoter conferring pathogen-induced expression
Chickpea ( Cicer arietinum L.) is the third most economically important food legume in the world. Its production is severely hampered by diseases and...
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Identification of a novel promoter region responsible for the embryo-specific expression of SERK1 in pineapple
Somatic embryogenesis (SE) is a key regeneration process in plant. AcSERK1 is a gene specifically expressed in the early stage of SE in pineapple ( Ana...
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PSG076 Promoter Shows Late Pollen-Specific Activity in Wheat (Triticum aestivum L.)
Pollen, as the male gametophyte of plants, plays a critical role in plant sexual reproduction. Investigating pollen-specific promoters not only helps...