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Heat shock protein HvHSP16.9 from wild barley enhances tolerance to salt stress
Heat shock proteins ( HSP s) are known to play a crucial role in the response of plants to environmental stress, particularly heat stress....
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Heat Shock Proteins in Fish Health Management
All types of cells, including those of bacteria and mammals, include a group of highly conserved proteins called heat shock proteins. They play a... -
Hsp70/Hsp90 Organising Protein (Hop): Coordinating Much More than Chaperones
The Hsp70/Hsp90 organising protein (Hop, also known as stress-inducible protein 1/STI1/STIP1) has received considerable attention for diverse... -
Heat shock protein HSPA13 promotes hepatocellular carcinoma progression by stabilizing TANK
HSPA13, an important member of the heat shock protein family, plays an essential role in the oncogenesis of many organs, but the mechanism and...
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Analysis of the transcriptome and heat-shock protein (HSP) family expression in the spikelets of hulless oat (Avena sativa L.) under heat stress
Oat is an economically important cereal crop with a distinct nutritional profile, including β-glucan and avenin seed storage proteins. Despite its...
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HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC), the most prevalent type of pancreatic cancer, is one of the deadliest forms of cancer with limited therapy...
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HSP70 attenuates neuronal necroptosis through the HSP90α-RIPK3 pathway following neuronal trauma
BackgroundNecroptosis, a newly defined regulatable necrosis with membrane disruption, has been demonstrated to participate in trauma brain injury...
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Heat shock protein DNAJA2 regulates transcription-coupled repair by triggering CSB degradation via chaperone-mediated autophagy
Transcription-coupled nucleotide excision repair (TC-NER) is an important genome maintenance system that preferentially removes DNA lesions on the...
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Heat Shock Proteins as Potential Indicators of Induced Stress in Nematodes
Heat shock proteins (HSPs) in all animals studied to date constitute potential indicators of stress, under various environmental conditions. The goal... -
Role of Heat Shock Factors in Stress-Induced Transcription: An Update
Heat shock proteins (HSP) are rapidly induced after proteotoxic stresses such as heat shock and accumulate at high concentrations in cells. HSP... -
Heat Shock Proteins in Plant Protection from Oxidative Stress
Abstract—This review considers the recent progress on the role of heat shock proteins (HSPs), as well as transcription factors of heat shock proteins...
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Immunohistochemical, Flow Cytometric, and ELISA-Based Analyses of Intracellular, Membrane-Expressed, and Extracellular Hsp70 as Cancer Biomarkers
The major stress-inducible 70 kDa heat shock (stress) protein 70 (Hsp70) is frequently overexpressed in highly aggressive tumor cells and thus might... -
Structural and Functional Impacts of Extended N-Terminal End of the Small Heat Shock Protein Tpv HSP 14.3
AbstractSmall heat shock proteins (sHSPs) are composed of the α-crystallin domain, which is highly conserved, and variable N-terminal and C-terminal...
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Functional diversification of heat shock factors
Heat shock transcription factors (HSFs) are widely known as master regulators of the heat shock response. In invertebrates, a single heat shock...
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HSP70-binding motifs function as protein quality control degrons
Protein quality control (PQC) degrons are short protein segments that target misfolded proteins for proteasomal degradation, and thus protect cells...
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Hsp70 Knockdown in the Brine Shrimp Artemia franciscana: Implication on Reproduction, Immune Response and Embryonic Cuticular Structure
The potential functional role(s) of heat shock protein 70 (Hsp70) in the brine shrimp, Artemia franciscana , a crucial crustacean species for...
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Computational analyses of amino acid molecules of heat shock protein-70 for elucidating its evolutionary diversity and protein interactions in selected farm animals
BackgroundThe heat shock protein-70 (HSP70) is a protein associated with response and adaptation to stress, as well as protection of the cells...
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Monitoring of the Heat Shock Response with a Real-Time Luciferase Reporter
The heat shock response (HSR) is a cellular mechanism for counteracting acute proteotoxic stress. In eukaryotes, transcriptional activation of the... -
Proteostasis in ice: the role of heat shock proteins and ubiquitin in the freeze tolerance of the intertidal mussel, Mytilus trossulus
The bay mussel, Mytilus trossulus , is an animal that can survive extracellular ice formation. Depending on air and ocean temperatures, freeze...
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Heat shock protein 70 gene expression and stress response of red-spotted (Epinephelus akaara) and hybrid (E. akaara female × E. lanceolatus male) groupers to heat and cold shock exposure
The importance of the temperature tolerance of fish is increasing due to climate change caused by global warming. This study examined the expression...