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Genetic engineering of aminodeoxyhexose biosynthesis in Streptomyces fradiae
The antibacterial properties of macrolide antibiotics (such as erythromycin, tylosin, and narbomycin) depend ultimately on the glycosylation of...
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Influence of dimethylsulfoxide on tylosin production in Streptomyces fradiae
The polyketide aglycone, tylactone (protylonolide), does not normally accumulate during tylosin production in Streptomyces fradiae , suggesting that...
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Sweet home actinomycetes: The 1999 MDS Panlabs Lecture
For the past 25 years, I have devoted most of my research efforts to the application of molecular genetics to yield improvement and production of...
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The Structure of the Antibiotic Binding Sites in Bacterial Ribosomes
With only a few exceptions, antibiotics inhibit protein synthesis by binding to the ribosome and blocking some of the several functions that the... -
High frequency conjugal transfer of tylosin genes and amplifiable DNA in Streptomyces fradiae
Genes encoding enzymes for tylosin biosynthesis, genes involved in the expression of resistance to tylosin (Tyl), hygromycin B (Hm), chloramphenicol...
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The adsorption and release of tylosin by clays and soils
The uptake and release of tylosin by Wyoming bentonite, Ca ++ montmorillonite, illite (Fithian Illinois) and kaolin (china clay) was studied. The...
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Stoffwechselprodukte von Mikroorganismen
A cell-free extract from mycelium of Streptomyces rimosus producing the antibiotic tylosin, catalyses the formation of TDP-mycarose from TDP- d -glucose...