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Showing 21-40 of 4,111 results
  1. Nicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis

    Background

    Nonalcoholic steatohepatitis (NASH) is a prevalent chronic liver condition. However, the potential therapeutic benefits and underlying...

    **u-lian Lin, Ya-ling Zeng, ... Jian-Guo Zeng in Lipids in Health and Disease
    Article Open access 27 June 2024
  2. A New Approach to Release Insoluble Curcumin into DU-145 Human Prostate Cancer Cells Through Biodegradable Polymeric Nanocarriers with Apoptosis Induction and Metastasis Inhibition

    Abstract

    Objective: Curcumin (C 21 H 20 O 6 , CUR) is the most abundant compound in turmeric (Curcuma longa), which had antioxidant, anti-cancer and...

    Mohammad Ali Bepouei, Faten Divsar, ... Mahdi Shahriarinour in Russian Journal of Bioorganic Chemistry
    Article 05 June 2024
  3. Transcription of human β-galactoside α2,6-sialyltransferase (hST6Gal I) is downregulated by curcumin through AMPK signaling in human colon carcinoma HCT116 cells

    Background

    In this study, we observed that in human colon carcinoma HCT116 cells mRNA level of the human β-galactoside α2,6-sialyltransferase (hST6Gal...

    So-Young An, Kyoung-Sook Kim, ... Seok-Ho Kim in Genes & Genomics
    Article 25 May 2023
  4. Effect of Resveratrol and Curcumin on Changes in Fatty Acid Composition and Oxidative Stress in Liver and Kidney Tissues of Rats Exposed to 7,12-Dimethylbenz[a]anthracene (DMBA)

    Abstract

    This study was conducted for the main purpose of evaluating the effect of resveratrol and curcumin on changes in fatty acid composition in...

    Yeşim Bulut Sıltar, Ersin Demir, ... Ökkeş Yılmaz in Biology Bulletin
    Article 31 May 2024
  5. Impact of Curcumin on Hepatic Low-Density Lipoprotein Uptake

    Elevated levels of plasma low-density lipoprotein cholesterol (LDL-C) are causally related to atherosclerotic cardiovascular disease. Enhancing the...
    Mohammad Jalili-Nik, Khadijeh Mahboobnia, ... Amirhossein Sahebkar in Physical Exercise and Natural and Synthetic Products in Health and Disease
    Protocol 2022
  6. Curcumin-rich curry consumption and life expectancy: Singapore longitudinal ageing study

    The therapeutic potential of curcumin for many diseases are intensively investigated. However, real-world observational data documenting health and...

    Tze Pin Ng, Shwe Zin Nyunt, ... Keng Bee Yap in GeroScience
    Article 12 June 2023
  7. Co-treatment with bone marrow-derived mesenchymal stem cells and curcumin improved angiogenesis in myocardium in a rat model of MI

    Background

    The cardioprotective properties of mesenchymal stem cells and the therapeutic potential of curcumin (CUR) have been explored. Combining...

    Niki Mirfakhraie, Hamed Shoorei, ... Masoumeh Zirak Javanmard in Molecular Biology Reports
    Article 01 February 2024
  8. Curcumin interferes with chitin synthesis in Aedes aegypti: a computational and experimental investigation

    Throughout history, vector-borne diseases have consistently posed significant challenges to human health. Among the strategies for vector control,...

    Priyashi Rao, **al Ninama, ... Rakesh M. Rawal in Molecular Diversity
    Article 26 June 2023
  9. pH/Temperature Responsive Curcumin-Loaded Micelle Nanoparticles Promote Functional Repair after Spinal Cord Injury in Rats via Modulation of Inflammation

    Background:

    The formation of an inhibitory inflammatory microenvironment after spinal cord injury (SCI) remains a great challenge for nerve...

    Taibao Qian, Zhixiang Li, ... Yingji Mao in Tissue Engineering and Regenerative Medicine
    Article 14 August 2023
  10. Curcumin can improve spinal cord injury by inhibiting DNA methylation

    Spinal cord injury (SCI) is a serious central nervous system disease. Traumatic SCI often causes persistent neurological deficits below the injury...

    Yu Zhou, Yong Zhang, ... Xuehong Liu in Molecular and Cellular Biochemistry
    Article 19 April 2023
  11. The Role of Curcumin as an Anti-Aging Compound

    It is claimed that delaying aging is more effective and less expensive than treating specific age-related disorders. Compounds that may postpone the...
    Chenmala Karthika, Rokeya Akter, ... Sherouk Hossein Sweilam in Emerging Anti-Aging Strategies
    Chapter 2023
  12. In vitro anticancer study of novel curcumin derivatives via targeting PI3K/Akt/p53 signaling pathway

    Four new series of curcumin derivatives bearing NO-donating moiety were synthesized via etherification, nucleophilic substitution, and Knoevenagel...

    Huixian Zhou, Zhiwen Wu, ... Tao Wang in Molecular Diversity
    Article 01 July 2024
  13. Delivery of curcumin within emulsome nanoparticles enhances the anti-cancer activity in androgen-dependent prostate cancer cell

    Background

    Curcumin, a dietary polyphenol isolated from turmeric, is a potent phytochemical possessing intrinsic anticancer activities against various...

    Zeynep Busra Bolat, Zeynep Islek, ... Mehmet Hikmet Ucisik in Molecular Biology Reports
    Article 06 January 2023
  14. Synergistic anticancer effects of curcumin and crocin on human colorectal cancer cells

    Background

    Curcumin, a polyphenol compound derived from the Curcuma longa L, and crocin, a hydrophilic carotenoid from Crocus Sativus Linnaeus, are...

    Seyed Samad Hosseini, Robab Zare Reihani, ... Ahad Mokhtarzadeh in Molecular Biology Reports
    Article 21 August 2022
  15. Effects of Juglone and Curcumin Administration on Expression of FABP5 and FABP9 in MCF-7 and MDA-MB-231 Breast Cancer Cell Lines

    Abstract

    Among natural chemopreventive agents, polyphenol curcumin and naphthoquinone juglone, which has broad-spectrum anticancer activity, are...

    Article 29 March 2023
  16. Harnessing the combined effect of antivirulence agent trans-chalcone with bactericidal curcumin against sortase A enzyme to tackle Gram-positive bacterial infections

    Gram-positive bacteria are responsible for a wide range of infections in humans. In most Gram-positive bacteria, sortase A plays a significant role...

    Poonam Kumari, Sanjay K. Banerjee, ... Utpal Mohan in Folia Microbiologica
    Article 06 November 2023
  17. A fabricated hydrogel of hyaluronic acid/curcumin shows super-activity to heal the bacterial infected wound

    High risk of acute morbidities and even mortality from expanding the antibiotics resistant infectious wounds force indefinite efforts for development...

    Maryam Khaleghi, Fakhri Haghi, ... Dina Morshedi in AMB Express
    Article Open access 10 March 2023
  18. The evaluation of chitosan hydrogel based curcumin effect on DNMT1, DNMT3A, DNMT3B, MEG3, HOTAIR gene expression in glioblastoma cell line

    Background

    Cancer is one of the most important causes of death worldwide. Some types of cancer, including glioblastoma, with a high potential for...

    Sanaz Abolfathi, Maryam Zare in Molecular Biology Reports
    Article 03 June 2023
  19. Nutritional and ameliorative effects of dietary curcumin and its nano-silica and nano-zeolite encapsulated forms on growth, biochemical and fatty acid profile of common carp (Cyprinus carpio)

    The present study aimed to examine individual nutritional and ameliorative effects of silica nanoparticles (SiO 2 NPs) and natural zeolite...

    Shadieh Moradi, Samyar Ashouri, ... Edris Ghaderi in Fish Physiology and Biochemistry
    Article 12 June 2023
  20. Olive oil nanoemulsion containing curcumin: antimicrobial agent against multidrug-resistant bacteria

    Abstract

    The present work aimed to develop, characterize, and evaluate the antibacterial and antibiofilm activity of two nanoemulsions (NEs)...

    Maine Virgínia Alves Confessor, Maria Anndressa Alves Agreles, ... Isabella Macário Ferro Cavalcanti in Applied Microbiology and Biotechnology
    Article Open access 27 February 2024
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