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NADPH oxidase mediated oxidative stress signaling in FLT3-ITD acute myeloid leukemia
The internal tandem duplication of the juxtamembrane domain of the FMS-like tyrosine kinase 3 (FLT3-ITD) is the most common genetic change in acute...
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Investigating the role of itaconate in macrophage activation and oxidative stress injury in sepsis-associated acute kidney injury
BackgroundSepsis may be linked to oxidative stress and can be controlled by itaconate, an activator of the nuclear factor erythroid 2-related factor...
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Tank color influences the response of tomato clownfish (Amphiprion frenatus) to an acute stress challenge
The trade of aquarium organisms is growing worldwide. This market depends on a continuous supply of healthy and colorful aquatic animals, but this...
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STING contributes to lipopolysaccharide-induced tubular cell inflammation and pyroptosis by activating endoplasmic reticulum stress in acute kidney injury
Recently, innate immunity and inflammation were recognized as the key factors for acute kidney injury (AKI) caused by sepsis, which is closely...
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Disturbance of oxidation/antioxidant status and histopathological damage in tsinling lenok trout under acute thermal stress
The tsinling lenok trout ( Brachymystax Lenok tsinlingensis ) is a typical land-locked cold salmon. In this study, through the acute high temperature...
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Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia
BackgroundThe Proteolipid Protein 2 (PLP2), a protein in the Endoplasmic Reticulum (ER) membrane, has been reported to be highly expressed in various...
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Cofilin-1 induces acute kidney injury via the promotion of endoplasmic reticulum stress-mediated ferroptosis
Ischemia–reperfusion injury (IRI) leads to acute kidney injury (AKI), which poses serious threat to public health and society. Many clinical studies...
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Acute Salinity Stress Disrupts Gut Microbiota Homeostasis and Reduces Network Connectivity and Cooperation in Razor Clam Sinonovacula constricta
Accumulating evidence demonstrates that it is of great importance to maintain a stable and functional gut microbial community for host’s growth and...
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Pioglitazone ameliorates ischemia/reperfusion-induced acute kidney injury via oxidative stress attenuation and NLRP3 inflammasome
Acute kidney injury (AKI) induced by renal ischemia/reperfusion injury (IRI) is a severe clinical condition. ROS accumulation, antioxidant pathways...
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Responses of riparian plant roots to acute combined nitrogen and phosphorus stress: changes in root morphology and antioxidant system
Riparian plants are vulnerable to acute combined nitrogen (N) and phosphorus (P) stress induced by water quality fluctuations. Here, we carried out...
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MicroRNA qPCR normalization in Nile tilapia (Oreochromis niloticus): Effects of acute cold stress on potential reference targets
The Nile tilapia ( Oreochromis niloticus ) is one of the most important cultured fish worldwide, but tilapia culture is largely affected by low...
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The Effect of a Lipid Extract from the Marine Green Algae Codium fragile (Suringar) Hariot 1889 on Metabolic Reactions under Acute Stress
The effect of a lipid extract isolated from the marine green algae Codium fragile (Suringar) Hariot on the liver and blood biochemical indicators in...
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Assessment of activity and heart rate as indicators for acute stress in Atlantic salmon
The aim of this study was to assess whether activity and heart rate sensor implants can be used to measure stress and thus estimate one important...
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Mitigation of Acute Hepatotoxicity Induced by Cadmium Through Morin: Modulation of Oxidative and Pro-apoptotic Endoplasmic Reticulum Stress and Inflammatory Responses in Rats
Cadmium (Cd) is a toxic heavy metal with significant environmental health hazards. It enters the body through various routes with tissue...
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Transcriptomic Response of the Atlantic Surfclam (Spisula solidissima) to Acute Heat Stress
There is clear evidence that the oceans are warming due to anthropogenic climate change, and the northeastern coast of USA contains some of the...
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Scutellarein ameliorates inflammation and oxidative stress in L-arginine induced acute pancreatitis in mice through regulating the expression of VEGF
BackgroundAcute pancreatitis (AP) is an abdominal disease mainly characterized by oxidative stress and inflammation of the pancreas. Studies have...
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Metabolism, antioxidant and immunity in acute and chronic hypoxic stress and the improving effect of vitamin C in the channel catfish (Ictalurus punctatus)
Hypoxia is the most significant factor that threatens the health and even survival of freshwater and marine fish. Priority should be given to the...
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Effect of Acute Hypoxia on Oxidative Stress Indices in Rat Offspring at Different Stages of Gestation
Abstract—Intrauterine hypoxia is the most common prenatal risk factor presenting a direct danger not only to the life of the fetus but also to the...
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Nuclear SPHK2/S1P induces oxidative stress and NLRP3 inflammasome activation via promoting p53 acetylation in lipopolysaccharide-induced acute lung injury
A bulk of evidence identified that macrophages, including resident alveolar macrophages and recruited macrophages from the blood, played an important...
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Acute stress response on Atlantic salmon: a time-course study of the effects on plasma metabolites, mucus cortisol levels, and head kidney transcriptome profile
Farmed Atlantic salmon ( Salmo salar ) welfare and performance can be strongly influenced by stress episodes caused by handling during farming...
