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Mutation of a highly conserved base in the yeast mitochondrial 21S rRNA restricts ribosomal frameshifting
A mutation shown to cause resistance to chloramphenicol in Saccharomyces cerevisiae was mapped to the central loop in domain V of the yeast...
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Incorporation of the yeast mitochondrial ribosomal protein Mrp2 into ribosomal subunits requires the mitochondrially encoded Var1 protein
Mrp2 is a protein component of the small subunit of mitochondrial ribosomes in the yeast Saccharomyces cerevisiae . We have examined the expression of...
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Cloning and analysis of the nuclear gene MRP-S9 encoding mitochondrial ribosomal protein S9 of Saccharomyces cerevisiae
The Saccharomyces cerevisiae nuclear gene MRP-S9 was identified as part of the European effort in sequencing chromosome II. MRP-S9 encodes for a...
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Mitochondrial Genetics of Yeast
Biosynthesis of functional mitochondria is a complex affair, where hundreds of proteins are required to build up the organelle and to keep it...
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Hsp70 in mitochondrial biogenesis: From chaperoning nascent polypeptide chains to facilitation of protein degradation
The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70...
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Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination
Mitochondrial DNA recombination was reduced in an yeast mutant lacking the NUC1 endo/exonuclease. Between linked markers in either the ω or cob ...
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Yeast Mitochondrial Translation: Nuclear Genes Involved in the Expression of the Mitochondrial Genome
A search for nuclear genes involved in mitochondrial translation has been made using genetic suppressors and multicopy suppressors of mitochondrial...
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Translation in Yeast Mitochondria
Mitochondria make a small number of their own proteins. They do this employing a translational apparatus that is clearly unusual (see Benne and...
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Protein folding in the cell: functions of two families of molecular chaperone, hsp 60 and TF55-TCP1
Two families of molecular chaperone, the hsp 60-GroEL family and the TF55-TCP1 family, have been discovered in evolutionarily related cellular...
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Genetic approaches to the study of mitochondrial biogenesis in yeast
In contrast to most other organisms, the yeast Saccharomyces cerevisiae can survive without functional mitochondria. This ability has been exploited...
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Mitochondrial mutations restricting spontaneous translational frameshift suppression in the yeast Saccharomyces cerevisiae
The +1 frameshift mutation, M5631, which is located in the gene ( oxi1 ) for cytochrome c oxidase II (COXII) of the yeast mitochondrial genome, is...
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The yeast mitochondrial leucyl-tRNA synthetase is a splicing factor for the excision of several group I introns
The Saccharomyces cerevisiae nuclear gene NAM2 codes for mitochondrial leucyl-tRNA synthetase (mLRS). Herbert et al. (1988, EMBO J 7:473–483)...
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Antibodies against a fused gene product identify the protein encoded by a group 11 yeast mitochondrial intron
In the mitochondrial genome of Saccharomyces cerevisiae , introns all and aI2 of the gene encoding the COX1 subunit are the only group 11 introns with...
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A single nucleotide substitution at the rib2 locus of the yeast mitochondrial gene for 21S rRNA confers resistance to erythromycin and cold-sensitive ribosome assembly
We have studied a mutation (cs23) in the mitochondrial gene for 21SrRNA that affects the peptidyl transferase center of the ribosome and...
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DNA sequence analysis of the apocytochrome b gene of Podospora anserina: a new family of intronic open reading frame
The 5,969 by (base pair) DNA sequence of the apocytochrome b mitochondrial (mt) gene of race A Podospora anserina was located in a 8.5 Kbp region....
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The paromomycin resistance mutation (par r-454) in the 15 S rRNA gene of the yeastSaccharomyces cerevisiae is involved in ribosomal frameshifting
The leaky expression of the yeast mitochondrial gene oxi1 , containing a frameshift mutation (+1), is caused by natural frameshift suppression, as...
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Nucleo-mitochondrial interactions in yeast mitochondrial biogenesis
For what once were probably free-living aerobic bacteria, mitochondria show a surprising degree of domestication in terms of their dependence on the...