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1. The Role of Mechanosensitive Signaling Cascades in Repair and Fibrotic Remodeling of the Infarcted Heart

   The adult mammalian heart has negligible regenerative capacity and heals through formation of a collagen-based scar. Repair of the infarcted heart...

   Claudio Humeres, Harikrishnan Venugopal, Nikolaos G. Frangogiannis in Cardiac Mechanobiology in Physiology and Disease

   Chapter 2023
   

2. TRPM2 knockdown attenuates myocardial apoptosis and promotes autophagy in HFD/STZ-induced diabetic mice via regulating the MEK/ERK and mTORC1 signaling pathway

   Diabetic cardiomyopathy (DCM) is a major complication of diabetes. Transient receptor potential melastatin 2 (TRPM2) activity increases in diabetic...

   Feng Hu, Chaoyang Lin in Molecular and Cellular Biochemistry

   Article Open access 03 February 2024
   

3. TRP channel expression correlates with the epithelial–mesenchymal transition and high-risk endometrial carcinoma

   Transient receptor potential (TRP) channels excel in cellular sensing as they allow rapid ion influx across the plasma membrane in response to a...

   Charlotte Van den Eynde, Katrien De Clercq, ... Joris Vriens in Cellular and Molecular Life Sciences

   Article Open access 22 December 2021
   

4. The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins

   The melastatin-related transient receptor potential member 7 (TRPM7) is a unique fusion protein with both ion channel function and enzymatic α-kinase...

   Sayuri Suzuki, Annette Lis, ... Andrea Fleig in Cellular and Molecular Life Sciences

   Article 02 March 2018
   

5. Pathophysiological role of calcium channels and transporters in the multiple myeloma

   Multiple myeloma (MM) is a common malignant tumor of plasma cells. Despite several treatment approaches in the past two decades, MM remains an...

   Tingting Li, Junmin Chen, Zhiyong Zeng in Cell Communication and Signaling

   Article Open access 27 September 2021
   

6. RETRACTED ARTICLE: Transient Receptor Potential (TRP) Family of Channel Proteins

   Abstract

   Proteins with a transient receptor potential (TRP) function in the cell membrane as Ca ²⁺ -permeable nonselective cation channels. TRP...

   E. E. Kuvaeva, I. B. Mertsalov, O. B. Simonova in Russian Journal of Developmental Biology

   Article 01 October 2022
   

7. Non-coding RNAs and angiogenesis in cardiovascular diseases: a comprehensive review

   Non-coding RNAs (ncRNAs) have key roles in the etiology of many illnesses, including heart failure, myocardial infarction, stroke, and in...

   Jie Zhang in Molecular and Cellular Biochemistry

   Article 02 February 2024
   

8. TRPM2-mediated Ca²⁺ signaling as a potential therapeutic target in cancer treatment: an updated review of its role in survival and proliferation of cancer cells

   The transient receptor potential melastatin subfamily member 2 (TRPM2), a thermo and reactive oxygen species (ROS) sensitive Ca ²⁺ -permeable cation...

   Eunus S. Ali, Brototi Chakrabarty, ... William C. Cho in Cell Communication and Signaling

   Article Open access 19 June 2023
   

9. Non-coding RNAs regulating endothelial progenitor cells for venous thrombosis: promising therapy and innovation

   Venous thromboembolism, which includes deep venous thrombosis (DVT) and pulmonary embolism, is the third most common vascular disease in the world...

   Li-Li Sun, Zhao Liu, ... Wen-Dong Li in Stem Cell Research & Therapy

   Article Open access 02 January 2024
   

10. Role of store-operated Ca2+ entry in cardiovascular disease

    Store-operated channels (SOCs) are highly selective Ca2+ channels that mediate Ca2+ influx in non-excitable and excitable (i.e., skeletal and cardiac...

    Ting Lu, Yihua Zhang, ... Qiang Xu in Cell Communication and Signaling

    Article Open access 18 March 2022
    

11. The LCK-14-3-3ζ-TRPM8 axis regulates TRPM8 function/assembly and promotes pancreatic cancer malignancy

    Transient receptor potential melastatin 8 (TRPM8) functions as a Ca ²⁺ -permeable channel in the plasma membrane (PM). Dysfunction of TRPM8 is...

    Yuan Huang, Shi Li, ... **gfeng Tang in Cell Death & Disease

    Article Open access 04 June 2022
    

12. Hypoxia and interleukin-1-primed mesenchymal stem/stromal cells as novel therapy for stroke

    Promising preclinical stroke research has not yielded meaningful and significant success in clinical trials. This lack of success has prompted the...

    Maryam Adenike Salaudeen, Stuart Allan, Emmanuel Pinteaux in Human Cell

    Article Open access 21 November 2023
    

13. Disruption of Calcium Homeostasis and Following Changes in Calcium Signaling in Neurons and Glial Cells in Response to Photodynamic Treatment

    Abstract

    Photodynamic impact on neurons and glial cells, causing oxidative stress and ischemic damage, is accompanied by disruption of calcium...

    B. A. Dzreyan, A. M. Khaitin, S. V. Demyanenko in Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology

    Article 15 August 2022
    

14. A Mini Review on the Various Facets Effecting Brain Delivery of Magnesium and Its Role in Neurological Disorders

    Magnesium is an essential cation present in the body that participates in the regulation of various vital body functions. Maintaining normal level of...

    Aparna Ann Mathew, Rajitha Panonnummal in Biological Trace Element Research

    Article 19 December 2022
    

15. Magnesium-enriched microenvironment promotes odontogenic differentiation in human dental pulp stem cells by activating ERK/BMP2/Smads signaling

    Background

    Magnesium (Mg ²⁺ )-enriched microenvironment promotes odontogenic differentiation in human dental pulp stem cells (DPSCs), but the...

    Yuanyuan Kong, **aoli Hu, ... Jianmao Zheng in Stem Cell Research & Therapy

    Article Open access 10 December 2019
    

16. Identification of perturbed pathways rendering susceptibility to tuberculosis in type 2 diabetes mellitus patients using BioNSi simulation of integrated networks of implicated human genes

    In type 2 diabetes mellitus (T2DM) patients, chronic hyperglycemia and inflammation underlie susceptibility to tuberculosis (TB) and result in poor...

    Jyoti Rani, Anasuya Bhargav, ... Srinivasan Ramachandran in Journal of Biosciences

    Article 07 December 2022
    

17. Screening and expression analysis of genes related to skin coloration in pearlscale angelfish (Centropyge vrolikii)

    The skin coloration is one of the key characteristics of fish morphological diversity; understanding the molecular regulation mechanism of fish skin...

    Li-jun He, Zhen Yang, ... Yong-hua Jiang in Aquaculture International

    Article 10 June 2023
    

18. The role of TRPV4 in programmed cell deaths

    Programmed cell death is a major life activity of both normal development and disease. Necroptosis is early recognized as a caspase-independent form...

    Qingjie Ma, Jilin Wu, ... Na Liu in Molecular Biology Reports

    Article 01 February 2024
    

19. Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells

    Differences in shape can be a distinguishing feature between different cell types, but the shape of a cell can also be dynamic. Changes in cell shape...

    Choon Leng So, Mélanie Robitaille, ... Gregory R. Monteith in Communications Biology

    Article Open access 17 April 2024
    

20. The role of miRNAs from mesenchymal stem/stromal cells-derived extracellular vesicles in neurological disorders

    Mesenchymal stem/stromal cells (MSCs) are multipotent cells with immunomodulatory effects that have been attempted as a possible treatment for...

    Morteza Jafarinia, Majid Reza Farrokhi, ... William C. Cho in Human Cell

    Article 19 October 2022