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Stem Cell-Based Regenerative Approaches for the Treatment of Cleft Lip and Palate: A Comprehensive Review
Cleft lip and/or palate (CLP) is a prevalent congenital craniofacial abnormality that can lead to difficulties in eating, speaking, hearing, and...
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Effect of synthetic bone replacement material of different size on shear stress resistance within impacted native and thermodisinfected cancellous bone: an in vitro femoral impaction bone grafting model
Antibiotic carrier particles of variable size might influence mechanic properties within impacted thermodisinfected and native cancellous bone...
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Stem cells and extracellular vesicles to improve preclinical orofacial soft tissue healing
Orofacial soft tissue wounds caused by surgery for congenital defects, trauma, or disease frequently occur leading to complications affecting...
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Distribution of serum uric acid concentration and its association with lipid profiles: a single-center retrospective study in children aged 3 to 12 years with adenoid and tonsillar hypertrophy
BackgroundPresently, there is no consensus regarding the optimal serum uric acid (SUA) concentration for pediatric patients. Adenoid and tonsillar...
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The quality assessment of the University hospital bone bank in Central Serbia: the second audit after fourteen years
We analyzed the prevalence and predisposing factors for the overall rejection rate after retrieval of 267 fresh femoral head allografts over the past...
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Genetic Engineering Reading, Writing and Editing Genes
This essential should serve as an introduction for a contemporary public discussion on genetic engineering. Genetic engineering affects us all in...
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3D Printing for Orthopedic Joint Tissue Engineering
Focal cartilage defects are common and can lead to pain, functional impairment, and progression to osteoarthritis. Since cartilage has limited...
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A rare case of postoperative Metamycoplasma hominis surgical site infection in a patient after bilateral lung transplantation
Following the COVID-19 infection, the sternum dislocation and wound dehiscence resulted in an infection complicating the recovery of an...
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Burch colposuspension for stress urinary incontinence: a 14-year prospective follow-up
We aimed to evaluate the long-term effectiveness and safety of Burch colposuspension (BC) for stress urinary incontinence (SUI). In this prospective...
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Allografts: expanding the surgeon’s armamentarium
In Germany, bone allografts are widely used and their application in clinics has increased over the years. Successful use of allografts depends on...
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Presenting and Treating Bone Infections Using Silver Ion Containing Nano-hydroxyapatite
Although the cleaner surgical environment, antibiotic use, and surgical asepsis-antisepsis have reduced the incidence of infections during surgery,...
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Case Study #4: Lutathera, a Gold Standard for Peptide Receptor Radiopharmaceutical Therapy
Peptide receptor radionuclide therapy (PRRT) is a subgenre of radiopharmaceutical therapy (RPT) that involves the intravenous administration of a...
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CB2 regulates oxidative stress and osteoclastogenesis through NOX1-dependent signaling pathway in titanium particle-induced osteolysis
Periprosthetic osteolysis (PPO) induced by wear particles at the interface between the prosthesis and bone is a crucial issue of periprosthetic bone...
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Combining autologous bone marrow buffy coat and angioconductive bioceramic rod grafting with advanced core decompression improves short-term outcomes in early avascular necrosis of the femoral head: a prospective, randomized, comparative study
BackgroundTreatment of avascular necrosis of the femoral head (ANFH) in young patients remains a clinical challenge. A current controversy is whether...
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Enhancement of the therapeutic efficacy of mesenchymal stem cell-derived exosomes in osteoarthritis
Osteoarthritis (OA), a common joint disorder with articular cartilage degradation as the main pathological change, is the major source of pain and...
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The theoretical adhesion of Staphylococcus aureus and Pseudomonas aeruginosa as nosocomial pathogens on 3D printing filament materials
Microbial infections and nosocomial diseases associated with biomaterial have become a major problem of public health and largely lead to revision...
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Target Organs of Metals Released from Metal-on-Polyethylene Knee and Hip Arthroplasty Implants: Implications for Tissue Metal Profiles
Metals are used in orthopedic implants. The wear of arthroplasty implant can lead to the release of arthroprosthetic metals, both locally and...
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Magnesium Supplementation Affects the Expression of Sirtuin1, Tumor Protein P53 and Endothelial Nitric Oxide Synthase Genes in Patients with Atherosclerosis: A Double-Blind, Randomized, Placebo-Controlled Trial
Magnesium seems to play a role in improving cardiovascular function, but its exact mechanism is unknown. In this study, we hypothesized that...
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Alternating magnetic fields and antibiotics eradicate biofilm on metal in a synergistic fashion
Hundreds of thousands of human implant procedures require surgical revision each year due to infection. Infections are difficult to treat with...
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Current clinical application of sclera and amniotic membrane for ocular tissue bio-replacement
To report the current clinical applications and trends of scleral and amniotic membrane use in ophthalmology. Review of annual reports from the...
