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1. Vesicle and reaction-diffusion hybrid modeling with STEPS

   Vesicles carry out many essential functions within cells through the processes of endocytosis, exocytosis, and passive and active transport. This...

   Iain Hepburn, Jules Lallouette, ... Erik De Schutter in Communications Biology

   Article Open access 15 May 2024
   

2. Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy

   Polphylipoprotein (PLP) is a recently developed nanoparticle with high biocompatibility and tumor selectivity, and which has demonstrated...

   Atsushi Taninaka, Hiromi Kurokawa, ... Hidemi Shigekawa in Communications Biology

   Article Open access 28 November 2023
   

3. Mechanism of D-Cycloserine Inhibition of D-Amino Acid Transaminase from Haliscomenobacter hydrossis

   Abstract

   D-cycloserine inhibits pyridoxal-5′-phosphate (PLP)-dependent enzymes. Inhibition effect depend on organization of the active site and...

   Alina K. Bakunova, Ilya O. Matyuta, ... Ekaterina Yu. Bezsudnova in Biochemistry (Moscow)

   Article 18 May 2023
   

4. The catalytic mechanism of direction-dependent interactions for 2,3-dihydroxybenzoate decarboxylase

   Abstract

   Benzoic acid decarboxylases offer an elegant alternative to CO ₂ fixation by reverse reaction-carboxylation, which is named the...

   Yan Fan, Si** Wu, ... Song Xue in Applied Microbiology and Biotechnology

   Article 18 October 2023
   

5. Using mechanism similarity to understand enzyme evolution

   Enzyme reactions take place in the active site through a series of catalytic steps, which are collectively termed the enzyme mechanism. The catalytic...

   António J. M. Ribeiro, Ioannis G. Riziotis, ... Janet M. Thornton in Biophysical Reviews

   Article Open access 03 December 2022
   

6. SBMLKinetics: a tool for annotation-independent classification of reaction kinetics for SBML models

   Background

   Reaction networks are widely used as mechanistic models in systems biology to reveal principles of biological systems. Reactions are...

   ** Xu in BMC Bioinformatics

   Article Open access 13 June 2023
   

7. Analysis on the Mechanism of Nectarine Fruit-Cracking

   To explore the fruit-cracking mechanism in nectarine, we compared three cracking-susceptible nectarine varieties (‘Huaguang’, ‘Yanguang’, and...

   Jun Yu, Wen**g Qu, ... Mingtao Zhu in Journal of Plant Growth Regulation

   Article 29 September 2023
   

8. Photoprotection by photoinhibitory and PSII-reaction centre quenching controls growth of Ulva rigida (Chlorophyta) and is a pre-requisite for green tide formation

   Main Conclusion

   The combined photoinhibitory and PSII-reaction centre quenching against light stress is an important mechanism that allows the green...

   Ralf Rautenberger, Catriona L. Hurd in Planta

   Article Open access 05 April 2024
   

9. A Potential Association of Zinc Deficiency and Tyrosine Kinase Inhibitor-Induced Hand-Foot Skin Reaction

   Hand-foot skin reaction (HFSR) is a common skin-related adverse event induced by multikinase inhibitors targeting both platelet-derived growth factor...

   Chun-Nan Yeh, Wen-Kuan Huang, ... Chiao-En Wu in Biological Trace Element Research

   Article 09 March 2023
   

10. Transport mechanism of presynaptic high-affinity choline uptake by CHT1

    Choline is a vital nutrient and a precursor for the biosynthesis of essential metabolites, including acetylcholine (ACh), that play a central role in...

    Yunlong Qiu, Yiwei Gao, ... Yan Zhao in Nature Structural & Molecular Biology

    Article 08 April 2024
    

11. Reaction norm for genomic prediction of plant growth: modeling drought stress response in soybean

    Key message

    We proposed models to predict the effects of genomic and environmental factors on daily soybean growth and applied them to soybean growth...

    Yusuke Toda, Goshi Sasaki, ... Hiroyoshi Iwata in Theoretical and Applied Genetics

    Article Open access 09 March 2024
    

12. Structure and transport mechanism of the human calcium pump SPCA1

    Secretory-pathway Ca ²⁺ -ATPases (SPCAs) play critical roles in maintaining Ca ²⁺ homeostasis, but the exact mechanism of SPCAs-mediated Ca ²⁺ transport...

    Mengqi Wu, Cang Wu, ... Zhongmin Liu in Cell Research

    Article Open access 31 May 2023
    

13. Molecular Mechanism of the Circadian Clock

    Nearly all organisms possess a circadian clock, a genetically determined device that generates endogenous oscillations with a period of approximately...

    David Doležel in Insect Chronobiology

    Chapter 2023
    

14. Ferroptosis in cardiovascular diseases: role and mechanism

    In multicellular organisms, regulatory cell death is a crucial aspect of growth and development. Ferroptosis, which was postulated roughly ten years...

    Qi Zhang, Yuhao Luo, ... **g Luo in Cell & Bioscience

    Article Open access 15 December 2023
    

15. Neural Mechanism of Photoperiodism

    In neural mechanisms underlying photoperiodism, photoperiodic information is received by photoreceptors and is processed in the photoperiodic clock...

    Sakiko Shiga in Insect Chronobiology

    Chapter 2023
    

16. The leprosy reaction is associated with salivary anti-Porphyromonas gingivalis IgA antibodies

    The aim of the study was to evaluate the association between salivary anti- Porphyromonas gingivalis IgA antibodies and the leprosy reaction. The...

    Michelle Miranda Lopes Falcão, Johelle Santana Passos-Soares, ... Soraya Castro Trindade in AMB Express

    Article Open access 07 July 2023
    

17. Preparation, characterization, bacteriostatic efficacy, and mechanism of zinc/selenium-loaded sodium humate

    Abstract

    In recent years, metal-based complexes including selenium (Se) and zinc (Zn)-containing compounds have been widely explored for their...

    Yuying Fan, Jie Li, ... Yun Liu in Applied Microbiology and Biotechnology

    Article 31 October 2023
    

18. Insights into the mechanism of SARS-CoV-2 main protease autocatalytic maturation from model precursors

    A critical step for SARS-CoV-2 assembly and maturation involves the autoactivation of the main protease (MPro ^WT ) from precursor polyproteins. Upon...

    Annie Aniana, Nashaat T. Nashed, ... John M. Louis in Communications Biology

    Article Open access 13 November 2023
    

19. Biomolecules Regulating Defense Mechanism in Plants

    There are two types of defense mechanism in plants which are regulated by biomolecules. Physical defense is the corporeal barrier developed in the...

    Vibhakar A. Chowdhary, Jigna G. Tank in Proceedings of the National Academy of Sciences, India Section B: Biological Sciences

    Article 15 October 2022
    

20. Phenolic compounds induce ferroptosis-like death by promoting hydroxyl radical generation in the Fenton reaction

    Phenolic compounds are industrially versatile chemicals, also the most ubiquitous pollutants. Recently, biosynthesis and biodegradation of phenols...

    **nyue Sui, Jichao Wang, ... Guang Zhao in Communications Biology

    Article Open access 17 February 2024