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Association of DRB1*11 and DRB1*12 alleles of the HLA system with the evolution of the Hepatitis B virus infection in Burkina Faso
BackgroundHepatitis B Virus (HBV) infection affect all social strata of humanity and in the absence of any management, this infection has a different...
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The Relationship Between Zinc Deficiency and Hepatocellular Carcinoma Associated with Hepatitis B Liver Cirrhosis: A 10-year Follow-up Study
Our aim is to evaluate the serum zinc levels in Hepatitis B liver cirrhosis patients and clarify the relationship between the serum zinc levels and...
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Deubiquitinase OTUD5 promotes hepatitis B virus replication by removing K48-linked ubiquitination of HBV core/precore and upregulates HNF4ɑ expressions by inhibiting the ERK1/2/mitogen-activated protein kinase pathway
Hepatitis B virus (HBV) infection is a major public health problem worldwide, causing nearly one million deaths annually. OTUD5 is a deubiquitinase...
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Monoclonal Antibody Panel for Hepatitis B Virus Genotype and HBsAg Subtype Identification: Results Obtained for Blood-Serum Samples from Three Regions of Russia
AbstractWe previously developed a technique that uses the anti-HBs monoclonal antibody panel (MAbs) to determine the major variants of hepatitis B...
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Hepatitis B Core Protein Capsids
Non-enveloped Nackednaviridae and enveloped hepadnaviridae both have capsids that are formed by related small proteins which evolved more than 430...
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rt269L-Type hepatitis B virus (HBV) in genotype C infection leads to improved mitochondrial dynamics via the PERK–eIF2α–ATF4 axis in an HBx protein-dependent manner
BackgroundIn our previous report, the rt269I type versus the rt269L type in genotype C2 infection led to poor clinical outcomes and enhanced...
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Core promoter mutation of nucleotides A1762T and G1764A of hepatitis B virus increases core promoter transactivation by hepatocyte nuclear factor 1
Hepatitis B virus (HBV) infection highly increases the risk for liver cirrhosis and hepatocellular carcinoma (HCC). The clinical manifestation of HBV...
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Markers of Viral Hepatitis B in Blood–Plasma Samples of the Indigenous Population of the Far North of Russia. HBV Genotypes and HBsAg Subtypes
Hepatitis B is a major public health problem worldwide. The indigenous population of remote regions with harsh living conditions, such as the Far...
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Blocking neddylation elicits antiviral effect against hepatitis B virus replication
BackgroundHepatitis B Virus (HBV) is the most common cause of chronic liver disease worldwide. The mechanisms that regulate HBV viral replication...
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Anti-hepatitis B activities of Myanmar medicinal plants: a narrative review of current evidence
Hepatitis B is one of the major burdens for health services and is the leading cause of morbidity and mortality from cirrhosis of liver and...
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Determining the absolute configuration of vanitaracin A, an anti-hepatitis B virus agent
Vanitaracin A is an anti-hepatitis B virus (anti-HBV) compound isolated from the culture broth of the fungus Talaromyces sp. Vanitaracin A inhibits...
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Seroprevalence of hepatitis E virus in patients with chronic liver disease
IntroductionThe seroprevalence of hepatitis E virus (HEV) in patients with chronic liver disease (CLD) is little known in Brazil. Studies have...
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Leveraging stem cells to combat hepatitis: a comprehensive review of recent studies
Hepatitis is a significant global public health concern, with viral infections being the most common cause of liver inflammation. Antiviral...
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Hepatitis B virus (HBV) codon adapts well to the gene expression profile of liver cancer: an evolutionary explanation for HBV’s oncogenic role
Due to the evolutionary arms race between hosts and viruses, viruses must adapt to host translation systems to rapidly synthesize viral proteins....
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The roles of different microRNAs in the regulation of cholesterol in viral hepatitis
Cholesterol plays a significant role in stabilizing lipid or membrane rafts, which are specific cellular membrane structures. Cholesterol is involved...
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Optimization of a rapid and sensitive nucleic acid lateral flow biosensor for hepatitis B virus detection
Background and objectiveThe utilization of direct amplification of nucleic acid from lysate has attracted interest in the advancement of...
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PRKDC promotes hepatitis B virus transcription through enhancing the binding of RNA Pol II to cccDNA
Hepatitis B virus infection remains a major health problem worldwide due to its high risk of liver failure and hepatocellular carcinoma. Covalently...
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Low Serum Soluble Transferrin Receptor Levels Are Associated with Poor Prognosis in Patients with Hepatitis B Virus–Related Acute-on-Chronic Liver Failure
Iron metabolism disorder is closely related to acute-on-chronic liver failure (ACLF). This study was conducted to analyze the serum levels of soluble...
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Development of sensitive and specific loop-mediated isothermal amplification combined with lateral flow device for the rapid detection of hepatitis B virus infection
AbstractHepatitis B virus is a highly infectious blood borne microbial pathogen that causes several hepatic complications like liver cirrhosis and...
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Hepatitis B virus particles activate B cells through the TLR2–MyD88–mTOR axis
Host immune control plays a pivotal role in resolving primary hepatitis-B-virus (HBV) infections. The complex interaction between HBV and host immune...
