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Characterizing chromatin interactions of regulatory elements and nucleosome positions, using Hi-C, Micro-C, and promoter capture Micro-C
BackgroundRegulatory elements such as promoters, enhancers, and insulators interact each other to mediate molecular processes. To capture chromatin...
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Long-insert sequence capture detects high copy numbers in a defence-related beta-glucosidase gene βglu-1 with large variations in white spruce but not Norway spruce
Conifers are long-lived and slow-evolving, thus requiring effective defences against their fast-evolving insect natural enemies. The copy number...
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Inadvertent human genomic bycatch and intentional capture raise beneficial applications and ethical concerns with environmental DNA
The field of environmental DNA (eDNA) is advancing rapidly, yet human eDNA applications remain underutilized and underconsidered. Broader adoption of...
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Targeted 16S rRNA Gene Capture by Hybridization and Bioinformatic Analysis
Next-generation sequencing technologies have impressively unlocked capacities to depict the complexity of microbial communitiesMicrobial communities....
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A PPIX-binding probe facilitates discovery of PPIX-induced cell death modulation by peroxiredoxin
While heme synthesis requires the formation of a potentially lethal intermediate, protoporphyrin IX (PPIX), surprisingly little is known about the...
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Resolving the phylogeny of Thladiantha (Cucurbitaceae) with three different target capture pipelines
BackgroundDespite recent advances, reliable tools to simultaneously handle different types of sequencing data (e.g., target capture, genome skimming)...
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Scalable in situ single-cell profiling by electrophoretic capture of mRNA using EEL FISH
Methods to spatially profile the transcriptome are dominated by a trade-off between resolution and throughput. Here we develop a method named...
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Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes
Accurate chromosome segregation during meiosis is crucial for reproduction. Human and porcine oocytes transiently cluster their chromosomes before...
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Capture of regulatory factors via CRISPR–dCas9 for mechanistic analysis of fine-tuned SERRATE expression in Arabidopsis
SERRATE (SE) plays an important role in many biological processes and under biotic stress resistance. However, little about the control of SE has...
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Pump-Probe Spectroscopy, Photon Echoes, Two-Dimensional Spectroscopy and Vibrational Wavepackets
In the last chapter, we used a steady-state treatment to relate the shape of an absorption band to the dynamics of relaxations in the excited state....
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Reinvestigation on primary processes of PSII-dimer from Thermosynechococcus vulcanus by femtosecond pump-probe spectroscopy
Cyanobacterial photosynthetic apparatus efficiently capture sunlight, and the energy is subsequently transferred to photosystem I (PSI) and II...
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Recent advances in chromosome capture techniques unraveling 3D genome architecture in germ cells, health, and disease
In eukaryotes, the genome does not emerge in a specific shape but rather as a hierarchial bundle within the nucleus. This multifaceted genome...
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Multi-probe attention neural network for COVID-19 semantic indexing
BackgroundThe COVID-19 pandemic has increasingly accelerated the publication pace of scientific literature. How to efficiently curate and index this...
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Proton boron capture therapy (PBCT) induces cell death and mitophagy in a heterotopic glioblastoma model
Despite aggressive therapeutic regimens, glioblastoma (GBM) represents a deadly brain tumor with significant aggressiveness, radioresistance and...
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Development of primer–probe sets for environmental DNA-based monitoring of pond smelt Hypomesus nipponensis and Japanese icefish Salangichthys microdon
The pond smelt Hypomesus nipponensis and Japanese icefish Salangichthys microdon are economically important fishery resources in Japan. The catching...
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Methods for Target Enrichment Sequencing via Probe Capture in Legumes
Target enrichment sequencing (TES) is a powerful approach to deep-sequencing the exome or genomic regions of interest with great depth. Although...
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Construction of a strawberry breeding core collection to capture and exploit genetic variation
BackgroundGenetic diversity is crucial for the success of plant breeding programs and core collections are important resources to capture this...
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Current sequence-based models capture gene expression determinants in promoters but mostly ignore distal enhancers
BackgroundThe largest sequence-based models of transcription control to date are obtained by predicting genome-wide gene regulatory assays across the...
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Thioester Capture Strategy for the Identification of Nonribosomal Peptide and Polyketide Intermediates
Nonribosomal peptide synthetases (NRPSs) and polyketide synthases (PKSs) are multi-domainal megasynthases. While they are capable of generating a...
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Chromosome Conformation Capture in Bacteria and Archaea
The three-dimensional structure of the chromosome is encoded within its sequence and regulates activities such as replication and transcription. This...