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Pnpla5-knockout rats exhibit reduced expression levels of proteins involved in steroid metabolism and wound healing compared to wild-type rats
BackgroundPatatin-like phospholipase domain containing 5 (PNPLA5) is a newly-discovered lipase. Although the PNPLA family plays critical roles in...
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Molecular cloning and expression patterns of a sex-biased transcriptional factor Foxl2 in the giant freshwater prawn (Macrobrachium rosenbergii)
BackgroudMacrobrachium rosenbergii is an economically important species that is widely cultivated in some Asian nations. Foxl2 is a transcriptional...
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Sources and control of impurity during one-pot enzymatic production of dehydroepiandrosterone
AbstractDehydroepiandrosterone (DHEA) has a promising market due to its capacity to regulate human hormone levels as well as preventing and treating...
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A Comparative Study of the Steroidogenic Effect of 5-Amino-
N-tert -butyl-2-(methylthio)-4-(3-(nicotinamido)phenyl)thieno[2,3-d ]-pyrimidine-6-carboxamide and Chorionic Gonadotropin with Different Methods of Administration to Male RatsAbstractTo correct androgen deficiency, it is necessary to develop new luteinizing hormone receptor (LHR) agonists and evaluate their steroidogenic...
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The metabolites of Piper sarmentosum and their biological properties: a recent update
Piper sarmentosum (Piperaceae) is a well-recognized traditional medicinal plant and has attracted considerable attention due to its extensive range...
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The Effects of Chronic Lead Exposure on Testicular Development of Japanese Quail (Coturnix japonica): Histopathological Damages, Oxidative Stress, Steroidogenesis Disturbance, and Hypothalamus-Pituitary-Testis Axis Disruption
Lead (Pb) becomes a global public health concern for its high toxicology. Birds are sensitive to environmental pollution and Pb contamination exerts...
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Identifying the genes involved in the egg-carrying ovigerous hair development of the female blue crab Callinectes sapidus: transcriptomic and genomic expression analyses
BackgroundCrustacean female sex hormone (CFSH) controls gradually develo** adult female-specific morphological features essential for mating and...
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Reproduction-associated pathways in females of gibel carp (Carassius gibelio) shed light on the molecular mechanisms of the coexistence of asexual and sexual reproduction
Gibel carp ( Carassius gibelio ) is a cyprinid fish that originated in eastern Eurasia and is considered as invasive in European freshwater ecosystems....
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Role of the AMP-Activated Protein Kinase in the Pathogenesis of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a complex disorder characterized by elevated androgen levels, menstrual irregularities, and polycystic morphology...
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Enhanced resistance to heat and fungal infection in transgenic Trichoderma via over-expressing the HSP70 gene
Heat stress is one of the major abiotic stresses affecting the growth, sporulation, colonization and survival of Trichoderma viride . This study aimed...
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Association of polymorphisms of HSD11B1 and ACE genes with trachoma disease
Trachoma, caused by Chlamydia trachomatis , is the most common infectious blindness in the world and is present in indigenous Mayan from Chiapas...
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Identification and Characterization of Some Genes, Enzymes, and Metabolic Intermediates Belonging to the Bile Acid Aerobic Catabolic Pathway from Pseudomonas
The study of the catabolic potential of microbial species isolated from different habitats has allowed the identification and characterization of...
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The bacterial metabolite, lithocholic acid, has antineoplastic effects in pancreatic adenocarcinoma
Lithocholic acid (LCA) is a secondary bile acid. LCA enters the circulation after bacterial synthesis in the gastrointestinal tract, reaches...
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Adeno-associated virus-based caveolin-1 delivery via different routes for the prevention of cholesterol gallstone formation
BackgroundHepatic caveolin-1 (CAV1) is reduced in cholesterol gallstone disease (CGD). Mice with CAV1 deficiency were prone to develop CGD. However,...
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Non-classical animal models for studying adrenal diseases: advantages, limitations, and implications for research
The study of adrenal disorders is a key component of scientific research, driven by the complex innervation, unique structure, and essential...
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Bioconversion of Phytosterols into Androstenedione by Mycolicibacterium
The chapter describes the bioconversion of phytosterols into androstenedione (AD) by Mycolicibacterium spp. in shake flasks and fermenters, as well...
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Elevated luteinizing hormone receptor signaling or selenium treatment leads to comparable changes in adrenal cortex histology and androgen-AR/ZIP9 signaling
The importance and regulation of adrenal androgen production and signaling are not completely understood and are scarcely studied. In addition, there...
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Phytoestrogens as Endocrine-Disrupting Agents in Aquaculture
Phytoestrogens are estrogen-mimicking chemicals produced by terrestrial plants. Thus, they are an integral part of plant-based feed ingredients used...
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Fomitopsis betulina (Bull.) B.K. Cui, M.L. Han & Y.C. Dai; Fomitopsis pinicola (Sw.) P. Karst. - FOMITOPSIDACEAE
Fomitopsis betulina (Bull.) B.K. Cui, M.L. Han & Y.C. Dai; Fomitopsis pinicola (Sw.) P. Karst. - FOMITOPSIDACEAE
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A Novel Method to Differentiate Tonsil-Derived Mesenchymal Stem Cells In Vitro into Estrogen-Secreting Cells
BACKGROUND:The advantages of tonsil-derived mesenchymal stem cells (TMSCs) over other mesenchymal stem cells (MSCs) include higher proliferation...
