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Showing 321-333 of 333 results

  1. Dissecting microregulation of a master regulatory network

    Background

    The master regulator p53 tumor-suppressor protein through coordination of several downstream target genes and upstream transcription...

    Amit U Sinha, Vivek Kaimal, ... Anil G Jegga in BMC Genomics
    Article Open access 23 February 2008

  2. PIM1 and MYC: a changing relationship?

    Jean-Francois Naud, Martin Eilers in Nature Cell Biology
    Article 01 August 2007

  3. Cartilage-selective genes identified in genome-scale analysis of non-cartilage and cartilage gene expression

    Background

    Cartilage plays a fundamental role in the development of the human skeleton. Early in embryogenesis, mesenchymal cells condense and...

    Vincent A Funari, Allen Day, ... Daniel H Cohn in BMC Genomics
    Article Open access 12 June 2007

  4. Genome-wide changes accompanying knockdown of fatty acid synthase in breast cancer

    Background

    The lipogenic enzyme fatty acid synthase (FAS) is up-regulated in a wide variety of cancers, and is considered a potential metabolic...

    Lynn M Knowles, Jeffrey W Smith in BMC Genomics
    Article Open access 12 June 2007

  5. Mining expressed sequence tags identifies cancer markers of clinical interest

    Background

    Gene expression data are a rich source of information about the transcriptional dis-regulation of genes in cancer. Genes that display...

    Fabien Campagne, Lucy Skrabanek in BMC Bioinformatics
    Article Open access 01 November 2006

  6. Transcription Factor Centric Discovery of Regulatory Elements in Mammalian Genomes Using Alignment-Independent Conservation Maps

    The computational identification of DNA binding sites that have high affinity for a specific transcription factor is an important problem that has...
    Nilanjana Banerjee, Andrea Califano in Comparative Genomics
    Conference paper 2006

  7. A Profile HMM for Recognition of Hormone Response Elements

    Steroid hormones are necessary for most vital functions of vertebrate organisms, and act within cells via interaction with their receptor molecules....
    Maria Stepanova, Feng Lin, Valerie C. -L. Lin in Pattern Recognition in Bioinformatics
    Conference paper 2006

  8. Gene Expression Signatures of TGF-β/Smad-Induced Responses

    Microarray technology has enabled large-scale discovery of transcriptional targets of important signaling pathways, including signal transducers of...
    Erwin P. Böttinger, Wenjun Ju in Smad Signal Transduction
    Chapter 2006

  9. Wound healing and inflammation genes revealed by array analysis of 'macrophageless' PU.1 null mice

    Background

    Wound healing is a complex process requiring the collaborative efforts of different tissues and cell lineages, and involving the...

    Lisa Cooper, Claire Johnson, ... Paul Martin in Genome Biology
    Article Open access 23 December 2004

  10. Suggestive Linkage of 2p22-25 and 11q12-13 with Low Bone Mineral Density at the Lumbar Spine in the Irish Population

    Osteoporosis is a disease characterized by low bone mineral density (BMD) and poor bone quality. Peak bone density is achieved by the third decade of...

    F. Wynne, F. J. Drummond, ... K. A. Quane in Calcified Tissue International
    Article 03 April 2003

  12. The gene encoding the Fos-related antigen 2 (Fosl2) maps to mouse chromosome 5

    C. Poirier, A. Lalouette, ... Jean-Louis Guénet in Mammalian Genome
    Article 01 March 1997

  13. The trefoil gene maps to mouse chromosome 17

    M. Burmeister, G. E. Meyer in Mammalian Genome
    Article 01 March 1997
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