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  1. Evolutionary shift detection with ensemble variable selection

    Abrupt environmental changes can lead to evolutionary shifts in trait evolution. Identifying these shifts is an important step in understanding the...

    Wensha Zhang, Toby Kenney, Lam Si Tung Ho in BMC Ecology and Evolution
    Article Open access 20 January 2024
  2. Robust variable selection with exponential squared loss for the partially linear varying coefficient spatial autoregressive model

    The partially linear varying coefficient spatial autoregressive model is a semi-parametric spatial autoregressive model in which the coefficients of...

    Jialei Yu, Yunquan Song, Jiang Du in Environmental and Ecological Statistics
    Article 13 February 2024
  3. BGWAS: Bayesian variable selection in linear mixed models with nonlocal priors for genome-wide association studies

    Background

    Genome-wide association studies (GWAS) seek to identify single nucleotide polymorphisms (SNPs) that cause observed phenotypes. However,...

    Jacob Williams, Shuangshuang Xu, Marco A. R. Ferreira in BMC Bioinformatics
    Article Open access 11 May 2023
  4. Grace-AKO: a novel and stable knockoff filter for variable selection incorporating gene network structures

    Motivation

    Variable selection is a common statistical approach to identifying genes associated with clinical outcomes of scientific interest. There...

    Peixin Tian, Yiqian Hu, ... Yan Dora Zhang in BMC Bioinformatics
    Article Open access 14 November 2022
  5. BG2: Bayesian variable selection in generalized linear mixed models with nonlocal priors for non-Gaussian GWAS data

    Background

    Genome-wide association studies (GWASes) aim to identify single nucleotide polymorphisms (SNPs) associated with a given phenotype. A common...

    Shuangshuang Xu, Jacob Williams, Marco A. R. Ferreira in BMC Bioinformatics
    Article Open access 15 September 2023
  6. Combining heterogeneous subgroups with graph-structured variable selection priors for Cox regression

    Background

    Important objectives in cancer research are the prediction of a patient’s risk based on molecular measurements such as gene expression data...

    Katrin Madjar, Manuela Zucknick, ... Jörg Rahnenführer in BMC Bioinformatics
    Article Open access 11 December 2021
  7. Randomized boosting with multivariable base-learners for high-dimensional variable selection and prediction

    Background

    Statistical boosting is a computational approach to select and estimate interpretable prediction models for high-dimensional biomedical...

    Christian Staerk, Andreas Mayr in BMC Bioinformatics
    Article Open access 16 September 2021
  8. Analysis of polygenic selection in purebred and crossbred pig genomes using generation proxy selection map**

    Background

    Artificial selection on quantitative traits using breeding values and selection indices in commercial livestock breeding populations causes...

    Caleb J. Grohmann, Caleb M. Shull, ... Jared E. Decker in Genetics Selection Evolution
    Article Open access 14 September 2023
  9. Directional selection coupled with kin selection favors the establishment of senescence

    Background

    Conventional wisdom in evolutionary theory considers aging as a non-selected byproduct of natural selection. Based on this, conviction...

    András Szilágyi, Tamás Czárán, ... Eörs Szathmáry in BMC Biology
    Article Open access 23 October 2023
  10. Selection signatures and population dynamics of transposable elements in lima bean

    The domestication process in lima bean ( Phaseolus lunatus L.) involves two independent events, within the Mesoamerican and Andean gene pools. This...

    Daniela Lozano-Arce, Tatiana García, ... Jorge Duitama in Communications Biology
    Article Open access 02 August 2023
  11. Scale-dependent habitat selection is shaped by landscape context in dispersing white-tailed deer

    Context

    Identifying how animals select habitat while navigating landscapes is important for understanding behavioral ecology and guiding management...

    Ryan B. Stephens, Joshua J. Millspaugh, ... Remington J. Moll in Landscape Ecology
    Article Open access 30 March 2024
  12. Selection index theory for populations under directional and stabilizing selection

    Background

    The purpose of a selection index is that its use to select animals for breeding maximizes the profit of a breed in future generations. The...

    Robin Wellmann in Genetics Selection Evolution
    Article Open access 03 February 2023
  13. Evaluating spatially variable gene detection methods for spatial transcriptomics data

    Background

    The identification of genes that vary across spatial domains in tissues and cells is an essential step for spatial transcriptomics data...

    Carissa Chen, Hani Jieun Kim, Pengyi Yang in Genome Biology
    Article Open access 15 January 2024
  14. Bayesian variable selection for high-dimensional data with an ordinal response: identifying genes associated with prognostic risk group in acute myeloid leukemia

    Background

    Acute myeloid leukemia (AML) is a heterogeneous cancer of the blood, though specific recurring cytogenetic abnormalities in AML are...

    Yiran Zhang, Kellie J. Archer in BMC Bioinformatics
    Article Open access 02 November 2021
  15. Food patch selection by the largest European herbivore

    The scaling relationship between digestive system and body mass shapes foraging strategies in herbivores. The Jarman–Bell principle and the forage...

    Rafał Kowalczyk, Tomasz Kamiński, Tomasz Borowik in Mammalian Biology
    Article Open access 04 June 2024
  16. Landscape context and behavioral clustering contribute to flexible habitat selection strategies in a large mammal

    An understanding of individual variation in animal habitat selection is important for effective conservation and management as well as predicting...

    Nathan D. Hooven, Kathleen E. Williams, ... John J. Cox in Mammal Research
    Article 03 June 2024
  17. Variable Selection for Time-to-Event Data

    With the increasing availability of large scale biomedical and -omics data, researchers are offered with unprecedented opportunities to discover...
    Protocol 2021
  18. A Framework for Selection of High-Yielding and Drought-tolerant Genotypes of Barley: Applying Yield-Based Indices and Multi-index Selection Models

    Drought stress is one of the major environmental stresses that dramatically reduces agricultural production around the world. Barley ( Hordeum vulgare ...

    Habibollah Ghazvini, Alireza Pour-Aboughadareh, ... Jan Bocianowski in Journal of Crop Health
    Article 25 April 2024
  19. MarkerMap: nonlinear marker selection for single-cell studies

    Single-cell RNA-seq data allow the quantification of cell type differences across a growing set of biological contexts. However, pinpointing a small...

    Wilson Gregory, Nabeel Sarwar, ... Bianca Dumitrascu in npj Systems Biology and Applications
    Article Open access 14 February 2024
  20. Comparison of cancer subtype identification methods combined with feature selection methods in omics data analysis

    Background

    Cancer subtype identification is important for the early diagnosis of cancer and the provision of adequate treatment. Prior to identifying...

    JiYoon Park, Jae Won Lee, Mira Park in BioData Mining
    Article Open access 07 July 2023
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