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The different subtelomeric structure among 1RS arms in wheat-rye 1BL.1RS translocations affecting their meiotic recombination and inducing their structural variation
BackgroundThe 1RS arm of wheat-rye 1BL.1RS translocations contains several subtelomeric tandem repeat families. To study the effect of the difference...
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Meiotic Recombination
The main outcome of this chapter is to extend the forward simulation program FORTUNA to include crossing-over within a simulated sequence. We begin...
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Meiotic recombination dynamics in plants with repeat-based holocentromeres shed light on the primary drivers of crossover patterning
Centromeres strongly affect (epi)genomic architecture and meiotic recombination dynamics, influencing the overall distribution and frequency of...
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ZmSPO11-2 is critical for meiotic recombination in maize
Most plant species have three or more SPO11/TOPOVIA homologs and two TOPOVIB homologs, which associate to trigger meiotic double-strand break (DSB)...
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Effects of epistasis and recombination between vaccine-escape and virulence alleles on the dynamics of pathogen adaptation
Pathogen adaptation to public health interventions such as vaccination may take tortuous routes and involve multiple mutations at different locations...
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Evolution of the recombination regulator PRDM9 in minke whales
BackgroundPRDM9 is a key regulator of meiotic recombination in most metazoans, responsible for reshuffling parental genomes. During meiosis, the...
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Spontaneous cell fusions as a mechanism of parasexual recombination in tumour cell populations
The initiation and progression of cancers reflect the underlying process of somatic evolution, in which the diversification of heritable phenotypes...
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The structure-specific endonuclease complex SLX4–XPF regulates Tus–Ter-induced homologous recombination
Vertebrate replication forks arrested at interstrand DNA cross-links (ICLs) engage the Fanconi anemia pathway to incise arrested forks, ‘unhooking’...
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Connected pretopology in recombination space
Topological features evolved from genetic operators in the recombination space play a crucial role in the course of evolution. Different crossover...
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Fludarabine increases nuclease-free AAV- and CRISPR/Cas9-mediated homologous recombination in mice
Homologous recombination (HR)-based gene therapy using adeno-associated viruses (AAV-HR) without nucleases has several advantages over classic gene...
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Symmetric subgenomes and balanced homoeolog expression stabilize the establishment of allopolyploidy in cyprinid fish
BackgroundInterspecific postzygotic reproduction isolation results from large genetic divergence between the subgenomes of established hybrids....
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Assembly of the complete mitochondrial genome of an endemic plant, Scutellaria tsinyunensis, revealed the existence of two conformations generated by a repeat-mediated recombination
Main conclusionWe assembled the complete mitochondrial genome of Scutellaria tsinyunensis in this study. Repeat-mediated recombination resulted in...
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Non-Mendelian Genetics: Finding of Transposable Elements in Corns and Flies
The essence of Mendelian genetics is the rule of chromosome segregation and the independent assortment of different chromosomes. However, genes on...
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Drosophila ananassae: a species characterized by spontaneous male recombination in appreciable frequency
Mutation and recombination are primarily responsible for generating the genetic variability in natural populations of microorganisms, plant and...
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Saccharomyces cerevisiae rDNA as super-hub: the region where replication, transcription and recombination meet
Saccharomyces cerevisiae ribosomal DNA, the repeated region where rRNAs are synthesized by about 150 encoding units, hosts all the protein...
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Fine-map** and evolutionary history of R-BPMV, a dominant resistance gene to Bean pod mottle virus in Phaseolus vulgaris L.
Key messageR-BPMV is located within a recently expanded TNL cluster in the Phaseolus genus with suppressed recombination and known for resistance to...
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Timing of appearance of new mutations during yeast meiosis and their association with recombination
Mutations in budding yeast occur in meiosis at higher frequencies than in cells grown vegetatively. In contrast to mutations that occur in somatic...
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Unequal contribution of two paralogous CENH3 variants in cowpea centromere function
In most diploids the centromere-specific histone H3 (CENH3), the assembly site of active centromeres, is encoded by a single copy gene. Persistance...
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High-Density Linkage Map Constructed from a Skim Sequenced Diploid Potato Population Reveals Transmission Distortion and QTLs for Tuber Yield and Pollen Shed
The reinvention of potato, from a tetraploid clonal crop into a diploid seed-based hybrid crop, requires insight in the mutational load,...
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Chromosomal inversion polymorphisms shape the genomic landscape of deer mice
Chromosomal inversions are an important form of structural variation that can affect recombination, chromosome structure and fitness. However,...
