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Hybrid origin and hybrid status of the endangered Ilex sanqingshanensis revealed by molecular and morphological evidence
Identification of natural hybrids considered as endangered species is of vital importance in taxonomy and biodiversity conservation, as natural...
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Molecular and morphological evidences for the hybrid origin of Kushui Rose
Natural hybridization has played a significant role in the evolution of the genus Rosa . Kushui Rose ( R. sertata × R. rugosa ) is a natural hybrid of R....
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Inferring circadian gene regulatory relationships from gene expression data with a hybrid framework
BackgroundThe central biological clock governs numerous facets of mammalian physiology, including sleep, metabolism, and immune system regulation....
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Cotton heterosis and hybrid cultivar development
Cotton, the most important economic crop in the world, displays strong hybrid vigor, and has long been a subject for hybrid cultivar breeding. Here,...
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An early origin of iron–sulfur cluster biosynthesis machineries before Earth oxygenation
Iron–sulfur (Fe–S) clusters are ubiquitous cofactors essential for life. It is largely thought that the emergence of oxygenic photosynthesis and...
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Hybrid Seed Production Technology
Hybrid technology, harnessing the advantage of heterosis between two diverse genotypes to achieve maximum hybrid vigour, is widely recognized and... -
Are there hybrid zones in Fagus sylvatica L. sensu lato?
The complex of beech taxa in western Eurasia ( Fagus sylvatica L. s.l. ) represents one of the most widespread broad-leaved trees in the temperate...
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Structural and biochemical investigations of a HEAT-repeat protein involved in the cytosolic iron-sulfur cluster assembly pathway
Iron-sulfur clusters are essential for life and defects in their biosynthesis lead to human diseases. The mechanism of cluster assembly and delivery...
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Precise in vivo RNA base editing with a wobble-enhanced circular CLUSTER guide RNA
Recruiting the endogenous editing enzyme adenosine deaminase acting on RNA (ADAR) with tailored guide RNAs for adenosine-to-inosine (A-to-I) RNA base...
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A novel hybrid model to predict concomitant diseases for Hashimoto’s thyroiditis
Hashimoto’s thyroiditis is an autoimmune disorder characterized by the destruction of thyroid cells through immune-mediated mechanisms involving...
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Characterisation of the Paenarthrobacter nicotinovorans ATCC 49919 genome and identification of several strains harbouring a highly syntenic nic-genes cluster
BackgroundPaenarthrobacter nicotinovorans ATCC 49919 uses the pyridine-pathway to degrade nicotine and could provide a renewable source of...
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Regional testing of triploid hybrid clones of populus tomentosa
BackgroundTriploid Populus tomentosa , a timber tree species, has been widely planted in northern China owing to its potential high yields and high...
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HycDemux: a hybrid unsupervised approach for accurate barcoded sample demultiplexing in nanopore sequencing
DNA barcodes enable Oxford Nanopore sequencing to sequence multiple barcoded DNA samples on a single flow cell. DNA sequences with the same barcode...
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MLL3 loss drives metastasis by promoting a hybrid epithelial–mesenchymal transition state
Phenotypic plasticity associated with the hybrid epithelial–mesenchymal transition (EMT) is crucial to metastatic seeding and outgrowth. However, the...
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Assessing genetic, racial, and geographic diversity among Ethiopian sorghum landraces and implications for heterotic potential for hybrid sorghum breeding
The wealth of sorghum genetic resources in Africa has not been fully exploited for cultivar development in the continent. Hybrid cultivars developed...
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Transcriptional regulation and overexpression of GST cluster enhances pesticide resistance in the cotton bollworm, Helicoverpa armigera (Lepidoptera: Noctuidae)
The rapid evolution of resistance in agricultural pest poses a serious threat to global food security. However, the mechanisms of resistance through...
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Enzyme-substrate hybrid β-sheet controls geometry and water access to the γ-secretase active site
γ-Secretase is an aspartyl intramembrane protease that cleaves the amyloid precursor protein (APP) involved in Alzheimer’s disease pathology and...
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Site-specific zone delineation for varying Maize Hybrids based on field variability: a multi-hybrid planting application case study in eastern Nebraska
The ability to plant two or more hybrids during a single planting operation (i.e., multi-hybrid planting) has the potential to mitigate in-field...
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Targeted integration in CHO cells using CRIS-PITCh/Bxb1 recombinase–mediated cassette exchange hybrid system
AbstractRecombinant Chinese hamster ovary (CHO) cell line development for complex biotherapeutic production is conventionally based on the random...
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Simulation-based establishment of base pools for a hybrid breeding program in winter rapeseed
Key messageSimulation planned pre-breeding can increase the efficiency of starting a hybrid breeding program.
AbstractStarting a hybrid breeding...