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Functions of Fluoride in the Oral Cavity
Fluoride is an inorganic anion, designated F-, as a halogen element with atomic number 9. It is the simplest anion, similar to hydroxyl ions in...
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Fluoride transport in Arabidopsis thaliana plants is impaired in Fluoride EXporter (FEX) mutants
Fluoride is an environmental toxin prevalent in water, soil, and air. A fluoride transporter called Fluoride EXporter (FEX) has been discovered...
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Effects of Fluoride Toxicity on Female Reproductive System of Mammals: A Meta-Analysis
Considerable integrative efforts have been made to investigate the effects of fluoride on female reproductive organs since the last years. The...
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Fluoride-Induced Mitochondrial Dysfunction and Approaches for Its Intervention
Fluoride is present everywhere in nature. The primary way that individuals are exposed to fluoride is by drinking water. It’s interesting to note...
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Fluoride Induces Neurocytotoxicity by Disrupting Lysosomal Iron Metabolism and Membrane Permeability
The detrimental effects of fluoride on neurotoxicity have been widely recorded, yet the detailed mechanisms underlying these effects remain unclear....
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Metabolomics reveals high fructose-1,6-bisphosphate from fluoride-resistant Streptococcus mutans
BackgroundFluoride-resistant Streptococcus mutans ( S. mutans ) strains have developed due to the wide use of fluoride in dental caries prevention....
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Impact of Fluoride Exposure on Rat Placenta: Foetal/Placental Morphometric Alterations and Decreased Placental Vascular Density
Inorganic fluoride is a geogenic and anthropogenic contaminant widely distributed in the environment and commonly identified in contaminated...
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TGF-β1/Smad3 Signaling Is Required to Alleviate Fluoride-Induced Enamel Hypomineralization
Excessive fluoride intake during enamel development can affect enamel mineralization, leading to dental fluorosis. However, its potential mechanisms...
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Effect of Excess Fluoride Exposure on Radiographic and Histopathological Changes in Long Bones of Rabbit
The present study aimed to investigate the effects of excess fluoride exposure on long bones in young rabbits ( Oryctolagus cuniculus ). New Zealand...
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Soft Drinks as a Dietary Source of Fluoride Exposure
High fluoride exposures can lead to adverse effects such as dental and bone fluorosis, as well as endocrine and cognitive developmental problems....
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Chronic Fluoride Exposure Induces Ovarian Dysfunction and Potential Association with Premature Ovarian Failure in Female Rats
Chronic fluorosis has been widely investigated for its adverse effects on skeletal and neurological health; however, its impact on reproductive...
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Na+/K+ carrier ionophore antibiotics valinomycin and monensin enhance the antibacterial activity of fluoride
Fluoride is routinely used as a highly effective antibacterial agent that interferes with bacterial metabolism through fundamentally different...
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Exercise Alleviates Fluoride-Induced Learning and Memory Impairment in Mice: Role of miR-206-3p and PREG
Fluorosis decreases the learning and memory ability in humans and animals, while exercise can reduce the risk of cognitive decline. However, the...
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ERS Mediated by GRP-78/PERK/CHOP Signaling Is Involved in Fluoride-Induced Ameloblast Apoptosis
Fluoride can be widely ingested from the environment, and its excessive intake could result in adverse effects. Dental fluorosis is an early sign of...
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Fluoride Toxicity Imposes Differential Reprogramming of the Representative Intermediates and Enzymes Belonging to Nitrogen Metabolism in Two indica Rice Varieties, Varying in their Pattern of Fluoride Stress Response
The main aim of this manuscript was to demonstrate the reprogramming of nitrogen and GABA metabolism in the two rice cultivars (Khitish and MTU1010)...
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Proteomics Sequencing Reveals the Role of TGF-β Signaling Pathway in the Peripheral Blood of Offspring Rats Exposed to Fluoride
The underlying mechanism of fluorosis has not been fully elucidated. The purpose of this study was to explore the mechanism of fluorosis induced by...
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Decreased Arsenic Disposition and Alteration of its Metabolic Profile in mice Coexposed to Fluoride
Inorganic arsenic (iAs) and fluoride (iF) are ubiquitous elements whose coexistence is frequent in several regions of the world due to the natural...
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Effects of Treadmill Exercise on Liver Apoptosis in Fluoride-Exposed Mice
Hepatotoxicity induced by excessive fluoride (F) exposure has been extensively studied in both humans and animals. Chronic fluorosis can resul
t in...
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Health Risk Assessment in Mexican Children Exposed to Fluoride from Sweetened Beverages
The primary source of fluoride exposure is groundwater, but evidence suggests that beverages and food are additional fluoride sources. Intake of...
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Combined Effects of Fluoride and Dietary Seleno-L-Methionine at Environmentally Relevant Concentrations on Female Zebrafish (Danio rerio) Liver: Histopathological Damages, Oxidative Stress and Inflammation
Fluoride, a global environmental pollutant, is ubiquitous in aquatic environments and coexists with selenium, which can cause complex effects on...
