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Biogenesis of specialized lysosomes in differentiated keratinocytes relies on close apposition with the Golgi apparatus
Intracellular organelles support cellular physiology in diverse conditions. In the skin, epidermal keratinocytes undergo differentiation with gradual...
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Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic acid cycle and subsequent loss of iron-sulfur cluster...
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Correlation between bioluminescent blinks and swimming behavior in the splitfin flashlight fish Anomalops katoptron
BackgroundThe light organs of the splitfin flashlight fish Anomalops katoptron are necessary for schooling behavior, to determine nearest neighbor...
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Differences in spatiotemporal brain network dynamics of Montessori and traditionally schooled students
Across development, experience has a strong impact on the way we think and adapt. School experience affects academic and social-emotional outcomes,...
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Identification of consensus homozygous regions and their associations with growth and feed efficiency traits in American mink
The recent chromosome-based genome assembly and the newly developed 70K single nucleotide polymorphism (SNP) array for American mink ( Neogale vison )...
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Transcriptome and metabolome analyses reveal regulatory networks associated with nutrition synthesis in sorghum seeds
Cereal seeds are vital for food, feed, and agricultural sustainability because they store and provide essential nutrients to human and animal food...
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Composite branched and linear F-actin maximize myosin-induced membrane shape changes in a biomimetic cell model
The architecture of the actin cortex determines the generation and transmission of stresses, during key events from cell division to migration....
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Goat weed (Ageratum conyzoides L.): A biological threat to plant diversity in Eastern Ghats of India
The Kunming–Montreal Global Biodiversity Framework (GBF) is a recently signed protocol by the conference of the parties (COP 15) with an aim to...
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Joint impact of polygenic risk score and lifestyles on early- and late-onset cardiovascular diseases
Understanding the interactions between genetic risk and lifestyles on different types and age onsets of cardiovascular disease (CVD) risk can help...
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Effect of glyphosate on the sporulation of aquatic fungi: an in-vitro experience
Glyphosate, a herbicide widely used in agriculture, has adverse effects on aquatic ecosystems. This study aimed to assess the repercussions of...
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AtSNU13 modulates pre-mRNA splicing of RBOHD and ALD1 to regulate plant immunity
Pre-mRNA splicing is a significant step for post-transcriptional modifications and functions in a wide range of physiological processes in plants....
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Varroa destructor mite population dynamics in africanized honeybee (Apis mellifera) colonies in a semi-arid region
Most published data on mite infestation rates in semi-arid regions have been collected over only 3 or 4 months during a specific period of the year....
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COQ7 splice site variant causing a spastic paraparesis phenotype in siblings
The COQ7 gene is one of the causative genes for primary COQ10 deficiency-related disorders. OMIM-related phenotypes include severe...
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Investigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization
It is unclear whether poverty and mental illness are causally related. Using UK Biobank and Psychiatric Genomic Consortium data, we examined evidence...
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LRIG1 controls proliferation of adult neural stem cells by facilitating TGFβ and BMP signalling pathways
Adult Neural Stem Cells (aNSCs) in the ventricular-subventricular zone (V-SVZ) are largely quiescent. Here, we characterize the mechanism underlying...
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Methylglyoxal detoxification pathway in barley genotypes after infection with Bipolaris sorokiniana
The present investigation was carried out to study the leaf composition and methylglyoxal pathway in four barley genotypes on infection with Bipolaris...
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Bisphenol S causes excessive estrogen synthesis by activating FSHR and the downstream cAMP/PKA signaling pathway
Estrogen excess in females has been linked to a diverse array of chronic and acute diseases. Emerging research shows that exposure to estrogen-like...
