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Identification of volatile metabolites produced from levodopa metabolism by different bacteria strains of the gut microbiome
Interspecies pathways in the gut microbiome have been shown to metabolize levodopa, the primary treatment for Parkinson’s disease, and reduce its...
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Biochemical characterisation and production kinetics of high molecular-weight (HMW) putative antibacterial proteins of insect pathogenic Brevibacillus laterosporus isolates
BackgroundBacterial genomes often encode structures similar to phage capsids (encapsulins) and phage tails which can be induced spontaneously or...
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An altered uterine microbiota with endometrial hyperplasia
BackgroundEndometrial hyperplasia (EH) is a precursor to endometrial cancer, and the role of the microbiome in its development is unclear.
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Thiolated chitosan nanoparticles encapsulated nisin and selenium: antimicrobial/antibiofilm/anti-attachment/immunomodulatory multi-functional agent
BackgroundThe increase in the resistance of bacterial strains to antibiotics has led to research into the bactericidal potential of non-antibiotic...
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Keypoint-MoSeq: parsing behavior by linking point tracking to pose dynamics
Keypoint tracking algorithms can flexibly quantify animal movement from videos obtained in a wide variety of settings. However, it remains unclear...
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Deep 3D histology powered by tissue clearing, omics and AI
To comprehensively understand tissue and organism physiology and pathophysiology, it is essential to create complete three-dimensional (3D) cellular...
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A roadmap for ribosome assembly in human mitochondria
Mitochondria contain dedicated ribosomes (mitoribosomes), which synthesize the mitochondrial-encoded core components of the oxidative phosphorylation...
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Pathogenomics analysis of high-risk clone ST147 multidrug-resistant Klebsiella pneumoniae isolated from a patient in Egypt
BackgroundThe emergence of multi-drug-resistant Klebsiella pneumoniae (MDR-KP) represents a serious clinical health concern. Antibiotic resistance...
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Resolving chaperone-assisted protein folding on the ribosome at the peptide level
Protein folding in vivo begins during synthesis on the ribosome and is modulated by molecular chaperones that engage the nascent polypeptide. How...
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Green synthesis of zinc oxide nanoparticles (ZnO-NPs) by Streptomyces baarnensis and its active metabolite (Ka): a promising combination against multidrug-resistant ESKAPE pathogens and cytotoxicity
Various eco-friendly techniques are being researched for synthesizing ZnO-NPs, known for their bioactivity. This study aimed at biosynthesizing...
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Evaluating the probiotic effects of spraying lactiplantibacillus plantarum P-8 in neonatal piglets
BackgroundGut microbes play an important role in the growth and health of neonatal piglets. Probiotics can promote the healthy growth of neonatal...
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From a focal skin issue to a systemic disease: the multifaceted nature of cold sores, novel findings
Cold sores, a viral infection caused by the herpes simplex virus, are a prevalent affliction affecting millions of people across the globe. In this...
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Biocontrol potential and growth-promoting effect of endophytic fungus Talaromyces muroii SD1-4 against potato leaf spot disease caused by Alternaria alternata
BackgroundAlternaria alternata is the primary pathogen of potato leaf spot disease, resulting in significant potato yield losses globally....
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Design of a two functional permeable reactive barrier for synergistic enzymatic and microbial bioremediation of phenol-contaminated waters: laboratory column evaluation
The present study aimed to develop a system using a combination of enzymatic and microbial degradation techniques for removing phenol from...
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