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DAP12 interacts with RER1 and is retained in the secretory pathway before assembly with TREM2
DNAX-activating protein of 12 kDa (DAP12) is a transmembrane adapter protein expressed in lymphoid and myeloid lineage cells. It interacts with...
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12 Baker’s Yeast: a rising foundation for eukaryotic sphingolipid-mediated cell signaling
Saccharomyces cerevisiae has been an invaluable tool for the dissection of sphingolipid metabolic pathways and cloning of enzymes involved in...
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1 Phospholipid synthesis in mammalian cells
Phospholipids are the main components of biological membranes and as such act as the major permeability barrier between cells and the extracellular...
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2 Phospholipid synthesis and dynamics in plant cells
Phospholipids represent the second family of lipids after the galactolipids in photosynthetic tissues and the first in non-photosynthetic tissues....
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11 Plant sphingolipids
Plants contain a multiplicity of sphingolipid metabolites, such as long-chain bases, long-chain base phosphates, ceramides, glycosylceramides,...
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5 Sterol metabolism and functions in higher plants
Higher plants synthesize a bewildering array of sterols, with sitosterol, stigmasterol, and 24-methylcholesterol as major compounds. All plant...
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6 Sterol biochemistry and regulation in the yeast Saccharomyces cerevisiae
Saccharomyces cerevisiae has been a major model system for the study of sterol biosynthesis and function. All of the genes encoding the enzymes...
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7 Mammalian ACAT and DGAT2 gene families
Mammalian isozymes of ACAT, DGAT, and MGAT are encoded by the ACAT and DGAT2 gene families. These enzymes catalyze the synthesis of neutral lipid...
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Taxonomy and phylogenetic diversity among the yeasts
Yeasts are among the economically and scientifically most important eukaryotic microorganisms known. At present, there are 1,500 recognized species,...
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Comparative genomics and gene finding in fungi -- Supplement
Online Supplement to Chapter 1
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Degradation and Preservation of Organic Matter in Marine Sediments
Organic matter that is deposited in aquatic sediments is subject to an intense diagenetic reactor that determines how much organic carbon is...
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Telomeres in fungi
Telomeres are the functional elements concluding and defining each linear chromosome in eukaryotes. They play an essential role in protecting genetic...
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The genome of the filamentous fungus Ashbya gossypii: annotation and evolutionary implications
The 9.2 Mb genome of the filamentous fungus Ashbya gossypii consists of seven chromosomes carrying 4718 protein coding genes, 194 tRNA genes, at...
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Schizosaccharomyces pombe comparative genomics; from sequence to systems
The fission yeast Schizosaccharomyces pombe is becoming increasingly important as a model for the characterization and study of many globally...
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Genome evolution: Lessons from Genolevures
In the past years, yeast genome-sequencing programs have been widely developed. Two of them, namely Genolevures I and II, were devoted to the...
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FADD regulates adipose inflammation, adipogenesis, and adipocyte survival
Adipose tissue, aside from adipocytes, comprises various abundant immune cells. The accumulation of low-grade chronic inflammation in adipose tissue...
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Map** of Aegilops speltoides derived leaf rust and stripe rust resistance genes using 35K SNP array
Wheat is an essential food commodity cultivated throughout the world. However, this crop faces continuous threats from fungal pathogens, leaf rust...
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Vitamin C inactivates c-Jun N-terminal kinase to stabilize heart and neural crest derivatives expressed 1 (Hand1) in regulating placentation and maintenance of pregnancy
Vitamin C (VC) serves as a pivotal nutrient for anti-oxidation process, metabolic responses, and stem cell differentiation. However, its precise...
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Structural features of fungal genomes
Eighteen fungal genomes have been sequenced to date from a variety of taxonomic groups, with fifteen Ascomycota, two Basidomycota and one...
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Biological Markers for Anoxia in the Photic Zone of the Water Column
In this chapter we review the current state of knowledge on the occurrence of anoxic conditions in the water column of past depositional systems...