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Polycomb function in early mouse development
Epigenetic factors are crucial for ensuring proper chromatin dynamics during the initial stages of embryo development. Among these factors, the...
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A type II phosphatidylinositol-4-kinase coordinates sorting of cargo polarizing by endocytic recycling
Depending on their phosphorylation status, derivatives of phosphatidylinositol play important roles in vesicle identity, recognition and...
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Biological impact and therapeutic implication of tumor-associated macrophages in hepatocellular carcinoma
The tumor microenvironment is a complex space comprised of normal, cancer and immune cells. The macrophages are considered as the most abundant...
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Novel recycling strategy for distillers’ grains waste: prolonged biochar aging promotes cadmium immobilization and lettuce growth by regulating soil nutrient availability and bacterial composition
Background and aimsConverting distillers’ grains (DGs) into biochar (BC) is sustainable option for waste-recycling, but how different aging times and...
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Species Diversity of Anastrepha Fruit Flies (Diptera: Tephritidae) in Environments with Different Levels of Anthropogenic Changes
Studies on the diversity of Anastrepha species have been conducted mainly in agricultural orchards due to the economic importance of this insect...
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Biotic environment reinforcing the pertinacious clinically relevant COVID-19 associated mucormycosis: First report from Kashmir valley, India
Immuno-compromised COVID-19 patients being treated with glucocorticoids like Dexamethasone for prolonged periods had led to the surge of...
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Mass spectrometry-based proteomic landscape of rice reveals a post-transcriptional regulatory role of N6-methyladenosine
Rice is one of the most important staple food and model species in plant biology, yet its quantitative proteomes are largely uncharacterized. Here we...
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The neural network RTNet exhibits the signatures of human perceptual decision-making
Convolutional neural networks show promise as models of biological vision. However, their decision behaviour, including the facts that they are...
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Template-independent enzymatic synthesis of RNA oligonucleotides
RNA oligonucleotides have emerged as a powerful therapeutic modality to treat disease, yet current manufacturing methods may not be able to deliver...
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Tumor evolution metrics predict recurrence beyond 10 years in locally advanced prostate cancer
Cancer evolution lays the groundwork for predictive oncology. Testing evolutionary metrics requires quantitative measurements in controlled clinical...
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The nature of the last universal common ancestor and its impact on the early Earth system
The nature of the last universal common ancestor (LUCA), its age and its impact on the Earth system have been the subject of vigorous debate across...
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Precise in vivo RNA base editing with a wobble-enhanced circular CLUSTER guide RNA
Recruiting the endogenous editing enzyme adenosine deaminase acting on RNA (ADAR) with tailored guide RNAs for adenosine-to-inosine (A-to-I) RNA base...
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Deep 3D histology powered by tissue clearing, omics and AI
To comprehensively understand tissue and organism physiology and pathophysiology, it is essential to create complete three-dimensional (3D) cellular...
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Status of truffle science and cultivation in North America
BackgroundTruffles are subterranean fungal fruiting bodies that are highly prized for their culinary value. Cultivation of truffles was pioneered in...
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Phytoseiid mites benefited from organic fertilization by increasing the population of Tyrophagus mites in apple orchards
This study explores sustainable agricultural practices by examining the role of organic materials in enhancing native predatory mites for controlling...
