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Combined effect of polystyrene nanoplastic and di-n-butyl phthalate on testicular health of male Swiss albino mice: analysis of sperm-related parameters and potential toxic effects
Plastics, especially polystyrene nanoplastic particles (PSNPs), are known for their durability and absorption properties, allowing them to interact...
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Influence of toll-like receptor-4 antagonist on bacterial load of asthma in Swiss albino mice: targeting TLR4/MD2 complex pathway
Air pollution and environmental issues significantly impact life, resulting in the emergence and exacerbation of allergic asthma and other chronic...
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Design and development of whole-body rodent inhalation chamber for exposure to Aroclor 1232 in Swiss albino mice
The development of whole-body inhalational chambers for acute toxicity risk assessment of aerosols in rodents is of key importance in clinical and...
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Determination of dose- and time-dependent hepatotoxicity and apoptosis of Lanthanum oxide nanoparticles in female Swiss albino mice
Nanosized lanthanum oxide particles (La2O3) are commonly utilized in various industries. The potential health risks associated with La2O3...
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Effect of TLR3/dsRNA complex inhibitor on Poly(I:C)-induced airway inflammation in Swiss albino mice
Rhinovirus infection frequently causes COPD and asthma exacerbations. Impaired anti-viral signaling and reduced viral clearance have both been seen...
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Renal-protective effect of Asparagus officinalis aqueous extract against lead-induced nephrotoxicity mouse model
Lead is one of the cursed substances that threaten all human life. Lead poisoning can occur through food or water contaminations and it is hard to be...
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Mechanistic study of copper nanoparticle (CuNP) toxicity on the mouse uterus via apelin signaling
Copper nanoparticles (CuNPs) have been widely utilized in various applications. Due to its wider application, humans are at risk of its exposure. It...
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Polydatin reduces aflatoxin-B1 induced oxidative stress, DNA damage, and inflammatory cytokine levels in mice
This study showed the protective effect of polydatin (PD), which has an antioxidant activity against oxidative stress in mice caused by aflatoxin B 1 ...
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Exploring Therapeutic Potential of Indian Ayurvedic Plants for Parkinson’s Disease Treatment
Parkinson’s disease is a neurodegenerative disorder having its root in the degeneration of dopamine producing neurons in the substantia nigra region... -
Protocatechuic acid counteracts oxidative stress and inflammation in carrageenan-induced paw edema in mice
Protocatechuic acid (PCA), a phenolic compound found in teas, fruits, and vegetables, is widely recognized with its antioxidant and anti-inflammatory...
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Health Effects of Long Term Exposure to Arsenic—A Pathological and Genotoxic Approach
Pollution is increasing day by day in the environment due to variations in natural and anthropogenic activities that contaminates and infects all... -
Antioxidant role of selenium against maneb-induced cardiotoxicity in mice
The current study was conducted to assess the beneficial effect of selenium (Se) on maneb-induced cardiotoxicity and fatty acid alterations in adult...
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Topiramate potential neurotoxicity and mitigating role of ginger oil in mice brain
Topiramate has multiple pharmacological mechanisms that are efficient in treating epilepsy and migraine. Ginger has been established to have...
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Impact of Bisphenol A on Structure and Function of Mitochondria: A Critical Review
Bisphenol A (BPA) is an industrial chemical used extensively to manufacture polycarbonate plastics and epoxy resins. Because of its...
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Overview of deltamethrin residues and toxic effects in the global environment
Pyrethroids are synthetic organic insecticides. Deltamethrin, as one of the pyrethroids, has high insecticidal activity against pests and parasites...
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Arsenic-induced oxidative stress, cholinesterase activity in the brain of Swiss albino mice, and its amelioration by antioxidants Vitamin E and Coenzyme Q10
Arsenic toxicity becomes one of the major public health issues in several countries. Chronic and acute exposure to arsenic has been reported to be...
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Dose-dependent hepatic toxicity and oxidative stress on exposure to nano and bulk selenium in mice
Selenium is an essential mineral naturally found in soil, water, and some of the food and is required as essential elements in human and animal body....
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A comprehensive analysis of the animal carcinogenicity data for glyphosate from chronic exposure rodent carcinogenicity studies
Since the introduction of glyphosate-tolerant genetically-modified plants, the global use of glyphosate has increased dramatically making it the most...
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Placental transfer and hazards of silver nanoparticles exposure during pregnancy: a review
Many products contain silver nanoparticles, which are adsorbed by living organisms and then go through biological barriers. In particular,...
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Oral exposure of deltamethrin and/or lipopolysaccharide (LPS) induced activation of the pulmonary immune system in Swiss albino mice
The deltamethrin, a synthetic pyrethroid, is used worldwide and has been linked with several type of acute toxicity. However, effect of low level of...