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Modulation of Different Signaling Pathways in Liver Cancer by Arsenic Trioxide
The greatest health concern facing the globe today is still cancer. In order to defeat various malignancies, researchers are now racing to develop... -
Constant light exposure and/or pinealectomy increases susceptibility to trichloroethylene-induced hepatotoxicity and liver cancer in male mice
Exposure to light at night, pineal gland impairment, and the environmental pollutant trichloroethylene (TCE) have serious implications for health and...
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Inverse association between plasma chlordecone concentrations and progression of alcoholic liver fibrosis: the role of liver metabolism
Background and AimsChlordecone is a persistent organochlorinated insecticide, extensively used in the French West Indies and has been contaminating...
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Health risk assessment of metals in chicken meat and liver in Egypt
This study aimed to evaluate the concentration of metals such as aluminum (Al), cadmium (Cd), lead (Pb), barium (Ba), bismuth (Bi), cobalt (Co),...
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Impacts of Climate Change on Environmental Toxins and Pollutants Causing Liver Health Problems
The purpose of this chapter is to illustrate the impacts of climate change on environmental pollutants, chemical or biological pollutants, which are... -
Toxic Effects of Atrazine on Liver and Underlying Mechanism: A Review
Atrazine (ATR) is one kind of herbicide, which is widely used for weeding of dry crops such as corn, sorghum, and fruit trees. Due to its long...
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Protective efficacy of luteolin against aflatoxinB1-induced toxicity, oxidative damage, and apoptosis in the rat liver
One particularly harmful mycotoxin, aflatoxin B1 (AFB 1 ), usually triggers liver toxicity and oxidative stress in both humans and other mammals....
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Persistent Organic Pollutants released from decomposed adipose tissue affect mitochondrial enzyme function in the brain and eyes other than the liver
Persistent organic pollutants (POPs) are toxic chemicals that can accumulate in the human body, and particularly in adipose tissue. POPs can induce...
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Protective effects of Persea americana fruit and seed extracts against chemically induced liver cancer in rats by enhancing their antioxidant, anti-inflammatory, and apoptotic activities
This study aims to explore the chemopreventive mechanisms of hydroethanolic extracts from avocado ( Persea Americana ) in diethylnitrosamine...
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Naringin and naringenin counteract taxol-induced liver injury in Wistar rats via suppression of oxidative stress, apoptosis and inflammation
This research aimed to evaluate the preventing effects of naringin, naringenin, and their combination on liver injury induced by Taxol (paclitaxel)...
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Water Security and Its Impact on the Liver and Gut Health in Africa
Water is always linked to the productive capacity of human beings and to ecosystems’ well-being, livelihoods, and sustained development. It can also... -
Associations of arsenic exposure with liver injury in US adults: NHANES 2003–2018
Arsenic is a natural element with complex toxicity. Long-term exposure to arsenic can cause a variety of health damage. In recent years, there are...
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Association of Strontium Exposure with Liver Function: A Cross-Sectional Study from a Mining Area in Hunan, China
Previous studies found that some metals could affect liver function. However, the effect of strontium (Sr) exposure on liver function has not been...
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Toxicologic effect and transcriptome analysis for sub-chronic exposure to carbendazim, prochloraz, and their combination on the liver of mice
Carbendazim (CBZ) and prochloraz (PCZ) are broad-spectrum fungicides used in agricultural peat control. Both fungicides leave large amounts of...
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Carcinogenicity of nicotine and signal pathways in cancer progression: a review
Smoking is a major environmental factor causing nearly a third of cancer-related deaths. Nicotine accounts for 95% of tobacco’s alkaloid content and...
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Environment factors, DNA methylation, and cancer
Today, the rapid development of science and technology and the rapid change in economy and society are changing the way of life of human beings and...
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Grape seed extract prevents chlorpyrifos-induced toxicity in rat liver through the modulation of phase I detoxification pathway
Chlorpyrifos (CPF) poisoning is a public health problem for which there is not currently any effective prophylaxis. In this study, we investigated...
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Hg and Se in Muscle and Liver of Blue Shark (Prionace glauca) from the Entrance of the Gulf of California: An Insight to the Potential Risk to Human Health
The blue shark ( Prionace glauca ) is the most commonly caught species of Elasmobranchii at the entrance to the Gulf of California. Although fins are...
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Prospective association between phthalate exposure in childhood and liver function in adolescence: the Ewha Birth and Growth Cohort Study
BackgroundPhthalate exposure is ubiquitous due to the widespread use of plastic products in daily life, and affects several health outcomes,...
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Cadmium, Cellular Senescence, and Cancer
Cadmium (Cd) is an environmentally widespread toxic heavy metal with adverse effects on human health. Exposure to Cd is almost unavoidable in the...