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Early life cold and heat exposure impacts white matter development in children
Prenatal life and childhood represent periods that are vulnerable to environmental exposures. Both cold and heat may have negative impacts on...
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Early life stress, prenatal secondhand smoke exposure, and the development of internalizing symptoms across childhood
BackgroundPrior findings relating secondhand tobacco smoke (SHS) exposure and internalizing problems, characterized by heightened anxiety and...
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Effect of WiFi signal exposure in utero and early life on neurodevelopment and behaviors of rats
The aim of this study is to examine the long-term effects of prenatal and early-life WIFI signal exposure on neurodevelopment and behaviors as well...
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Early life exposure to secondhand tobacco smoke and eating behaviors at age 12 years
BackgroundPrenatal or early childhood secondhand tobacco smoke (SHS) exposure increases obesity risk. However, the potential mechanisms underlying...
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Characterization of Adverse Outcomes from Legacy-Contaminated Groundwater Exposure to Early Life Stages of Fathead Minnow
Complex mixtures of chemicals present in groundwater at legacy-contaminated industrial sites can pose significant risks to adjacent surface waters....
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Effect of Early-Life Exposure of Polystyrene Microplastics on Behavior and DNA Methylation in Later Life Stage of Zebrafish
Microplastic contamination has received increasing attention in recent years, and concern regarding the toxicity of microplastics to the environment...
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Early-life residential green spaces and traffic exposure in association with young adult body composition: a longitudinal birth cohort study of twins
BackgroundGlobally, the rapid increase of obesity is reaching alarming proportions. A new approach to reduce obesity and its comorbidities involves...
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Exposure to second-hand smoke during early life and subsequent sleep problems in children: a population-based cross-sectional study
BackgroundPrevious studies have revealed that current secondhand smoke exposure showed highly suggestive evidence for increased risk of simultaneous...
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Does early life exposure to exogenous sources of reactive oxygen species (ROS) increase the risk of respiratory and allergic diseases in children? A longitudinal cohort study
BackgroundExcess reactive oxygen species (ROS) can cause oxidative stress damaging cells and tissues, leading to adverse health effects in the...
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Environmental exposures in early-life and general health in childhood
BackgroundEarly-life environmental exposures are suspected to be involved in the development of chronic diseases later in life. Most studies...
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Combined effects of air pollution in adulthood and famine exposure in early life on type 2 diabetes
Famine exposure or air pollution is linked to type 2 diabetes mellitus (T2DM). However, their combined effects on T2DM remain largely unknown. A...
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Wildfire smoke exposure and early childhood respiratory health: a study of prescription claims data
Wildfire smoke is associated with short-term respiratory outcomes including asthma exacerbation in children. As investigations into developmental...
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Acute exposure of early-life stage zebrafish (Danio rerio) to Deepwater Horizon crude oil impairs glomerular filtration and renal fluid clearance capacity
The pronephros (early-stage kidney) is an important osmoregulatory organ, and the onset of its function occurs relatively early in some teleost...
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Embryonic benzophenone-3 exposure inhibited fertility in later-life female zebrafish and altered developmental morphology in offspring embryos
Benzophenone-3 (BP3), an organic UV filter widely used in personal care products, is ubiquitous in aquatic environments. Previous studies have shown...
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Associations of intrauterine exposure to manganese with fetal and early-childhood growth: a prospective prenatal cohort study
Prenatal manganese (Mn) exposure may be related to poor birth outcomes; however, there are few relevant epidemiological reports on the effects of...
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The impact of early-life exposure to three agrochemicals on survival, behavior, and gut microbiota of stingless bees (Partamona helleri)
Over the last few decades, agrochemicals have been partially associated with a global reduction in bees’ population. Toxicological assessment is...
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Developmental Toxicity and Cardiotoxicity Induced by PFOS and its Novel Alternative OBS in Early Life Stage of Zebrafish (Danio rerio)
As a novel alternative to perfluorooctane sulfonate (PFOS), sodium p -perfluorous nonenoxybenzene sulfonate (OBS) has been widely applied in many...
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Morphological and cardiac alterations after crude oil exposure in the early-life stages of the tropical gar (Atractosteus tropicus)
Fish development can be affected by environmental pollutants such as crude oil (anthropogenic or natural sources), causing alterations especially in...
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Intrauterine Exposure to Phthalates and Child Growth in the First Year of Life: Results from the BiTwin Cohort
Phthalates are among the endocrine-disrupting compounds with higher widespread in daily life. Our objective was to assess the associations between...
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Exposure to Endocrine-Disrupting Chemicals and Type 2 Diabetes Mellitus in Later Life
Type 2 diabetes mellitus (T2DM), one of the most common chronic metabolic diseases, involves a complex interaction among genetic, epigenetic, and...