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Cadmium-Induced Neurotoxicity
Cadmium-induced neurotoxicity has become a growing concern due to its potential adverse effects on the central nervous system. This chapter provides...
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Non-disclosure of developmental neurotoxicity studies obstructs the safety assessment of pesticides in the European Union
BackgroundIn the European Union (EU), the safety assessment of plant protection products relies to a large extent on toxicity studies commissioned by...
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Developmental toxicity and neurotoxicity assessment of R-, S-, and RS-propylene glycol enantiomers in zebrafish (Danio rerio) larvae
Propylene glycol (PG) is widely used in the foods, pharmaceuticals, oil industry, animal feed, cosmetics and other industries. Because of the...
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Neurotoxicity of microplastics: a CiteSpace-based review and emerging trends study
Microplastics, as a currently emerging pollutant, are gaining increasing attention from researchers in various fields. The purpose of this study is...
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PFAS: exploration of neurotoxicity and environmental impact
Per- and polyfluoroalkyl substances (PFAS) are widespread contaminants stemming from various industrial and consumer products, posing a grave threat...
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The sensitivity of the zebrafish embryo coiling assay for the detection of neurotoxicity by compounds with diverse modes of action
In the aim to determine neurotoxicity, new methods are being validated, including tests and test batteries comprising in vitro and in vivo...
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Bisphenol B induces developmental toxicity in zebrafish via oxidative stress
Bisphenol A (BPA) is a typical endocrine disruptor, and the use of bisphenol B (BPB) as a substitute is gradually increasing. Some studies have shown...
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Neurotoxicity of Glyphosate to Planarian Dugesia japonica
As one of the most widely used herbicides in agricultural industry, the residues of glyphosate (GLY) are frequent environmental pollutants....
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Exposure to the plasticizer dibutyl phthalate causes oxidative stress and neurotoxicity in brain tissue
The phthalate ester, dibutyl phthalate (DBP), is one of the endocrine-disrupting chemicals detected in various aquatic environments. Previous...
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Topiramate potential neurotoxicity and mitigating role of ginger oil in mice brain
Topiramate has multiple pharmacological mechanisms that are efficient in treating epilepsy and migraine. Ginger has been established to have...
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Low-dose exposure to malathion and radiation results in the dysregulation of multiple neuronal processes, inducing neurotoxicity and neurodegeneration in mouse
Neurodegenerative disorders are a debilitating and persistent threat to the global elderly population, carrying grim outcomes. Their genesis is often...
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Does ( −)-epigallocatechin-3-gallate protect the neurotoxicity induced by bisphenol A in vivo?
Bisphenol A (BPA) is one of the chemicals that is firmly accompanied by hippocampal neuronal injury. As oxidative stress appears to be a major...
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Developmental fluoride neurotoxicity: an updated review
BackgroundAfter the discovery of fluoride as a caries-preventing agent in the mid-twentieth century, fluoridation of community water has become a...
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Neurotoxicity in complex environmental mixtures—a case-study at River Danube in Novi Sad (Serbia) using zebrafish embryos
Acetylcholinesterase (AChE) inhibitors are an important class of neuroactive chemicals that are often detected in aquatic and terrestrial...
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The developmental neurotoxicity of legacy vs. contemporary polychlorinated biphenyls (PCBs): similarities and differences
Although banned from production for decades, PCBs remain a significant risk to human health. A primary target of concern is the develo** brain....
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Sex difference of pre- and post-natal exposure to six developmental neurotoxicants on intellectual abilities: a systematic review and meta-analysis of human studies
BackgroundEarly life exposure to lead, mercury, polychlorinated biphenyls (PCBs), polybromide diphenyl ethers (PBDEs), organophosphate pesticides...
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Dynamic alterations of locomotor activity and the microbiota in zebrafish larvae with low concentrations of lead exposure
Lead (Pb) is a ubiquitous heavy metal associated with developmental and behavioral disorders. The establishment of pioneer microbiota overlaps with...
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Acute lead acetate induces neurotoxicity through decreased synaptic plasticity-related protein expression and disordered dendritic formation in nerve cells
Lead (Pb) is a widespread environmental heavy metal that can damage the cerebral cortex and hippocampus, and reduce the learning and memory ability...
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Cytogenetic and developmental toxicity of bisphenol A and bisphenol S in Arbacia lixula sea urchin embryos
Bisphenol S (BP-S) is one of the most important substitutes of bisphenol A (BP-A), and its environmental occurrence is predicted to intensify in the...
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Human Health Risk Regulation of Reproductive Toxicity, Neurotoxicity, and Endocrine Disruption in Special Populations Exposed to Organophosphorus Flame Retardants
In this study, the joint toxicological characteristics of reproductive toxicity, neurotoxicity, and endocrine disruption (ED) by organophosphorus...
