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Bioinspired Hollow Mesoporous Silica Nanoparticles Coating on Titanium Alloy with Hierarchical Structure for Modulating Cellular Functions
3D-printed Porous Titanium Alloy Implants (pTi), owing to their biologically inertness and relatively smooth surface morphology, adversely affect the...
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Focal Adhesion
In the previous chapter, we learned about various biomaterial surfaces used for tissue engineering applications. Successful biomaterial surfaces...
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Cell Imaging
In the previous chapters, we have learned the basics and details of cell culture. Once cell culture is complete, there is a need to image the cells....
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Contact Guidance and Cell Patterning
Focal adhesion is an essential mechanism for cells to be anchored on the extracellular matrix (ECM). We can also utilize focal adhesion for...
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Cell Culture
In the previous chapter, we have learned the overview of tissue engineering principles and their applications. All tissue engineering applications...
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Guidelines for Finite Element Modeling of Cell Adhesion Process
Cell adhesion is a phenomenon characterizing cell-environment interactions and affects cellular behavior. Cell-substrate adhesion is ensured by focal...
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Integrated Analysis of MRNA and MiRNA Expression Profiles in dys-1 Mutants of C. Elegans After Spaceflight and Simulated Microgravity
Dystrophin-like dys-1 gene is expressed and required in muscle tissue, playing a vital role in gravisensing in Caenorhabditis elegans (C. elegans) ....
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Single Cell Adhesion in Cancer Progression
Quantitative assessment of cell adhesion during pathological development can potentially lead to a better elucidation of the mechanisms behind...
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Droplet-based bioprinting enables the fabrication of cell–hydrogel–microfibre composite tissue precursors
Composites offer the option of coupling the individual benefits of their constituents to achieve unique material properties, which can be of extra...
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Strain sensor on a chip for quantifying the magnitudes of tensile stress on cells
During cardiac development, mechanotransduction from the in vivo microenvironment modulates cardiomyocyte growth in terms of the number, area, and...
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Tissue-Engineered Skin Transplant
There are numerous examples of tissue-engineered (TE) transplants. TE skin transplant is perhaps the oldest and the most straightforward example of...
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Cell–substrate traction force regulates the fusion of osteoclast precursors through cell–cell interaction
The adhesion morphology of a cell monolayer results in a mechanical force inside cells, between cells, or between cells and substrates. The...
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Biomorphic porous Ti6Al4V gyroid scaffolds for bone implant applications fabricated by selective laser melting
Gyroid structures exhibiting interconnected porosity and mean curvature of zero have the closest resemblance to native bone. Interconnected Ti6Al4V...
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Modelling and targeting mechanical forces in organ fibrosis
Few efficacious therapies exist for the treatment of fibrotic diseases, such as skin scarring, liver cirrhosis and pulmonary fibrosis, which is...
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Human cells with osteogenic potential in bone tissue research
Bone regeneration after injury or after surgical bone removal due to disease is a serious medical challenge. A variety of materials are being tested...
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3D-printed tissue repair patch combining mechanical support and magnetism for controlled skeletal muscle regeneration
Physical forces, such as magnetic and mechanical stimulation, are known to play a significant role in the regulation of cell response. In the present...
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A micropore array-based solid lift-off method for highly efficient and controllable cell alignment and spreading
Interpretation of cell–cell and cell-microenvironment interactions is critical for both advancing knowledge of basic biology and promoting...
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Adhesion-enhancing coating embedded with osteogenesis-promoting PDA/HA nanoparticles for peri-implant soft tissue sealing and osseointegration
Following dental implantation, the characteristic bacterial milieu of the oral cavity may lead to peri-implant inflammation, which can negatively...
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On Valve Interstitial Cell Signaling: The Link Between Multiscale Mechanics and Mechanobiology
Heart valves function in one of the most mechanically demanding environments in the body to ensure unidirectional blood flow. The resident valve...
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Stimulation by Light
Tissue engineering techniques, to replace wounded or missing tissue, are advancing rapidly to ensure the speedy recovery of patients. However, this...