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Designing a Self-Assembled Peptide Nano-vaccine Against Staphylococcus aureus: An In Silico Approach
Staphylococcus aureus ( S. aureus ) is a bacterium capable of inducing a range of human infections, varying from mild skin infections to more serious...
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Digestive Enzyme Activity and Protein Degradation in Plasma of Heart Failure Patients
IntroductionHeart failure is associated with degradation of cell functions and extracellular matrix proteins, but the trigger mechanisms are...
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Edema in childhood nephrotic syndrome: possible genes–hormones interplay
BackgroundThe role of atrial natriuretic peptide (ANP) in edema formation in idiopathic nephrotic syndrome (INS) was studied before with conflicting...
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Synthetic extracellular matrices with function-encoding peptides
The communication of cells with their surroundings is mostly encoded in the epitopes of structural and signalling proteins present in the...
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Microbiological Nanotechnology
Most viruses are 10–200 nanometers in diameter and have regular nanostructures. The intersection of virology and nanoscience gave birth to the...
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Applications of Polypeptide Hydrogels in Cartilage-Regeneration Engineering
Articular cartilage defects are considered to be associated with the development of osteoarthritis. Research on relevant tissue regeneration is...
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Peptides-based vaccine against SARS-nCoV-2 antigenic fragmented synthetic epitopes recognized by T cell and β-cell initiation of specific antibodies to fight the infection
The World Health Organization has declared the rapidly spreading coronavirus to be a global pandemic. The FDA is yet to approve a vaccine for human...
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Target/Probe Interactions
This chapter is about interactions between molecules. The main aim here is to show how biological macromolecules interact with each other or with...
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Microbiological Nanotechnology
Most viruses are 10–200 nanometers in diameter and have regular nanostructures. The intersection of virology and nanoscience gave birth to the...
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Systematic Approaches on Extractable and Leachable Study Designs in Pharmaceuticals and Medical Devices: A Review
In recent years, the pharmaceutical industry has been adversely affected by an upsurge in the recall instances of pharmaceutical products. This is...
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Re-engineering Antimicrobial Peptides into Oncolytics Targeting Drug-Resistant Ovarian Cancers
IntroductionBacteria and cancer cells share a common trait—both possess an electronegative surface that distinguishes them from healthy mammalian...
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Engineering nanomaterial physical characteristics for cancer immunotherapy
The physical properties of nanomaterials — such as size, structure, shape, charge, mechanical strength and hydrophobicity — can directly or...
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Environmental Health and Safety of Engineered Nanomaterials
With rapid progress in nanotechnology and engineered nanomaterials (ENMs) being increasingly incorporated into consumer and industrial products, it...
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Pharmaceutical Nanotechnology
Pharmaceutical nanotechnology is a modern and unique branch of pharmaceutics based on nanotechnology that shows potential applications in treating...
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Fibrin in Nerve Tissue Engineering
This chapter will focus on the use of fibrin for peripheral nerve repair and regeneration. Important basic aspects of fibrinogen and fibrin will be...
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Artificial urinary biomarker probes for diagnosis
Urinalysis is a widely used medical test for healthcare monitoring and disease diagnosis. However, traditional urinalysis relies on endogenous...
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Surface Functionalization of Metallic Biomaterials: Present Trend and Future Perspectives
Surface functionalization is emerging as one of the most promising methodologies for properly improving surfaces, especially for biomedical...
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Targeted modulation of immune cells and tissues using engineered biomaterials
Therapies modulating the immune system offer the prospect of treating a wide range of conditions including infectious diseases, cancer and...
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Basic Principles of Nanotoxicology
The need for using multifunctional nanomaterials and nanobiotechnologies is determined by a broad development of modern industries like agriculture,...
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Single-Cell Proteomics
Single-cell proteomics refers to the analysis and characterization of proteins expressed in individual cells. The purpose of studying single-cell...