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Patient-specific modeling of left ventricle mechanics
We present a computational framework for the study of cardiac motion. The bio-mechanical model captures the passive and active properties of the...
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Applications of Artificial Intelligence in Cardiac Electrophysiology and Clinical Diagnosis with Magnetic Resonance Imaging and Computational Modeling Techniques
The underlying electrophysiological mechanisms and clinical treatments of cardiovascular diseases, which are the most common cause of morbidity and...
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Modeling cardiac microcirculation for the simulation of coronary flow and 3D myocardial perfusion
Accurate modeling of blood dynamics in the coronary microcirculation is a crucial step toward the clinical application of in silico methods for the...
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Computational modeling of hemodynamics and risk of thrombosis in the left atrial appendage using patient-specific blood viscosity and boundary conditions at the mitral valve
Hemodynamics play a vital role for the risk of thrombosis in the left atrial appendage (LAA) and left atrium (LA) for patients with atrial...
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Establishing In-silico Credibility of Patient-Specific Finite-Element Model in a Virtual Cohort
The feasibility of transcatheter aortic valve implantation (TAVI) has been investigated by in-silico modeling to assist clinicians in the...
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Integrated particle image velocimetry and fluid–structure interaction analysis for patient-specific abdominal aortic aneurysm studies
BackgroundUnderstanding the hemodynamics of an abdominal aortic aneurysm (AAA) is crucial for risk assessment and treatment planning. This study...
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Patient-specific bicuspid aortic valve hemodynamics study based on computer simulation and in vitro experiment
Bicuspid aortic valve (BAV) is a common congenital malformation of the aortic valve with various structural characteristics. Different types of BAV...
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Models for Closed-Loop Cardiac Control Using Vagal Nerve Stimulation
Vagal nerve stimulation has shown beneficial effects in treating cardiovascular diseases. However, the lack of clinical efficacy, as well as...
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Computational Studies on the Hemodynamics of Patient-Specific Human Carotid Artery
Atherosclerosis is a cardiovascular disease that affects large and medium-sized arteries and is characterised by intricate interactions between the...
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Estimation of anisotropic properties of CMR patient-specific left ventricle using the virtual field method
Left ventricle (LV) myocardial dysfunction has been recently investigated using the estimation of isotropic myocardial stiffness from magnetic...
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The Critical Role of Lumped Parameter Models in Patient-Specific Cardiovascular Simulations
Cardiovascular (CV) disease impacts tens of millions of people annually and carries a massive global economic burden. Continued advances in medical...
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Personalized evaluation of the passive myocardium in ischemic cardiomyopathy via computational modeling using Bayesian optimization
Biomechanics-based patient-specific modeling is a promising approach that has proved invaluable for its clinical potential to assess the adversities...
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Improved Three-Dimensional Reconstruction of Patient-Specific Carotid Bifurcation Using Deep Learning Based Segmentation of Ultrasound Images
Clinical examination is crucial during diagnostics of many diseases, including carotid artery disease. One of the most commonly used imaging...
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Enhancing Medical Imaging with Computational Modeling for Aortic Valve Disease Intervention Planning
Cardiovascular complications and death are potential outcomes of aortic valve disease, which is a severe medical condition that also carries a...
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Prediction of wall stress and oxygen flow in patient-specific abdominal aortic aneurysms: the role of intraluminal thrombus
In this study, the biomechanical role of intraluminal thrombus (ILT) in an abdominal aortic aneurysm (AAA) is investigated. The implications of ILT...
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2ARTs: A Platform for Exercise Prescriptions in Cardiac Recovery Patients
Due to limited access, increasing costs and an ageing population, the global healthcare system faces significant coverage problems that call for...
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Hemodynamic Modeling of Supraventricular Arrhythmias Using an Integrated Numerical Approach
The heart rhythm is controlled by electrical activity. Disorder in electrophysiology leads to cardiac arrhythmias (CA), which can be grouped into...
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Computational Analysis of Newtonian and Non-Newtonian Rheological Models for Patient-Specific Intracranial Aneurysm
This computational study is conducted to compare different blood models using a patient-specific intracranial aneurysm. A proper blood rheological...
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Models for Closed-Loop Cardiac Control Using Vagal Nerve Stimulation
Vagal nerve stimulation has shown beneficial effects in treating cardiovascular diseases. However, the lack of clinical efficacy, as well as...