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Predicting the Evolution of Cancer Stem Cell Subtypes Using a Machine Learning Framework
Cancer stem cells (CSCs) are subpopulation of cells in a tumor that are very important for analysis and treatment in clinical practice. The aim of...
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Stem Cells
In the previous chapters, we have learned the basics of mammalian cell culture, how to culture them (metabolism, feeding, and passaging), and how to...
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Application of Stem Cells in Dentistry: A Review Article
It is necessary to properly understand all biological processes behind the growth and development of the tissue if we want the tissue regeneration...
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Examining the Therapeutic Potential of Stem Cells in Treatment of Infertility
Millions of couples worldwide are affected by infertility, which is becoming a bigger health concern. Both men and women can experience infertility,...
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Mechanism of DNA Methylation in Stem Cells
DNA methylation is an important regulation mode in epigenetic mechanism. It affects a series of biological processes by regulating gene expression....
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Nickel (II) Phenylthiosemicarbazone Complex Induces Cytotoxicity, Oxidative Stress and Apoptosis in Human Leukemia Stem-like KG1a Cells
Thiosemicarbazones (TSCs) are compounds with different biological properties. Previous studies suggested that Thiosemicarbazones and their metal...
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Vascular Regeneration with Induced Pluripotent Stem Cell-Derived Endothelial Cells and Reprogrammed Endothelial Cells
Ischemic cardiovascular disease is the most prevalent health burden worldwide. Although significant progress has been made for the treatment, for...
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The Influence of Popular Antibiotics in Culture Medium on the Cell Motility and Superoxide Production of Mesenchymal Stem Cells
Antibiotics have become an integral part of routine cell culturing. Penicillin-streptomycin mixture and gentamicin are widely used to prevent...
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Generation of Human Myeloid-Derived Suppressor Cells from CD11b+ Cells in Vitro
Myeloid-derived suppressor cells (MDSC) are a group of myeloid cells that exert regulatory and angiogenic functions under physiological conditions...
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Modulation of cancer stemness property in head and neck cancer cells via circulatory fluid shear stress
Circulating tumor cells (CTCs) known as tumor cells dissociate from primary tumor sites and travel to secondary tumor sites via vasculature during...
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Transmembrane Receptor Dynamics as Biophysical Markers for Assessing Cancer Cells
As biophysical properties of tissues and cells play essential roles in cellular function, morphogenesis, and disease progression, numerous...
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Three-Dimensional Tumor Models to Study Cancer Stemness-Mediated Drug Resistance
Solid tumors often contain genetically different populations of cancer cells, stromal cells, various structural and soluble proteins, and other...
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Osteogenic differentiation of adipose-derived stem cells on dihydroartemisinin electrospun nanofibers
BackgroundAdipose tissue-derived stem cells (ASCs) are promising candidate in stem cell therapies, and maintaining their stemness potential is vital...
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Non-viral gene delivery to human mesenchymal stem cells: a practical guide towards cell engineering
In recent decades, human mesenchymal stem cells (hMSCs) have gained momentum in the field of cell therapy for treating cartilage and bone injuries....
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A modular microfluidic platform to study how fluid shear stress alters estrogen receptor phenotype in ER+ breast cancer cells
Metastatic breast cancer leads to poor prognoses and worse outcomes in patients due to its invasive behavior and poor response to therapy. It is...
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The Anticancer Effect of Magnetic Selenium-Based Nanocomposites on Tongue Carcinoma Stem Cells (In Vitro Study)
Oral tongue squamous cell carcinoma is an aggressive type of oral carcinomas. Resistance to conventional therapy is suggested to be caused by cancer...
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Role of mesenchymal stem cell-derived exosomes in the regeneration of different tissues
Exosomes are nanovesicles with multiple components used in several applications. Mesenchymal stem cells (MSCs) are well known for their great...
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A Comparative Study for Prediction of Hematopoietic Stem Cell Transplantation-Related Mortality
Multipotent hematopoietic stem cells are transplanted during hematopoietic stem cell therapy (HSCT) in order to replicate inside of a patient and...
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Substrate Stiffness Controls the Cell Cycle of Human Mesenchymal Stem Cells Via Cellular Traction
The microenvironment of human mesenchymal stem cells (hMSCs) regulates their self-renewal and differentiation properties. Previously, it was shown...
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Cell-Based Therapies in Cancer
The immune system can respond to immunogenic pathogens and clear damaged cells.