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Computational fluid–structure analysis of the impact of leaflet thickness and protrusion height on the flutter phenomenon in aortic valve bioprostheses
Although it is associated with the low lifetime of aortic valve bioprostheses, flutter has little been studied in the dynamics of these valves. To...
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Patient-specific bicuspid aortic valve hemodynamics study based on computer simulation and in vitro experiment
Bicuspid aortic valve (BAV) is a common congenital malformation of the aortic valve with various structural characteristics. Different types of BAV...
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Analysis of Aortic Valve Using a Finite Element Model
The major point of this consideration was the leaflet/aortic root interaction amid the cardiac cycle, counting the stresses created amid the... -
Enhancing Medical Imaging with Computational Modeling for Aortic Valve Disease Intervention Planning
Cardiovascular complications and death are potential outcomes of aortic valve disease, which is a severe medical condition that also carries a... -
Impact of calcific aortic valve disease on valve mechanics
The aortic valve is a highly dynamic structure characterized by a transvalvular flow that is unsteady, pulsatile, and characterized by episodes of...
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Trilayer anisotropic structure versus randomly oriented structure in heart valve leaflet tissue engineering
It has been hypothesized that leaflet substrates with a trilayer structure and anisotropic mechanical properties could be useful for the production...
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A parametric geometry model of the aortic valve for subject-specific blood flow simulations using a resistive approach
Cardiac valves simulation is one of the most complex tasks in cardiovascular modeling. Fluid–structure interaction is not only highly computationally...
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Assessment of valve implantation in the descending aorta as an alternative for aortic regurgitation patients not treatable with conventional procedures
Background:Aortic Regurgitation (AR) produces the entrance of an abnormal amount of blood in the left ventricle. This disease is responsible for high...
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A design-based model of the aortic valve for fluid-structure interaction
This paper presents a new method for modeling the mechanics of the aortic valve and simulates its interaction with blood. As much as possible, the...
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Challenges of aortic valve tissue culture – maintenance of viability and extracellular matrix in the pulsatile dynamic microphysiological system
BackgroundCalcific aortic valve disease (CAVD) causes an increasing health burden in the 21 st century due to aging population. The complex...
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Valve Design
A facility had to be installed and validated to produce On-X valves, a facility with finishing and quality programs that were complete and... -
Subject-specific multiscale modeling of aortic valve biomechanics
A Finite Element workflow for the multiscale analysis of the aortic valve biomechanics was developed and applied to three physiological anatomies...
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Transcatheter Aortic Valve Thrombogenesis: A Foreign Materials Perspective
PurposeThe initiation of thrombus formation in transcatheter aortic valves (TAVs) is not well understood. The foreign material components of a TAV...
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Fluid dynamics and blood damage in the dilated ascending aorta after mechanical prosthetic valve implantation: an in vitro study
The implantation of aortic valve prostheses is often associated with the dilation of the ascending aorta. It is well known that the modification of...
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Numerical Analysis of a simple Aortic Stenosis Model
In this study, a 3D simple aortic stenosis model was utilized to carry out simulations based on finite volume method. The stenosis in aorta is due to... -
On-X Valve Implantability
In 2008, Peter Zilla paid Medical Carbon Research Institute a visit in Austin, Texas. He had already been using the On-X valve, including doubles. He... -
Effects of process parameters and geometry on dimensional accuracy and surface quality of thin strut heart valve frames manufactured by laser powder bed fusion
Laser powder bed fusion (LPBF) is one of the most popular metal additive manufacturing technologies, which has found its applications in high-value...
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Effect of Mechanical Aortic Valves on Coronary Artery Flow in a Patient Suffering from Ischemic Heart Disease
Coronary arteryCoronary artery disease is the most common cardiovascular condition and one of the leading causes of death worldwide. Coronary... -
Influence of aortic valve tilt angle on flow patterns in the ascending aorta
Transcatheter aortic valve implantation (TAVI) has become the alternative procedure to high-risk patients who are diagnosed with aortic valve...
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Fluid–structure interaction modeling of compliant aortic valves using the lattice Boltzmann CFD and FEM methods
The lattice Boltzmann method (LBM) has been increasingly used as a stand-alone CFD solver in various biomechanical applications. This study proposes...