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A systematic review and meta-analysis of the impact of resveratrol on oral cancer: potential therapeutic implications
The present study aimed to investigate the impact of resveratrol on oral neoplastic parameters through a systematic review and meta-analysis....
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Healing effects of monomer and dimer resveratrol in a mouse periodontitis model
BackgroundThe antioxidant and anti-inflammatory effects of resveratrol have been reported previously. Particularly, monomeric trans-resveratrol has...
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Impact of resveratrol supplementation on clinical parameters and inflammatory markers in patients with chronic periodontitis: a randomized clinical trail
BackgroundPeriodontitis is one of the most common chronic inflammatory diseases in the world, which affects oral health. Resveratrol is a polyphenol...
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Effect and mechanism of resveratrol on ferroptosis mediated by p53/SLC7A11 in oral squamous cell carcinoma
ObjectiveResveratrol (Res) is a natural phytoestrogen with antitumor activity. This study sought to investigate the role of Res in ferroptosis in...
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The effect of 4-hexylresorinol administration on NAD+ level and SIRT activity in Saos-2 cells
Background4-hexylresorcinol (4HR) has been shown to have anti-oxidant activity similar to that of resveratrol. As resveratrol increases sirtuin...
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STAT1: a novel candidate biomarker and potential therapeutic target of the recurrent aphthous stomatitis
BackgroundThe recurrent aphthous stomatitis (RAS) frequently affects patient quality of life as a result of long lasting and recurrent episodes of...
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The potential preventive effect of dietary phytochemicals In Vivo
IntroductionChemoprevention refers to using specific substances during oncogenesis. Curcumin and catechins are both polyphenol types of...
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MicroRNA and their implications in dental pulp inflammation: current trends and future perspectives
MicroRNAs (miRNAs) are short, 19–23 nucleotide non-coding RNA molecules that regulate gene expression by silencing or degrading the target mRNA gene....
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Advances in novel therapeutic approaches for periodontal diseases
Periodontal diseases are pathological processes resulting from infections and inflammation affecting the periodontium or the tissue surrounding and...
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Sinensetin protects against periodontitis through binding to Bach1 enhancing its ubiquitination degradation and improving oxidative stress
Periodontitis is a chronic inflammatory and immune reactive disease induced by the subgingival biofilm. The therapeutic effect for susceptible...
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4-Hexylresorcinol: pharmacologic chaperone and its application for wound healing
4-Hexylresorcinol (4HR) is amphiphilic organic chemical and auto-regulator for micro-organism. As 4HR administration induces the stress on the...
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Association between retinol intake and periodontal health in US adults
BackgroundInflammation and oxidative stress are two hallmarks of periodontitis. Retinol is an antioxidant and suppresses expression of...
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Effect of Coenzyme Q10 on early wound healing after recession coverage surgery with the modified coronally advanced tunnel technique and a connective tissue graft: A 6-month, triple-blinded, randomized, placebo-controlled pilot trial
ObjectivesCoenzyme Q10 (CoQ10) or ubiquinone is one of a cell’s most important electron carriers during oxidative phosphorylation and many other...
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Circ_0099630 knockdown alleviates lipopolysaccharide-induced injuries of human periodontal ligament cells through the inhibition of TLR4 by releasing miR-409-3p
BackgroundPeriodontitis triggers tooth loss and affects the health of population worldwide. Emerging evidence hints that circular RNAs (circRNAs) are...
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The TMJ Troubles and Their Nutritional Consequences
The term temporomandibular disorder (TMD) can refer to any one of a number of conditions affecting the stomatognathic system. TMDs are characterized...
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β-defensin 2 synthesized by a cell-free protein synthesis system and encapsulated in liposomes inhibits adhesion of Porphyromonas gingivalis to oral epithelial cells
β-defensin 2 (BD-2), an antimicrobial peptide (AMP), is expressed by oral epithelial cells and plays an important role in innate immunity of the oral...
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The effect of 4-hexylresocinol administration on SCC-9 cells: mass spectrometric identification of proteins and cDNA microarray analysis
BackgroundIn stress situations, bacteria produce dormancy-inducing factors to stop cell growth. The dormancy-inducing factors may have an inhibitory...
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A novel in vitro periodontal pocket model to evaluate the effect of root surface instrumentation on biofilm-epithelial cell interactions
ObjectiveTo develop a novel in vitro periodontal pocket model for evaluating the effect of two different root surface instrumentation modalities on...
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Advances in regenerative medicine applications of tetrahedral framework nucleic acid-based nanomaterials: an expert consensus recommendation
With the emergence of DNA nanotechnology in the 1980s, self-assembled DNA nanostructures have attracted considerable attention worldwide due to their...
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Effect of curcumin on growth, biofilm formation and virulence factor gene expression of Porphyromonas gingivalis
Porphyromonas gingivalis is a keystone pathogen and major colonizer in host tissue which plays a pivotal role in periodontitis among the other...
