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Radiotherapy and the Oral Cavity
Radiotherapy plays a vital role in the management of head and neck cancer (HNC). Despite novel techniques reducing damage to healthy tissues, most... -
Rebamipide gargle and benzydamine gargle in prevention and management of chemo-radiotherapy and radiotherapy-induced oral mucositis in head and neck cancer patients (randomized clinical trial)
ObjectivesThis study aimed to evaluate the preventive and therapeutic effects of rebamipide gargle in comparison with benzydamine in head and neck...
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The Association of Salivary Flow Rate and Sleep Quality among Head and Neck Cancer Survivors after Radiotherapy
BackgroundHead and neck cancer survivors suffer from xerostomia and sleep disturbances after radiotherapy, both of which affect their quality of...
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A prediction model for xerostomia in locoregionally advanced nasopharyngeal carcinoma patients receiving radical radiotherapy
BackgroundThis study was to evaluate the predictors of xerostomia and Grade 3 xerostomia in locoregionally advanced nasopharyngeal carcinoma (NPC)...
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Oral health related quality of life of oral cancer patients treated with radiotherapy alone or with chemotherapy in a tertiary referral centre in Sri Lanka
BackgroundOral cancer is the number one cancer among males in Sri Lanka. Radiotherapy is a common treatment modality for oral cancer, but this can...
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An audit into the timing of dental extractions pre-head and neck radiotherapy and the prevalence of osteoradionecrosis
Objective It is recommended that radiotherapy for head and neck cancer commences ten days post-dental extractions to reduce the risk of...
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The clinical effect of radiotherapy on pulpal microvasculature: a systematic review
Introduction/objectives Radiotherapy (RT) has a detrimental effect on the histomorphology of oral tissues. Patients undergoing RT are at risk of...
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Effect of radiotherapy, immediate dentin sealing and irrigation simulating single- or two-visits endodontic treatment on the bond strength to pulp chamber dentin: an in vitro study
This study aimed to evaluate the influence of radiotherapy and different endodontic treatment protocols on the bond strength to pulp chamber dentin....
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Survival of dental implants and occurrence of mucosal overgrowth in patients with head and neck cancer treated with/without radiotherapy and mucosal graft—two-year follow-up
ObjectivesThe primary aim of the present study was to compare head and neck cancer treatment modality surgery and surgery with radiotherapy or...
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Clinical efficacy of endodontic protocols on reducing cultivable bacteria and endotoxin in infected root canal in patients submitted to head and neck radiotherapy: a randomised clinical trial
ObjectivesAssess the efficacy of biomechanical preparation using a reciprocating system followed by final irrigation protocols, then intracanal...
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Influence of radiotherapy on dental implants placed in individuals before diagnosed with head and neck cancer: focus on implant-bed-specific radiation dosage
ObjectivesThe influence of radiotherapy on implants placed before diagnosed as head and neck cancer (HNC) is a potentially informative but poorly...
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Association of photobiomodulation and antimicrobial photodynamic therapy in healing after multiple extraction in head and neck post-radiotherapy- a case report and literature review
PurposeTo report a clinical case involving the use of photobiomodulation (PBMT) and antimicrobial photodynamic therapy (aPDT) in the management of...
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Longitudinal study of the role of salivary proteins on radiation-related caries onset in head and neck cancer patients using 5000 ppm fluoride dentifrice up to one-year post-intensity modulated radiotherapy
ObjectivesLongitudinal assessment of the role of specific proteins on radiotherapy caries (RC) onset in head and neck cancer patients(HNC) up to...
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Dentists' perspectives on denture provision after radiotherapy for head and neck cancer: an exploratory study using the theoretical domains framework
Introduction Patients are often keen to replace their missing teeth after radiotherapy for head and neck cancer (HNC), yet such replacement does not...
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Dental loss after radiotherapy for head and neck cancer
Introduction In radiotherapy (RT) for head and neck cancer (HNC), dental morbidity is significant and it may result in loss of the dentition...
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Postoperative radiotherapy may not be necessary for locally advanced head and neck squamous cell carcinoma: a case-match multicentre study
BackgroundSome head and neck cancer surgeons found that many patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC) without...
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Translation and validation of Sinhala version of modified EORTC QLQ-OH15 in oral cancer patients who receive radiotherapy with or without chemotherapy in Sri Lanka
BackgroundThe recognition of patient-reported outcomes for oral cancer is important in improving patients’ quality of life. The aim of this study was...
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Radiotherapy changes the salivary proteome in head and neck cancer patients: evaluation before, during, and after treatment
ObjectivesSalivary glands are affected during radiotherapy in the head and neck region, leading to a reduction in salivary flow and changes its...
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Salivary IL-8 as a putative predictive biomarker of radiotherapy response in head and neck cancer patients
ObjectivesIonizing radiation increases the expression of a number of salivary proteins involved in immunoregulatory networks related to infection,...