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The potential preventive effect of dietary phytochemicals In Vivo
IntroductionChemoprevention refers to using specific substances during oncogenesis. Curcumin and catechins are both polyphenol types of...
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Impact of resveratrol supplementation on clinical parameters and inflammatory markers in patients with chronic periodontitis: a randomized clinical trail
BackgroundPeriodontitis is one of the most common chronic inflammatory diseases in the world, which affects oral health. Resveratrol is a polyphenol...
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Stem cell microencapsulation maintains stemness in inflammatory microenvironment
Maintaining the stemness of the transplanted stem cell spheroids in an inflammatory microenvironment is challenging but important in regenerative...
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Effect of epigallocatechin gallate on dental biofilm of Streptococcus mutans: An in vitro study
BackgroundStreptococcus mutans ( S. mutans ) plays a major role in the formation of dental caries. The aim of this study was to examine the effect of...
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Effect of flavonoids from grape seed and cranberry extracts on the microbiological activity of Streptococcus mutans: a systematic review of in vitro studies
ObjectiveTo provide an overview of the available scientific evidence from in vitro studies regarding the effect induced by the flavonoids contained...
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Investigating the efficacy of a varnish containing gallic acid on remineralization of enamel lesions: an in vitro study
This study evaluated the efficacy of a formulated remineralizing gallic acid (GA) varnish in treating artificial enamel caries lesions. Fifty-five...
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Advances in novel therapeutic approaches for periodontal diseases
Periodontal diseases are pathological processes resulting from infections and inflammation affecting the periodontium or the tissue surrounding and...
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Healing effects of monomer and dimer resveratrol in a mouse periodontitis model
BackgroundThe antioxidant and anti-inflammatory effects of resveratrol have been reported previously. Particularly, monomeric trans-resveratrol has...
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A systematic review and meta-analysis of the impact of resveratrol on oral cancer: potential therapeutic implications
The present study aimed to investigate the impact of resveratrol on oral neoplastic parameters through a systematic review and meta-analysis....
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Novel antimicrobial applications of copper oxide nanoparticles after combination with tissue conditioner used in complete prostheses
BackgroundTissue conditioners are used for treating and improving the tissues supporting complete dentures. On the other hand, recent advances in...
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The TMJ Troubles and Their Nutritional Consequences
The term temporomandibular disorder (TMD) can refer to any one of a number of conditions affecting the stomatognathic system. TMDs are characterized... -
Effects of hydroxyapatite nanorods prepared through Elaeagnus Angustifolia extract on modulating immunomodulatory/dentin–pulp regeneration genes in DPSCs
AbstractDental pulp stem cells (DPSCs) are a new type of mesenchymal stem cells (MSCs) found in the oral cavity with immunomodulation and tissue...
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An in vitro senescence model of gingival epithelial cell induced by hydrogen peroxide treatment
Gingival tissue shows progressive changes with aging and an in vitro model of gingival tissue could be useful in understanding age-associated oral...
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Curcumin as a Chemopreventive Agent for Oral Submucous Fibrosis
It is well known that there are no efficacious prevention and treatment strategies available for OSF. However, accumulating line of evidence suggests... -
The effect of 4-hexylresorinol administration on NAD+ level and SIRT activity in Saos-2 cells
Background4-hexylresorcinol (4HR) has been shown to have anti-oxidant activity similar to that of resveratrol. As resveratrol increases sirtuin...
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Color stability of nanohybrid and microhybrid composites after immersion in common coloring beverages at different times: a laboratory study
Objective/AimThis in vitro study aimed to evaluate the color stability of microhybrid and nanohybrid restorative composites after exposure to...
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The protective role of curcumin in human dental pulp stem cells stimulated by lipopolysaccharide via inhibiting NF-κB p65 phosphorylation to suppress NLRP3 inflammasome activation
ObjectivesThis study aims to investigate the anti-inflammatory effect of curcumin and underlying mechanisms regarding the modulation of the nod-like...
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Synergistic effect of thymoquinone and nystatin in the treatment of oral candidiasis; an in vitro study
The effectiveness of antifungal agents may be insufficient against resistant strains in some cases of oral candidiasis. The aim of this study was to...
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A novel in vitro periodontal pocket model to evaluate the effect of root surface instrumentation on biofilm-epithelial cell interactions
ObjectiveTo develop a novel in vitro periodontal pocket model for evaluating the effect of two different root surface instrumentation modalities on...
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The effect of cranberry juice and a cranberry functional beverage on the growth and metabolic activity of selected oral bacteria
BackgroundThe oral microbiota is a significant risk indicator for oral diseases, such as dental caries and periodontal inflammation. Much attention...