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Evaluation of matrix metalloproteinase-1, -2, -3, -7, and -13 gene polymorphisms in patients with chronic periodontitis and healthy controls
ObjectivesThe current study aimed to investigate the association of matrix metalloproteinase- (MMP-) 1, -2, -3, -7, and -13 gene polymorphisms with...
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Intervention with extracellular matrix metalloproteinase inducer in osteoclasts attenuates periodontitis-induced bone resorption
Extracellular matrix metalloproteinase inducer (EMMPRIN) plays critical roles in the regulation of inflammation and bone metabolism. The roles of...
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Influence of pre-treatment with diode laser and Nano silica coating crosslinking matrix metalloproteinase inhibitor on the stabilization of resin-dentine interfaces
PurposeThis study was performed to assess the impact of exposing the bonding agent to diode laser irradiation before cure and nano-silica coating...
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Applicability of an active matrix metalloproteinase-8 point-of-care test in an oral and maxillofacial surgery clinic: a pilot study
ObjectivesMatrix metalloproteinases are enzymes that participate in numerous inflammatory responses and have been targeted as biomarkers in numerous...
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Captopril inhibits matrix metalloproteinase activity and improves dentin bonding durability
ObjectivesWe investigated the inhibitory effects of captopril on matrix metalloproteinases (MMPs) and its effect as a primer on dentin bonding...
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Changes in salivary matrix metalloproteinase-3, -8, and -9 concentrations after 6 weeks of non-surgical periodontal therapy
BackgroundStudies using salivary inflammatory biomarkers for diagnosing and monitoring the progression of periodontal disease have garnered increased...
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Silencing matrix metalloproteinase-13 (Mmp-13) reduces inflammatory bone resorption associated with LPS-induced periodontal disease in vivo
ObjectivesThe aim of this study was to evaluate the effect of specific inhibition of MMP-13 on inflammation and inflammatory bone resorption in a...
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Alteration of extracellular matrix proteins in atrophic periodontal ligament of hypofunctional rat molars
ObjectivesThe aim of this study was to investigate the effect of mechanical force on possible dynamic changes of the matrix proteins deposition in...
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Osteoclast formation, inflammation, and matrix metalloproteinase-9 are downregulated in bone repair following root canal treatment in dogs teeth
ObjectivesThe aim of this study was to investigate the inflammatory infiltrate, osteoclast formation, and expression of MMP-9 during the healing...
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Influence of extracellular matrix scaffolds on histological outcomes of regenerative endodontics in experimental animal models: a systematic review
BackgroundDecellularized extracellular matrix (dECM) from several tissue sources has been proposed as a promising alternative to conventional...
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Effects of enamel matrix derivative in nonsurgical periodontal therapy on pro-inflammatory profiles, microbial environment and clinical outcome: a randomized clinical trial
ObjectivesThis study aimed to evaluate the impact of enamel matrix derivative (EMD) application following subgingival instrumentation of residual...
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Effects of diabetes on oxidative stress, periodontal ligament fiber orientation, and matrix metalloproteinase 8 and 9 expressions during orthodontic tooth movement
ObjectivesTo evaluate the influence of diabetes on oxidative stress, periodontal ligament (PDL) orientation, and matrix metalloproteinase (MMP) 8 and...
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Newly discovered clouting interplay between matrix metalloproteinases structures and novel quaternary Ammonium K21: computational and in-vivo testing
Aims and objectivesTo analyze anti-MMP mode of action of Quaternary Ammonium Silane (QAS, codenamed as k21) by binding onto specific MMP site using...
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Amelogenesis imperfecta in a Chinese family resulting from a FAM83H variation and the effect of FAM83H on the secretion of enamel matrix proteins
ObjectivesTo investigate the variant of an amelogenesis imperfecta (AI) family and to explore the function of the FAM83H (family with sequence...
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Peri-implant phenotype, calprotectin and MMP-8 levels in cases diagnosed with peri-implant disease
ObjectivesThe purpose of this prospective cohort study is to evaluate the effect of peri-implant phenotype (PPh) on the severity of peri-implant...
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BML-111 inhibit H2O2-induced pyroptosis and osteogenic dysfunction of human periodontal ligament fibroblasts by activating the Nrf2/HO-1 pathway
BackgroundPeriodontitis is a common and harmful chronic inflammatory oral disease, characterized by the destruction of periodontal soft and hard...
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Intrapocket application of tea tree oil gel in the treatment of stage 2 periodontitis
BackgroundThe gold standard in treatment of periodontitis is mechanical removing of dental biofilm but using local delivery drugs as adjunctive to...
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Relationship of MMP-9 with the clinical course of apical periodontitis and the main bacterial species in the oral microbiota
Bacterial products, host immune cells and cytokines have been reported to play an important role in the pathogenesis of apical periodontitis (AP)....
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Kindlin-2 loss in condylar chondrocytes causes spontaneous osteoarthritic lesions in the temporomandibular joint in mice
The progressive destruction of condylar cartilage is a hallmark of the temporomandibular joint (TMJ) osteoarthritis (OA); however, its mechanism is...
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Increase Toll-like receptors 2 and 4 in apical periodontitis of rats with chronic liver disease
The aim of this study was to evaluate the influence of liver fibrosis (LF) on the expression of Toll-like receptors (TLR) 2 and 4 in apical...