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The Human Sweet Tooth
Humans love the taste of sugar and the word "sweet" is used to describe not only this basic taste quality but also something that is desirable or...
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Sporadic and multiple neurofibromas in the head and neck region: a retrospective study of 33 years
The neurofibroma occurs as isolated or multiple lesions frequently associated with neurofibromatosis type 1 (NF-1). The aim of this study was to...
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Developmental genetics of the dentition
Much is now known of the molecular signalling and genetic determinants for tooth development. Here, we discuss the current understanding of the...
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Pathogenesis of degenerative temporomandibular joint arthritides
Over the past decade, remarkable progress has been made in the study of molecular mechanisms involved in degenerative temporomandibular joint...
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Large-scale investigation of genomic markers for severe periodontitis
The purpose of the present study was to investigate the genomic markers for periodontitis, using large-scale single-nucleotide polymorphism (SNP)...
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Ethnic and Geographical Distributions of CYP2C19 Alleles in the Populations of Southeast Asia
The genetic polymorphism of drug-metabolizing enzymes has a major influence on the fate of xenobiotic substances, whether as drugs or absorbed from...
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Molecular Basis of Antimalarial Drug Resistance in Indonesia
Malaria continues to be a major public health problem in Indonesia. In fact over 3 million clinical cases of malaria and about 100 deaths are...
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A Case of Familial Meningococcal Disease Due to Deficiency in Mannosebinding Lectin (MBL)
Fall 1997, there was a small epidemic of type-C meningococcal disease in the Netherlands, which overlapped more or less the `bible belt’ (Bax et...
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Malaria on Islands
Despite a 50-year effort to control it, malaria remains one of the main public health problems worldwide. Existing tools for malaria control are...
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Human Deficiencies in Type-1 Cytokine Receptors Reveal the Essential Role of Type-1 Cytokines in Immunity to Intracellular Bacteria
Protective immunity to intracellular bacteria such as mycobacteria and salmonellae depends on an effective cell-mediated immune response (CMI). A...
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Human Genome Diversity and Disease on the Island Southeast Asia
The island Southeast Asia (also referred to in the literature as the Malay, the Southeast Asian, and, more recently, the Indo-Malaysian Archipelago),...
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Plasmodium Falciparum
Despite more than 100 years of intense scientific and clinical study, malaria is currently the second highest communicable cause of global mortality...
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Alpha Thalassaemia in Indonesia: Phenotypes and Molecular Defects
Alpha thalassaemia is a hereditary blood disorder characterized by haemolytic anaemia. It is caused by mutations in the α-globin genes which lead to...
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Prämolarentransplantation vom kind auf ein elternteil im rahmen der kieferorthopädischen serienextraktion
While allografting of human teeth holds all the risks and problems of immunological reactions or host-versus-graft reactions encountered in any organ...
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Über genetische Faktoren bei der Ätiologie von Lippen-Kiefer-Gaumen-Spalten
In the first section the significance of genetic factors in the etiology of manifest cleft lip and palates is discussed and which type of genetic...
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Zur Kenntnis der Vererbung multipler Zahnunterzahl
In this study the problems produced by congenital absence of teeth are considered. A group of 241 persons with missing teeth of the permanent...