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Non-surgical periodontal treatment improves rheumatoid arthritis disease activity: a meta-analysis
ObjectivesThe aim of the meta-analysis was to clarify the efficacy of non-surgical periodontal treatment (NSPT) in improving rheumatoid arthritis...
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Interleukin-1β regulates odontogenic ameloblast-associated protein gene transcription in human gingival epithelial cells
Junction epithelium (JE) is located apical to the bottom of the gingival sulcus and binds enamel to hemidesmosomes to protect the periodontal tissue...
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Association of cytokine patterns and clinical/laboratory parameters, medication and periodontal burden in patients with rheumatoid arthritis (RA)
To evaluate serum levels of the following cytokines in rheumatoid arthritis subjects with periodontal disease: Interleukin-6, -10, -17, and -23....
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Interaction of periodontitis and orthodontic tooth movement—an in vitro and in vivo study
ObjectivesThe aim of this in vitro and in vivo study was to investigate the interaction of periodontitis and orthodontic tooth movement on...
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Evaluation of adipokines and inflammatory mediator expression levels in patients with periodontitis and peri-implantitis: a cross-sectional study
ObjectivesThe aim of this study was to analyze the mRNA and protein expression of adiponectin, leptin, visfatin, tumor necrosis factor (TNF)-α, and...
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Effects of histamine and various histamine receptor antagonists on gene expression profiles of macrophages during compressive strain
PurposeTissue hormone histamine can accumulate locally within the periodontal ligament via nutrition or may be released during allergic reactions by...
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Gene expression analysis of toll like receptor 2 and 4, Dectin-1, Osteopontin and inflammatory cytokines in human dental pulp ex-vivo
BackgroundToll like receptors (TLR) 2 and 4 present on innate immune cells of the dental pulp detect cariogenic bacteria. Along with bacteria, C....
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IL-39 and IL-35 gingival crevicular fluid levels in diabetic patients with generalized periodontitis
ObjectivesThis research was performed to investigate if there is a role for IL-39 in immunopathogenesis of both systemically healthy and diabetic...
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Effects of ibuprofen and low-level laser therapy on orthodontic pain by means of the analysis of interleukin 1-beta and substance P levels in the gingival crevicular fluid
ObjectiveThe goal of this study was to compare the effects of ibuprofen and low-level laser therapy in alleviating orthodontic pain observed after...
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Fibrogenic Factors and Molecular Mechanisms
Transforming growth factor-β is the major factor that influences fibroblast activation, extracellular matrix production, and other aspects important...
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Are comorbidities associated with the cytokine/chemokine profile of persistent apical periodontitis?
ObjectivesThis study aimed to identify disease-related markers in persistent apical periodontitis (PAP) biopsies and examine whether these were...
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Ernährungsfaktoren und Inflammation
Nutritional factors are of central importance for dental health. The uptake of necessary nutrients via food not only provides the systemic...
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IL-23/IL-17 axis levels in gingival crevicular fluid of subjects with periodontal disease: a systematic review
BackgroundThe IL-23/IL-17 axis plays an important role in the immunopathogenesis of periodontal disease. A systematic review was conducted to...
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Clinical diagnostic value of IL-14, 1L-16 and SAA in periodontitis
ObjectivesPeriodontitis is a chronic infectious disease, which leads to inflammatory destruction of periodontal supporting tissues. Interleukin 14...
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LncRNA CASC 2 is upregulated in aphthous stomatitis and predicts the recurrence
BackgroundRecurrent aphthous stomatitis (RAS) is a common oral disease with unknown molecular pathogenesis. Our preliminary microarray analysis...
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The effects of decontamination methods of dental implant surface on cytokine expression analysis in the reconstructive surgical treatment of peri-implantitis
The aim of this trial was to analyze the effect of implant surface decontamination procedures combined with reconstructive surgical treatment (RST)...
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Inflammatory cytokines mediating the effect of oral lichen planus on oral cavity cancer risk: a univariable and multivariable mendelian randomization study
BackgroundWhile observational studies and experimental data suggest a link between oral lichen planus (OLP) and oral cavity cancer (OCC), the causal...
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Oral squamous carcinoma cell lysates provoke exacerbated inflammatory response in gingival fibroblasts
ObjectivesTo study whether damaged epithelial cells and gingival fibroblast could affect the expression of inflammatory cytokines in healthy cells.
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Positive correlational shift between crevicular antimicrobial peptide LL-37, pain and periodontal status following non-surgical periodontal therapy. A pilot study
BackgroundPeriodontitis has a high prevalence and uncertain recurrence. Unlike the pro-inflammatory cytokine profile, little is known about the...
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Association of interleukin-8 polymorphism (+ 781 C/T) with the risk of oral Lichen Planus disease
BackgroundOral Lichen Planus (OLP) is a chronic inflammatory mucosal disease. The pathogenesis of OLP is unknown. The Single Nucleotide Polymorphism...
