Search
Search Results
-
Regulation of matrix metalloproteinase-1 by Filifactor alocis in human gingival and monocytic cells
ObjectivesPeriodontitis is a highly prevalent chronic inflammatory disease caused by periodontopathogens, such as Filifactor alocis . This study...
-
A critical influence of HIF-1 on MMP-9 and Galectin-3 in oral lichen planus
ObjectiveOral lichen planus carries a risk for malignancy. The pathogenesis of the disease is mediated by various inflammatory mediators. Several...
-
Fibrogenic Factors and Molecular Mechanisms
Transforming growth factor-β is the major factor that influences fibroblast activation, extracellular matrix production, and other aspects important...
-
Diagnostic performance of a point-of-care test device for periodontitis using human saliva: a single-center, single-blinded, confirmatory study
ObjectiveRecently, matrix metalloproteinase-8 (MMP-8) has been used to diagnose periodontal disease in a point-of-care (POC) test in order to save...
-
Estimation of salivary matrix metalloproteinases- 12 (MMP- 12) levels among patients presenting with oral submucous fibrosis and oral squamous cell carcinoma
BackgroundOral squamous cell carcinoma is a global threat and accounts for approximately 90% of malignant oral lesions. The emergence of oral...
-
Relationship between chronic periodontitis and inflammatory cytokines in patients undergoing maintenance hemodialysis
ObjectivesTo investigate the correlation between serum and gingival crevicular fluid (GCF) levels of inflammatory cytokines and the association with...
-
The effect of antimicrobial photodynamic therapy on periodontal disease and glycemic control in patients with type 2 diabetes mellitus
ObjectivesThis study is aimed at determining the effect of concomitant antimicrobial photodynamic therapy (aPTD) on periodontal disease and glycaemic...
-
Healing: Tissue Regeneration and Repair
Regeneration and tissue repair processes, collectively known as healing, consist of a sequence of molecular and cellular events which occur to...
-
Expression of visfatin in gingival crevicular fluid and gingival tissues in different periodontal conditions: a cross-sectional study
BackgroundStudies have shown that visfatin is an inflammatory factor closely related to periodontitis. We examined the levels of visfatin in gingival...
-
Label-free quantitative proteomics reveals molecular correlates of altered biomechanical properties in molar incisor hypomineralization (MIH): an in vitro study
PurposeMolar-incisor hypomineralization (MIH) is a qualitative developmental defect of enamel that affects first permanent molars with or without...
-
Effects of customized CAD/CAM abutments on cytokine levels in peri-implant crevicular fluid during early implant healing: a pilot study
ObjectivesThis study aimed to assess levels of biomarkers associated with inflammation and tissue destruction in peri-implant crevicular fluid (PICF)...
-
Origin of MMP-8 and Lactoferrin levels from gingival crevicular fluid, salivary glands and whole saliva
BackgroundPathologically elevated levels of matrix metalloproteinase-8 (MMP-8) and Lactoferrin in oral fluids have been associated with the presence...
-
Identification by whole-exome sequencing of new single-nucleotide polymorphisms associated with molar-incisor hypomineralisation among the Lebanese population
ObjectiveMolar-incisor hypomineralization (MIH) is a developmental qualitative enamel defect, causing a worldwide challenging dental problem. The...
-
Production of TNF-𝛼 by macrophages stimulated with endodontic pathogens and its effect on the biological properties of stem cells of the apical papilla
ObjectivesThe first objective of the present study was to investigate TNF-𝛼 secretion by macrophages stimulated with endodontic pathogens and...
-
Radiomics analysis of [18F]-fluoro-2-deoxyglucose positron emission tomography for the prediction of cervical lymph node metastasis in tongue squamous cell carcinoma
ObjectivesThis study aimed to create a predictive model for cervical lymph node metastasis (CLNM) in patients with tongue squamous cell carcinoma...
-
Systemic inhibition of 5-lipoxygenase by MK-886 exacerbates apical periodontitis bone loss in a mouse model
BackgroundTo investigate if 5-LO selective inhibitor (MK-886) could be used for systemic treatment of experimentally induced apical periodontitis in...
-
Evaluating the relationship between ankylosing spondylitis and periodontal disease: a case–control study
ObjectivesThis study aimed to determine the possible relationship between periodontal disease and ankylosing spondylitis (AS) by evaluating clinical...
-
Biomarkers for diagnosis of stage III, grade C with molar incisor pattern periodontitis in children and young adults: a systematic review and meta-analysis
AimTo explore the existing salivary, gingival crevicular fluid (GCF), blood, and serum biomarkers associated with grade C molar-incisor pattern...
-
Matrix metalloproteinases and inhibitors in dentistry
ObjectivesMatrix metalloproteinase (MMP) expression has been associated with tissue development, invasive cancer cell behavior, and inflammation. The...
-
Effect of intracanal medicaments on matrix metalloproteinase-9 and vasoactive intestinal peptide secretion in periapical lesions of re-treated canals: a randomized controlled clinical study
ObjectiveThe aim of this study was to evaluate the effect of calcium hydroxide (Ca[OH] 2 ) and chlorhexidine (CHX) gel on matrix metalloproteinase-9...
