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Crusting and Ulceration of Lips: Erythema Multiforme
Erythema Multiforme (EM) is an acute, immune-mediated condition, induced by Herpes Simplex Virus (HSV) infection or by the use of certain medications...
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Association of the angiotensin I converting enzyme (ACE) gene polymorphisms with recurrent aphthous stomatitis in the Czech population: case–control study
BackgroundRecurrent aphthous stomatitis (RAS) is multifactorial disease with unclear etiopathogenesis. The aim of this study was to determine...
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Long-term haplodeficency of DSPP causes temporomandibular joint osteoarthritis in mice
BackgroundExtracellular matrix (ECM) protein malfunction or defect may lead to temporomandibular joint osteoarthritis (TMJ OA). Dentin...
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Dental pulp stem cells as a promising model to study imprinting diseases
Parental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting...
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The relationship between FOSB and SOCS3 gene polymorphisms and the susceptibility to periodontitis and osteopenia in the Chinese population
The aim is to analyze the relationship and significance of the FOS , FOSB , Suppressors of cytokine signaling ( SOCS ), and hypoxia-inducible factor 1 ( HIF1...
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The association between Dental Fluorosis and COL1A2 gene polymorphism among a Tunisian Population
Dental fluorosis (DF) is a prevalent developmental defect of tooth enamel caused by exposure to excessive fluoride, with the severity dependent on...
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Pathogenesis
The pathogenesis of OLP is not completely known and is the subject of various hypotheses. Among the most widely accepted hypotheses, we find the...
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WNT10A variants: following the pattern of inheritance in tooth agenesis and self-reported family history of cancer
ObjectivesThe aim of this study was the analysis of WNT10A variants in seven families of probands with various forms of tooth agenesis and...
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Polymorphic variants in genes related to stress co** are associated with the awake bruxism
BackgroundChronic stress is one of the leading predisposing factors in bruxism aetiology, but the influence of genetic factors is also suggested. We...
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Evaluation of the association between TNF-α-1031 T/C polymorphism with oral lichen planus disease
BackgroundOral lichen planus (OLP) is a T-cell-mediated autoimmune disease that affects the epithelial cells of the oral cavity. This study was...
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Periodontitis and Sjogren’s syndrome: a bidirectional two-sample mendelian randomization study
ObjectivesObservational studies indicated a controversial relationship between periodontitis (PD) and Sjogren’s syndrome (SS). To overcome...
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Family and case–control genetic study of MSX1 polymorphisms in peg-shaped teeth Jordanian population
BackgroundThis study aimed to investigate the genetic association of specific Single Nucleotide Polymorphisms (SNPs) within the muscle segment...
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Can tissue biomarkers be used to determine the prognosis of oral leukoplakia lesions with regards to malignant transformation?
Design Systematic review looking at published studies which aimed to identify human tissue biomarkers which could predict malignant transformation of...
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Association between periodontitis and breast cancer: two-sample Mendelian randomization study
ObjectivesThe purpose of this study was to investigate whether there is a causal relationship between periodontitis and breast cancer by Mendelian...
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Candida species biotypes and polyclonality of potentially virulent Candida albicans isolated from oral cavity of patients with orofacial clefts
ObjectivesThis study evaluated the incidence of Candida species, and the genetic diversity and virulence of C. albicans of the oral cavity from...
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Cheek alveolar soft part sarcoma recurrence at the primary site during follow-up: a case report and review of the literature
BackgroundAlveolar soft part sarcoma (ASPS) occurs most often in the deep muscles or fascia of the extremities in adults, with only 3.4% of these...
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Genetic causal association between rheumatoid arthritis and periodontitis: a bidirectional two-sample Mendelian randomization analysis
BackgroundA link between rheumatoid arthritis (RA) and periodontitis (PD) has been established. However, their causal relationship remains unclear...
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Curcumin as a Chemopreventive Agent for Oral Submucous Fibrosis
It is well known that there are no efficacious prevention and treatment strategies available for OSF. However, accumulating line of evidence suggests...
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In Vivo and In Vitro Experimental Evidence
This chapter deals with experimental evidence of known risk factors in creating an environment conducive for the development of oral submucous...
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Identification of BRAF V600E mutation in odontogenic tumors by high-performance MALDI-TOF analysis
Odontogenic tumors are rare lesions with unknown etiopathogenesis. Most of them are benign, but local aggressiveness, infiltrative potential, and...
