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Spatiotemporal Structure
We deal intensively with the spatiotemporal structure and the related insights, such as general and special relativity, the three arrows of time, the...
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Biomimetic bone-periosteum scaffold for spatiotemporal regulated innervated bone regeneration and therapy of osteosarcoma
The complexity of repairing large segment defects and eradicating residual tumor cell puts the osteosarcoma clinical management challenging. Current...
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Spatiotemporal and global profiling of DNA–protein interactions enables discovery of low-affinity transcription factors
Precise dissection of DNA–protein interactions is essential for elucidating the recognition basis, dynamics and gene regulation mechanism. However,...
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A pH/enzyme dual responsive PMB spatiotemporal release hydrogel promoting chronic wound repair
Suppressing persistent multidrug-resistant (MDR) bacterial infections and excessive inflammation is the key for treating chronic wounds. Therefore,...
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Caging-Decaging Strategies to Realize Spatiotemporal Control of DNAzyme Activity for Biosensing and Bioimaging
DNAzymes with RNA-cleaving activity have been widely used as biosensing and bioimaging tools for detection of metal ions. Despite the achievements,...
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An injectable photo-cross-linking silk hydrogel system augments diabetic wound healing in orthopaedic surgery through spatiotemporal immunomodulation
BackgroundThe complicated hyperglycaemic and chronic inflammation of diabetic wounds in orthopaedic surgery leads to dysregulated immune cell...
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A self-assembled bilayer polypeptide-engineered hydrogel for spatiotemporal modulation of bactericidal and anti-inflammation process in osteomyelitis treatment
BackgroundDrug resistance of pathogens and immunosuppression are the main causes of clinical stagnation of osteomyelitis. The ideal treatment...
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Recent advances in the temporal and spatiotemporal dynamics induced by bromate–sulfite-based pH-oscillators
The bromate–sulfite reaction-based pH-oscillators represent one of the most useful subgroup among the chemical oscillators. They provide strong H + -pul...
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Multi-functional Hollow Structures for Intelligent Drug Delivery
Multi-fountional hollow structures have emerged as promising platforms for intelligent drug delivery due to their unique properties, such as high...
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Mathematical Modeling of a Self-Oscillating Catalytic Reaction in a Flow Reactor
AbstractThe article is devoted to the analysis of possible spatiotemporal kinetic structures that can arise during catalytic oxidation reactions on...
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Self-assembly of stabilized droplets from liquid–liquid phase separation for higher-order structures and functions
Dynamic microscale droplets produced by liquid–liquid phase separation (LLPS) have emerged as appealing biomaterials due to their remarkable...
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Spatiotemporal distribution of chemical signatures exhibited by Myxococcus xanthus in response to metabolic conditions
Myxococcus xanthus is a common soil bacterium with a complex life cycle, which is known for production of secondary metabolites. However, little is...
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Tailoring the surface and interface structures of photocatalysts to enhance hydrogen production
Photocatalytic water splitting using semiconductor photocatalysts is a promising approach for the production of carbon-neutral, sustainable and clean...
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Structures, mechanisms and applications of RNA-centric CRISPR–Cas13
Prokaryotes are equipped with a variety of resistance strategies to survive frequent viral attacks or invading mobile genetic elements. Among these,...
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Audible sound-controlled spatiotemporal patterns in out-of-equilibrium systems
Naturally occurring spatiotemporal patterns typically have a predictable pattern design and are reproducible over several cycles. However, the...
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Ratiometric luminescent sensor based on BSA-coated gold/silver nanoclusters for the selective determination and spatiotemporal imaging of gallic acid in plants
A new fluorescence sensing strategy has been developed. Four bimetallic nanoclusters, gold/silver, gold/copper, gold/molybdenum and gold/cobalt, were...
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Probabilistic Multiscale Modeling of Fracture in Heterogeneous Materials and Structures
AbstractThe probabilistic aspects of multiscale modeling of the fracture of heterogeneous structures are considered. An approach combining...
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Spatiotemporal regulation of angiogenesis/osteogenesis emulating natural bone healing cascade for vascularized bone formation
Engineering approaches for growth factor delivery have been considerably advanced for tissue regeneration, yet most of them fail to provide a complex...
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Deep Learning for Green Chemistry: An AI-Enabled Pathway for Biodegradability Prediction and Organic Material Discovery
The increasing global demand for eco-friendly products is driving innovation in sustainable chemical synthesis, particularly the development of...
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Cation-π and electrostatic interactions co-driven assembly of two-dimensional heteropore supramolecular polymers with rapid iodine capture capability
Constructing two-dimensional (2D) supramolecular polymers with complicated hierarchical porosity significantly contributes to develo** effective...
