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Swelling and BSA Release Behaviors of pH Sensitive Hydrogel Beads
AbstractHydrogel beads was prepared to detect the swelling behavior and kinetics in different pH solutions after bovine serum albumin (BSA) was...
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Zerumbone delivery to tumor cells via pH-sensitive polymeric micelles
This study aimed to develop a smart drug delivery system for zerumbone as an anticancer agent, to enhance its therapeutic efficacy against tumors. To...
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Green Synthesis of Polyvinylpyrrolidone Coated Super-Paramagnetic Fe3O4 Nanoparticles for Controlled Release of Letrozole: A pH-Sensitive Drug Delivery System
This study aimed to biosynthesis Fe 3 O 4 nanoparticles using the Mentha longifolia extracts then modified with polyvinylpyrrolidone, and loaded with...
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N-vinylcaprolactam-based temperature and pH-sensitive graft hydrogels for controlled drug release of 5-FU: a comprehensive study on synthesis, characterization, and release kinetics
Stimuli-responsive polymers can be used for various purposes due to their amazing properties within the context of controlled release systems. In...
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Biogenic Synthesis and Characterization of pH-sensitive Magnetic PVA/Starch/MnFe2O4 Hydrogel for Prolonged Release of 5-Fluorouracil
Dual-stimuli sensitive hybrid Polyvinyl alcohol (PVA)/Starch/Manganese iron oxide (MnFe 2 O 4 ), i.e. PS/pp-MI hydrogel membranes were successfully...
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Synthesis and characterization of novel xanthan gum-based pH-sensitive hydrogel for metformin hydrochloride release
In the current study, the synthesis of hydrogel based on carboxymethyl tamarind kernel gum (CMTKG), poly(sodium acrylate) (PSA), xanthan gum (XG) and...
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The Construction of pH-Sensitive Starch-Based Carrier to Control the Delivery of Curcumin for Fish Preservation
Controlled release of curcumin by a pH-sensitive carrier provides long-term preservation, which extends the shelf lives of fish. FTIR, XRD, 1 H NMR,...
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Exploring the Role of Ag Nanoparticle Distribution in Novel pH-Sensitive Nanofibers Containing Hyaluronic Acid for Enhanced Wound Healing with Sustained Curcumin Release
The use of nanofiber patches has received considerable attention as a promising solution for overcoming challenges in drug delivery. In this study,...
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Fabrication and characterization of pH-sensitive, injectable, and antibacterial hydrogel based on graphene–chitosan for curcumin delivery
In this study, pH-sensitive and injectable hydrogel according to graphene and chitosan was easily manufactured using terephthaldialdehyde as a...
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Synthesis and characterization of bio-nanocomposite hydrogel beads based on magnetic hydroxyapatite and chitosan: a pH-sensitive drug delivery system for potential implantable anticancer platform
Magnetic bio-nanocomposite hydrogels are a promising platform for tissue engineering and drug delivery applications. This research presents the...
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(Magnetic laponite/κ-carrageenan)@chitosan core–shell carrier for pH-sensitive release of doxorubicin
Recently, nanoclay-based nanocomposites have gained much attentions in the preparation of drug delivery systems due to their excellent...
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Fabrication and evaluation of pH-sensitive guar gum/chitosan/poly(vinyl alcohol) composite for improved gastro-retention of metformin
Retention of drug in the harsh environment of gastrointestinal tract is a major problem faced in oral delivery system as drugs are prone to a...
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Alginate/carboxymethylcellulose-based hydrogels as pH-sensitive drug delivery systems: facile production with enhanced degradation, thermal and mechanical properties
AbstractpH-Sensitive alginate (ALG)/sodium carboxymethylcellulose (CMC) hydrogels were synthesized using a novel technique to utilize as a drug...
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Construction of Near-Laser Irradiation Controlled Drug Delivery Platform with Tungsten Disulfide Nanosheets/pH and Thermo-Sensitive Polymer Functionalized Hyper-branched Dendrimer for Anticancer Activity
Stimuli-responsive polymers are attracting great attention in the last decades as nanocarriers for controlled drug delivery systems. Due to their...
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Synthesis, characterization and swelling behavior of pH-sensitive polyvinylalcohol grafted poly(acrylic acid-co-2-acrylamido-2-methylpropane sulfonic acid) hydrogels for protein delivery
The aim of the current study was to fabricate a pH-sensitive hydrogels for controlled release of Bovine serum albumin (BSA) protein. In this research...
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Matrix–Drug Interactions for the Development of pH-Sensitive Alginate-Based Nanofibers as an Advanced Wound Dressing
Traditional wound dressings do not provide all the clinical demands due to the lack of multifunctionality. There is an increasing request for...
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Erlotinib-entrapped gellan gum/carboxymethyl fenugreek seed mucilage-based thermo/pH-sensitive matrices
Carboxymethyl fenugreek seed mucilage-grafted poly- N -isopropylacrylamide/montmorillonite [CFSM- g -PNIPA/MMT] nanocomposites (NCs) were dually...
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B7H3 targeting gold nanocage pH-sensitive conjugates for precise and synergistic chemo-photothermal therapy against NSCLC
BackgroundThe combination of drug delivery with immune checkpoint targeting has been extensively studied in cancer therapy. However, the clinical...
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A novel pH-and temperature sensitive polymer based on MoS2 modified poly (N-Isopropyl Acrylamide)/ allyl acetoacetate for doxorubicin delivery: synthesis, characterization, in-vitro release and cytotoxicity studies
In this paper, we aimed to develop the nanocarrier based on poly (N-isopropyl acrylamide)—allyl acetoacetate grafted MoS 2 nanosheets. The obtained...
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Macrophage membrane-camouflaged pH-sensitive nanoparticles for targeted therapy of oral squamous cell carcinoma
BackgroundOral cancer is the most common malignant tumor of the head and neck, and 90% of cases are oral squamous cell carcinoma (OSCC). Chemotherapy...
